Protective role of Vitamin E pre-treatment on N-nitrosodiethylamine induced oxidative stress in rat liver

2005 ◽  
Vol 156 (2-3) ◽  
pp. 101-111 ◽  
Author(s):  
Anil K Bansal ◽  
Manju Bansal ◽  
Giridhar Soni ◽  
Deepak Bhatnagar
Keyword(s):  
Oxidative Stress ◽  
Vitamin E ◽  
Rat Liver ◽  
Protective Role ◽  
Pre Treatment

Association between alcohol-induced oxidative stress and membrane properties in synaptosomes: A protective role of vitamin E

2017 ◽  
Vol 63 ◽  
pp. 60-65 ◽  
Author(s):  
Vaddi Damodara Reddy ◽  
Pannuru Padmavathi ◽  
Saradamma Bulle ◽  
Ananda Vardhan Hebbani ◽  
Shakeela Begum Marthadu ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Vitamin E ◽  
Protective Role ◽  
Membrane Properties

Protective role of melatonin in cyclosporine A-induced oxidative stress in rat liver

2005 ◽  
Vol 5 (9) ◽  
pp. 1397-1405 ◽  
Author(s):  
Rita Rezzani ◽  
Barbara Buffoli ◽  
Luigi Rodella ◽  
Alessandra Stacchiotti ◽  
Rossella Bianchi
Keyword(s):  
Oxidative Stress ◽  
Rat Liver ◽  
Cyclosporine A ◽  
Protective Role

Protective role of erdosteine on vancomycin-induced oxidative stress in rat liver

2006 ◽  
Vol 291 (1-2) ◽  
pp. 155-160 ◽  
Author(s):  
Mehmet Sahin ◽  
Hakan Cam ◽  
Seref Olgar ◽  
Sevket Ercan Tunc ◽  
Cagatay Arslan ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Rat Liver ◽  
Protective Role

Protective role of vitamin E on the oxidative stress in Hansen's disease (Leprosy) patients

2005 ◽  
Vol 59 (10) ◽  
pp. 1121-1128 ◽  
Author(s):  
R Vijayaraghavan ◽  
C S Suribabu ◽  
B Sekar ◽  
P K Oommen ◽  
S N Kavithalakshmi ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Vitamin E ◽  
Protective Role ◽  
Hansen's Disease ◽  
Hansen’S Disease ◽  
Leprosy Patients

Protective Role of Natural Products in Cisplatin-Induced Nephrotoxicity

2019 ◽  
Vol 19 (14) ◽  
pp. 1134-1143 ◽  
Author(s):  
Nurul Raudzah Adib Ridzuan ◽  
Norhashima Abd Rashid ◽  
Faizah Othman ◽  
Siti Balkis Budin ◽  
Farida Hussan ◽  
...  
Keyword(s):  
Oxidative Stress ◽  
Natural Products ◽  
Antioxidant Enzymes ◽  
Antineoplastic Agent ◽  
Protective Role ◽  
Vitamin Supplementation ◽  
Anti Inflammatory ◽  
Pre Treatment ◽  
Higher Doses

Cisplatin is a widely used antineoplastic agent for the treatment of metastatic tumors, advanced bladder cancer and many other solid tumors. However, at higher doses, toxicities such as nephrotoxicity may appear. Cisplatin leads to DNA damage and subsequently renal cell death. Besides that, oxidative stress is also implicated as one of the main causes of nephrotoxicity. Several studies showed that numerous natural products: ginseng, curcumin, licorice, honey and pomegranate were able to reduce the oxidative stress by restoring the levels of antioxidant enzymes and also at the same time act as an anti-inflammatory agent. Furthermore, pre-treatment with vitamin supplementation, such as vitamin C, E and riboflavin markedly decreased serum urea and increased the levels of antioxidant enzymes in the kidney even after cisplatin induction in cancer patients. These natural products possess potent antioxidant and anti-inflammatory medicinal properties, and they can be safely used as a supplementary regime or combination therapy against cisplatin-induced nephrotoxicity. The present review focused on the protective role of a few natural products which is widely used in folk medicines in cisplatin-induced nephrotoxicity.

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