Identification and structure–activity relationship of 2-morpholino 6-(3-hydroxyphenyl) pyrimidines, a class of potent and selective PI3 kinase inhibitors

2010 ◽  
Vol 20 (23) ◽  
pp. 6895-6898 ◽  
Author(s):  
Sabina Pecchi ◽  
Paul A. Renhowe ◽  
Clarke Taylor ◽  
Susan Kaufman ◽  
Hanne Merritt ◽  
...  
Keyword(s):  
Kinase Inhibitors ◽  
Structure Activity Relationship ◽  
Pi3 Kinase ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Of

Design, Synthesis, and Structure−Activity Relationship of 6-Alkynylpyrimidines as Potent Adenosine Kinase Inhibitors

2002 ◽  
Vol 45 (17) ◽  
pp. 3639-3648 ◽  
Author(s):  
Arthur Gomtsyan ◽  
Stanley Didomenico ◽  
Chih-Hung Lee ◽  
Mark A. Matulenko ◽  
Ki Kim ◽  
...  
Keyword(s):  
Kinase Inhibitors ◽  
Structure Activity Relationship ◽  
Adenosine Kinase ◽  
Activity Relationship ◽  
Design Synthesis ◽  
Structure Activity ◽  
Relationship Of

Synthesis and structure–activity relationship of trisubstituted thiazoles as Cdc7 kinase inhibitors

2014 ◽  
Vol 80 ◽  
pp. 364-382 ◽  
Author(s):  
Andreas Reichelt ◽  
Julie M. Bailis ◽  
Michael D. Bartberger ◽  
Guomin Yao ◽  
Hong Shu ◽  
...  
Keyword(s):  
Kinase Inhibitors ◽  
Structure Activity Relationship ◽  
Activity Relationship ◽  
Structure Activity ◽  
Cdc7 Kinase ◽  
Relationship Of

scholarly journals Discovery, Biological Evaluation, and Structure−Activity Relationship of Amidine Based Sphingosine Kinase Inhibitors

2010 ◽  
Vol 53 (7) ◽  
pp. 2766-2778 ◽  
Author(s):  
Thomas P. Mathews ◽  
Andrew J. Kennedy ◽  
Yugesh Kharel ◽  
Perry C. Kennedy ◽  
Oana Nicoara ◽  
...  
Keyword(s):  
Kinase Inhibitors ◽  
Sphingosine Kinase ◽  
Structure Activity Relationship ◽  
Biological Evaluation ◽  
Activity Relationship ◽  
Structure Activity ◽  
Relationship Of

Synthesis and Structure−Activity Relationship of Aminobenzophenones. A Novel Class of p38 MAP Kinase Inhibitors with High Antiinflammatory Activity

2003 ◽  
Vol 46 (26) ◽  
pp. 5651-5662 ◽  
Author(s):  
Erik Rytter Ottosen ◽  
Morten Dahl Sørensen ◽  
Fredrik Björkling ◽  
Tine Skak-Nielsen ◽  
Marianne Scheel Fjording ◽  
...  
Keyword(s):  
Map Kinase ◽  
Kinase Inhibitors ◽  
Antiinflammatory Activity ◽  
Structure Activity Relationship ◽  
P38 Map Kinase ◽  
Activity Relationship ◽  
Structure Activity ◽  
P38 Map Kinase Inhibitors ◽  
Relationship Of
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