Alcohol-mediated renal sympathetic neurolysis for the treatment of hypertension: The Peregrine™ infusion catheter

Author(s):  
Stefan Bertog ◽  
Alok Sharma ◽  
Felix Mahfoud ◽  
Atul Pathak ◽  
Roland E. Schmieder ◽  
...  
2020 ◽  
Vol 13 (4) ◽  
pp. 471-484 ◽  
Author(s):  
Felix Mahfoud ◽  
Jean Renkin ◽  
Horst Sievert ◽  
Stefan Bertog ◽  
Sebastian Ewen ◽  
...  

2013 ◽  
Vol 6 (1) ◽  
pp. 58-62
Author(s):  
Tushar Sharma ◽  
Anjay Rastogi ◽  
Rishi Talwar ◽  
Reza Khosravani Goshtaseb ◽  
Rohit Kumar ◽  
...  

Although the etiology of hypertension is complicated and multifactorial, the role of sympathetic overactivity as part of the pathogenesis in essential hypertension has been well described in the literature. A promising new treatment modality of Renal Sympathetic Denervation has become prominent with very enthusiastic support. This paper suggests that while the support may be overhyped, this new treatment modality may, with further research, become a powerful tool for a specific patient population. The history, benefits, and limitations of the procedure are discussed including, but not limited to, proper screening methodology, technical aspects, and procedural complications.


2016 ◽  
Vol 311 (6) ◽  
pp. F1267-F1270 ◽  
Author(s):  
Markus P. Schlaich

Renal nerves are key players in the regulation of kidney function and blood pressure control. Targeting the neurogenic mechanisms underlying hypertension and cardiac and renal disease has been attempted by means of surgical and pharmacologic approaches and most recently by catheter-based interventions aimed at disrupting renal sympathetic nerve traffic. The recent developments in the area and the relevant questions that need to be addressed to advance the field further are briefly reviewed in this article.


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