Therapy-related myeloid neoplasm with bone marrow involvement, myelosarcoma, and a t(8;16)(p11.2;p13.3)—a case report

2014 ◽  
Vol 207 (10-12) ◽  
pp. 511-515 ◽  
Author(s):  
Sujata Chakraborty ◽  
Julia Adams ◽  
Mehdi Nassiri ◽  
Gail H. Vance
2014 ◽  
Vol 2014 ◽  
pp. 1-4 ◽  
Author(s):  
Pankit Vachhani ◽  
Prithviraj Bose

Myeloid sarcoma represents the proliferation of myeloblasts of acute myeloid leukemia (AML) at extramedullary sites. While extramedullary involvement in AML is uncommon in itself, isolated myeloid sarcomas, that is, myeloid sarcomas without any bone marrow involvement, are extremely rare and pose a diagnostic and therapeutic challenge. Here, we present the case of a middle-aged woman with isolated myeloid sarcoma in the stomach—an organ seldom involved by this disease. Additionally, the literature on the epidemiology, diagnosis, pathology, prognosis, and therapeutic options in myeloid sarcomas has been reviewed.


2021 ◽  
Vol 0 ◽  
pp. 0-0
Author(s):  
Janpreet S. Bhandohal ◽  
Leila Moosavi ◽  
Igor Garcia-Pacheco ◽  
Gian Yakoub ◽  
Rahul D. Polineni ◽  
...  

2014 ◽  
Vol 86 (5) ◽  
pp. 593
Author(s):  
Hyung Jun Kim ◽  
Jongha Park ◽  
Young-Don Joo ◽  
Soon Il Lee ◽  
Eun Ji Lee ◽  
...  

2009 ◽  
Vol 4 (1) ◽  
pp. 2 ◽  
Author(s):  
Teresa A Vela-Chávez ◽  
Myrna D Arrecillas-Zamora ◽  
L Yolanda Quintero-Cuadra ◽  
Falko Fend

2005 ◽  
Vol 164 (10) ◽  
pp. 616-620 ◽  
Author(s):  
Yusuke Shiozawa ◽  
Nobutaka Kiyokawa ◽  
Masahiro Saito ◽  
Junichiro Fujimoto ◽  
Jun-ichi Hata ◽  
...  

Cureus ◽  
2019 ◽  
Author(s):  
Paul Plantinga ◽  
Sadaf Rahman ◽  
Kamilia Rizkalla ◽  
Jessica G Shepherd ◽  
Chai W. Phua

2013 ◽  
Vol 6 ◽  
pp. CCRep.S12608 ◽  
Author(s):  
Lindsey Prochaska ◽  
Christopher Dakhil ◽  
Sharad Mathur

Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is an aggressive myeloid neoplasm derived from plasmacytoid monocytes. The most common presentation involves cutaneous manifestations, which are often accompanied by bone marrow involvement. The tumor cells reveal an immature blastic appearance and diagnosis is based on the expression of cluster of differentiation (CD)4 and CD56. The literature reports a high relapse rate and poor prognosis when treated with leukemia-type induction chemotherapy alone; however, long-term remission is attainable with allogeneic stem cell transplantation in the first complete remission. Here, we report the dismal course of a patient with BPDCN with cutaneous and bone marrow involvement unable to undergo an aggressive intervention.


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