Pulmonary Arterial Hypertension in Patients Infected with the Human Immunodeficiency Virus

2022 ◽  
Vol 40 (1) ◽  
pp. 45-54
Author(s):  
Stephanie M. Hon ◽  
Rodolfo M. Alpizar-Rivas ◽  
Harrison W. Farber
2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Aibek E. Mirrakhimov ◽  
Alaa M. Ali ◽  
Aram Barbaryan ◽  
Suartcha Prueksaritanond

Human immunodeficiency virus- (HIV-) related pulmonary arterial hypertension (PAH) is a rare complication of HIV infection. The pathophysiology of HIV-related PAH is complex, with viral proteins seeming to play the major role. However, other factors, such as coinfection with other microorganisms and HIV-related systemic inflammation, might also contribute. The clinical presentation of HIV-related PAH and diagnosis is similar to other forms of pulmonary hypertension. Both PAH-specific therapies and HAART are important in HIV-related PAH management. Future studies investigating the pathogenesis are needed to discover new therapeutic targets and treatments.


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