Hepatitis C Virus RNA-dependent RNA Polymerase (NS5B) as a Mediator of the Antiviral Activity of Ribavirin

Journal of Biological Chemistry ◽

10.1074/jbc.c100349200 ◽

2001 ◽

Vol 276 (49) ◽

pp. 46094-46098 ◽

Author(s):

David Maag ◽

Christian Castro ◽

Zhi Hong ◽

Craig E. Cameron

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Antiviral Activity ◽

Rna Polymerase ◽

Hepatitis C Virus Rna ◽

Rna Dependent Rna Polymerase ◽

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Structure−Activity Relationship of Purine Ribonucleosides for Inhibition of Hepatitis C Virus RNA-Dependent RNA Polymerase

Journal of Medicinal Chemistry ◽

10.1021/jm030424e ◽

2004 ◽

Vol 47 (9) ◽

pp. 2283-2295 ◽

Author(s):

Anne B. Eldrup ◽

Charles R. Allerson ◽

C. Frank Bennett ◽

Sanjib Bera ◽

Balkrishen Bhat ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Rna Polymerase ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Hepatitis C Virus Rna ◽

Rna Dependent Rna Polymerase ◽

Structure Activity ◽

Virus Rna ◽

Relationship Of

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Modulation of Hepatitis C Virus RNA-dependent RNA Polymerase Activity by Structure-based Site-directed Mutagenesis

Journal of Biological Chemistry ◽

10.1074/jbc.m204657200 ◽

2002 ◽

Vol 277 (41) ◽

pp. 38838-38846 ◽

Author(s):

Patrick Labonté ◽

Vladimir Axelrod ◽

Atul Agarwal ◽

Ann Aulabaugh ◽

Anthony Amin ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Rna Polymerase ◽

Polymerase Activity ◽

Site Directed Mutagenesis ◽

Directed Mutagenesis ◽

Hepatitis C Virus Rna ◽

Rna Dependent Rna Polymerase ◽

Virus Rna ◽

Rna Polymerase Activity

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B-ring modified aurones as promising allosteric inhibitors of hepatitis C virus RNA-dependent RNA polymerase

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2014.04.005 ◽

2014 ◽

Vol 80 ◽

pp. 579-592 ◽

Author(s):

Amel Meguellati ◽

Abdelhakim Ahmed-Belkacem ◽

Wei Yi ◽

Romain Haudecoeur ◽

Marie Crouillère ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Rna Polymerase ◽

Hepatitis C Virus Rna ◽

Allosteric Inhibitors ◽

Rna Dependent Rna Polymerase ◽

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Identification and functional characterization of the nascent RNA contacting residues of the hepatitis C virus RNA-dependent RNA polymerase

RNA ◽

10.1261/rna.031914.111 ◽

2012 ◽

Vol 18 (8) ◽

pp. 1541-1552 ◽

Author(s):

R. Vaughan ◽

B. Fan ◽

J.-S. You ◽

C. C. Kao

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Rna Polymerase ◽

Functional Characterization ◽

Hepatitis C Virus Rna ◽

Rna Dependent Rna Polymerase ◽

Virus Rna ◽

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Hepatitis C Virus RNA-Dependent RNA Polymerase (NS5B Polymerase)

Current Topics in Microbiology and Immunology - The Hepatitis C Viruses ◽

10.1007/978-3-642-59605-6_11 ◽

2000 ◽

pp. 225-260 ◽

Author(s):

C. H. Hagedorn ◽

E. H. van Beers ◽

C. De Staercke

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Rna Polymerase ◽

Hepatitis C Virus Rna ◽

Rna Dependent Rna Polymerase ◽

Virus Rna ◽

Ns5b Polymerase

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Activation of protein kinase R by hepatitis C virus RNA-dependent RNA polymerase

Virology ◽

10.1016/j.virol.2019.01.024 ◽

2019 ◽

Vol 529 ◽

pp. 226-233 ◽

Author(s):

Ryosuke Suzuki ◽

Mami Matsuda ◽

Takashi Shimoike ◽

Koichi Watashi ◽

Hideki Aizaki ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Protein Kinase ◽

Rna Polymerase ◽

Protein Kinase R ◽

Hepatitis C Virus Rna ◽

Rna Dependent Rna Polymerase ◽

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New Non-nucleoside Inhibitors of Hepatitis C Virus RNA-Dependent RNA Polymerase

Biochemistry (Moscow) ◽

10.1023/b:biry.0000040204.82885.f1 ◽

2004 ◽

Vol 69 (7) ◽

pp. 782-788 ◽

Author(s):

A. V. Ivanov ◽

M. V. Kozlov ◽

A. O. Kuzyakin ◽

D. A. Kostyuk ◽

V. L. Tunitskaya ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Rna Polymerase ◽

Hepatitis C Virus Rna ◽

Rna Dependent Rna Polymerase ◽

Virus Rna ◽

Nucleoside Inhibitors

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An efficient, asymmetric solid-phase synthesis of benzothiadiazine-substituted tetramic acids: Potent inhibitors of the hepatitis C virus RNA-dependent RNA polymerase

Bioorganic & Medicinal Chemistry Letters ◽

10.1016/j.bmcl.2006.01.034 ◽

2006 ◽

Vol 16 (8) ◽

pp. 2205-2208 ◽

Author(s):

Karen A. Evans ◽

Deping Chai ◽

Todd L. Graybill ◽

George Burton ◽

Robert T. Sarisky ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Rna Polymerase ◽

Solid Phase Synthesis ◽

Solid Phase ◽

Hepatitis C Virus Rna ◽

Rna Dependent Rna Polymerase ◽

Phase Synthesis ◽

Virus Rna ◽

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Production and characterization of active hepatitis C virus RNA-dependent RNA polymerase

Protein Expression and Purification ◽

10.1016/j.pep.2010.01.004 ◽

2010 ◽

Vol 71 (2) ◽

pp. 147-152 ◽

Author(s):

Kisun Ryu ◽

Kyun-Hwan Kim ◽

Seong-Yeon Yoo ◽

Eun-Young Lee ◽

Keo-Heun Lim ◽

...

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Rna Polymerase ◽

Hepatitis C Virus Rna ◽

Rna Dependent Rna Polymerase ◽

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Preannealing of poly(A) template and oligo(dT) primer is not required for hepatitis C virus RNA-dependent RNA polymerase activity

Analytical Biochemistry ◽

10.1016/j.ab.2011.04.019 ◽

2011 ◽

Vol 416 (1) ◽

pp. 132-134

Author(s):

Ying-Kai Wang

Keyword(s):

Hepatitis C Virus ◽

Hepatitis C ◽

Rna Polymerase ◽

Polymerase Activity ◽

Hepatitis C Virus Rna ◽

Rna Dependent Rna Polymerase ◽

Virus Rna ◽

Rna Polymerase Activity

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