Antegrade Diastolic Pulmonary Artery Flow Implies Right Ventricular Restrictionin Adult Cases

2017 ◽  
Vol 23 (10) ◽  
pp. S23
Author(s):  
Yuri Umeta ◽  
Hiroyuki Watanabe ◽  
Takako Iino ◽  
Mai Shimbo ◽  
Wakana Sato ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Right Ventricular ◽  
Pulmonary Artery Flow ◽  
Artery Flow

Exercise-induced cardio-pulmonary remodelling in endurance athletes: Not only the heart adapts

2019 ◽  
Vol 27 (6) ◽  
pp. 651-659 ◽  
Author(s):  
Blanca Domenech-Ximenos ◽  
Maria Sanz-de la Garza ◽  
Susanna Prat-González ◽  
Álvaro Sepúlveda-Martínez ◽  
Fatima Crispi ◽  
...  
Keyword(s):  
Ejection Fraction ◽  
Pulmonary Artery ◽  
Right Ventricular ◽  
Pulmonary Circulation ◽  
Ventricular Ejection ◽  
Endurance Athletes ◽  
Ventricular Ejection Fraction ◽  
Pulmonary Artery Flow ◽  
Exercise Induced ◽  
Artery Flow

Background The cumulative effects of intensive endurance exercise may induce a broad spectrum of right ventricular remodelling. The mechanisms underlying these variable responses have been scarcely explored, but may involve differential pulmonary vasculature adaptation. Our aim was to evaluate right ventricular and pulmonary circulation in highly trained endurance athletes. Methods Ninety-three highly trained endurance athletes (>12 h training/week at least during the last five years; age: 36 ± 6 years; 52.7% male) and 72 age- and gender-matched controls underwent resting cardiovascular magnetic resonance imaging to assess cardiac dimensions and function, as well as pulmonary artery dimensions and flow. Pulmonary vascular resistance (PVR) was estimated based on left ventricular ejection fraction and pulmonary artery flow mean velocity. Resting and exercise Doppler echocardiography was also performed in athletes to estimate pulmonary artery pressure. Results Athletes showed larger biventricular and biatrial sizes, slightly reduced systolic biventricular function, increased pulmonary artery dimensions and reduced pulmonary artery flow velocity as compared with controls in both genders ( p < 0.05), which resulted in significantly higher estimated PVR in athletes as compared with controls (2.4 ± 1.2 vs. 1.7 ± 1.1; p < 0.05). Substantially high estimated PVR values (>4.2 WU) were found in seven of the 93 (9.3%) athletes: those exhibiting an enlarged pulmonary artery (indexed area cm2/m2: 4.8 ± 0.6 vs. 3.9 ± 0.6, p < 0.05), a decreased pulmonary artery distensibility index (%: 43.0 ± 15.2 vs. 62.0 ± 17.4, p < 0.05) and a reduced right ventricular ejection fraction (%: 49.3 ± 4.5 vs. 53.6 ± 4.6, p < 0.05). Conclusions Exercise-induced remodelling involves, besides the cardiac chambers, the pulmonary circulation and is associated with an increased estimated PVR. A small subset of athletes exhibited substantial increase of estimated PVR related to pronounced pulmonary circulation remodelling and reduced right ventricular systolic function.

Utility of the Medtronic microvascular plug™ as a transcatheter implantable and explantable pulmonary artery flow restrictor in a swine model

2019 ◽  
Vol 93 (7) ◽  
pp. 1320-1328 ◽  
Author(s):  
Abdul H. Khan ◽  
Deepthi Hoskoppal ◽  
T. K. Susheel Kumar ◽  
Lindsey Bird ◽  
Kimberly Allen ◽  
...  
Keyword(s):  
Pulmonary Artery ◽  
Swine Model ◽  
Pulmonary Artery Flow ◽  
Artery Flow

Direct pulmonary vascular responses in the conscious newborn lamb

1980 ◽  
Vol 48 (1) ◽  
pp. 188-196 ◽  
Author(s):  
J. E. Lock ◽  
F. Hamilton ◽  
H. Luide ◽  
F. Coceani ◽  
P. M. Olley
Keyword(s):  
Pulmonary Artery ◽  
Pulmonary Arteries ◽  
Arterial Oxygen Tension ◽  
Arterial Oxygen ◽  
Vascular Effects ◽  
Flow Probe ◽  
Pulmonary Artery Flow ◽  
Artery Flow

Electromagnetic flow probes were placed around the right and left pulmonary arteries (RPA and LPA) of nine newborn lambs. Preliminary in vitro and in vivo experiments delineated the accuracy and limitations of this method of flow measurement and the value in vivo of a balloon occlusive zero. Six to nine days after surgery, catheters were placed in the aorta and a branch pulmonary artery permitting simultaneous measurements of RPA and LPA flow, pulmonary arterial pressure, and aortic pressure. Vasoactive agents were injected into one lung, and a shift in blood flow distribution reflected direct active vasoconstruction or vasodilation in that lung. With a normal arterial oxygen tension, acetylcholine had no direct effect on the pulmonary vessels, but indirectly lowered pulmonary resistance via its systemic effects. Histamine was a potent direct pulmonary vasoconstrictor, bradykinin was a weak direct dilator, norepinephrine was a direct constrictor, prostaglandin E1 was a direct dilator, and prostaglandin F2a was a direct constrictor. These results demonstrate the feasibility of isolating the direct pulmonary vascular effects of certain pharmacologic agents using a double pulmonary artery flow probe preparation, agents using a double pulmonary artery flow probe preparation, without the use of anesthetics or extracorporeal perfusion circuits.

scholarly journals Effect of pulmonary vein ligation on pulmonary artery flow in dogs

1968 ◽  
Vol 55 (5) ◽  
pp. 668-671 ◽  
Author(s):  
George E. Miller ◽  
Torkel H. J. Aberg ◽  
Frank Gerbode
Keyword(s):  
Pulmonary Artery ◽  
Pulmonary Vein ◽  
Pulmonary Artery Flow ◽  
Artery Flow
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