Chemical constituents isolated from the Mongolian medicinal plant Sophora alopecuroides L. and their inhibitory effects on LPS-induced nitric oxide production in RAW 264.7 macrophages

2015 ◽  
Vol 25 (16) ◽  
pp. 3314-3318 ◽  
Author(s):  
Jaeyoung Kwon ◽  
Sunita Basnet ◽  
Jin Woo Lee ◽  
Eun-Kyoung Seo ◽  
Nanzad Tsevegsuren ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Medicinal Plant ◽  
Chemical Constituents ◽  
Raw 264.7 ◽  
Nitric Oxide Production ◽  
Inhibitory Effects ◽  
Raw 264.7 Macrophages ◽  
Oxide Production ◽  
Sophora Alopecuroides

Inhibitory effects of cranberry polyphenol and volatile extracts on nitric oxide production in LPS activated RAW 264.7 macrophages

2019 ◽  
Vol 10 (11) ◽  
pp. 7091-7102 ◽  
Author(s):  
Katie Moore ◽  
Luke Howard ◽  
Cindi Brownmiller ◽  
Inah Gu ◽  
Sun-Ok Lee ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Raw 264.7 ◽  
Nitric Oxide Production ◽  
Inhibitory Effects ◽  
Raw 264.7 Macrophages ◽  
Oxide Production ◽  
Health Promoting

Cranberry volatiles have received little attention for health-promoting properties.

Inhibitory effects of indoleα-lipoic acid derivatives on nitric oxide production in LPS/IFNγ activated RAW 264.7 macrophages

2015 ◽  
Vol 33 (3) ◽  
pp. 121-127 ◽  
Author(s):  
Arzu Zeynep Karabay ◽  
Aslı Koc ◽  
A. Selen Gurkan-Alp ◽  
Zeliha Buyukbingol ◽  
Erdem Buyukbingol
Keyword(s):  
Nitric Oxide ◽  
Lipoic Acid ◽  
Raw 264.7 ◽  
Nitric Oxide Production ◽  
Inhibitory Effects ◽  
Raw 264.7 Macrophages ◽  
Oxide Production

Chemical Constituents Isolated fromBletilla striataand Their Inhibitory Effects on Nitric Oxide Production in RAW 264.7 Cells

2017 ◽  
Vol 14 (2) ◽  
pp. e1600243 ◽  
Author(s):  
Joon Young Bae ◽  
Jin Woo Lee ◽  
Qinghao Jin ◽  
Hari Jang ◽  
Dongho Lee ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Chemical Constituents ◽  
Raw 264.7 Cells ◽  
Raw 264.7 ◽  
Nitric Oxide Production ◽  
Inhibitory Effects ◽  
Oxide Production

3-Amino-alkylated indoles: unexplored green products acting as anti-inflammatory agents

2020 ◽  
Vol 12 (1) ◽  
pp. 5-17 ◽  
Author(s):  
Sarah Mazzotta ◽  
Luca Frattaruolo ◽  
Matteo Brindisi ◽  
Cristina Ulivieri ◽  
Francesca Vanni ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Inflammatory Activity ◽  
Raw 264.7 ◽  
Nitric Oxide Production ◽  
Inhibitory Effects ◽  
Green Products ◽  
Raw 264.7 Macrophages ◽  
Oxide Production ◽  
Green Approach ◽  
Anti Inflammatory

Aim: Over the years, indole has proved to be a versatile scaffold for the design of molecules acting as anti-inflammatory agents. Materials & Methods: A small library of 3-amino-alkylated indoles has been obtained by an optimized Mannich green approach. The anti-inflammatory activity of the new 3-amino-alkylated indoles, GLYC 0–10, was evaluated in RAW 264.7 macrophages. Results: The anti-inflammatory activity of the new 3-amino-alkylated indoles, GLYC 0–10, was evaluatedn and, among them, GLYC 4, 5 and 9 displayed the greatest inhibitory effects on nitric oxide production, with IC50 values of 5.41, 4.22 and 6.3 μM, respectively. Conclusion: Our outcomes, overall, highlight the importance of the indole substitution in the anti-inflammatory activity of these compounds, exerted by acting on the interlinked NF-κB/ERK1/2 pathways.

Inhibitory Effect of Trimidox on Lipopolysaccharide-Induced Nitric Oxide Production in RAW 264.7 Macrophages

2007 ◽  
Vol 104 (3) ◽  
pp. 278-281 ◽  
Author(s):  
Syu-ichi Kanno ◽  
Mai Kakuta ◽  
Yasue Kitajima ◽  
Yuu Osanai ◽  
Kaori Kurauchi ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Inhibitory Effect ◽  
Raw 264.7 ◽  
Nitric Oxide Production ◽  
Raw 264.7 Macrophages ◽  
Oxide Production
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