Critical modifications of the ISO-1 scaffold improve its potent inhibition of macrophage migration inhibitory factor (MIF) tautomerase activity

2006 ◽  
Vol 16 (13) ◽  
pp. 3376-3379 ◽  
Author(s):  
Kai Fan Cheng ◽  
Yousef Al-Abed
2014 ◽  
Vol 462 (2) ◽  
pp. 303-314 ◽  
Author(s):  
Nina Dickerhof ◽  
Nicholas J. Magon ◽  
Joel D. A. Tyndall ◽  
Anthony J. Kettle ◽  
Mark B. Hampton

We report the ability of oxidized epicatechins to modify the N-terminal proline of the pro-inflammatory cytokine MIF at equimolar concentrations.


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