Human Immunodeficiency Virus and Pulmonary Arterial Hypertension
Keyword(s):
Human immunodeficiency virus- (HIV-) related pulmonary arterial hypertension (PAH) is a rare complication of HIV infection. The pathophysiology of HIV-related PAH is complex, with viral proteins seeming to play the major role. However, other factors, such as coinfection with other microorganisms and HIV-related systemic inflammation, might also contribute. The clinical presentation of HIV-related PAH and diagnosis is similar to other forms of pulmonary hypertension. Both PAH-specific therapies and HAART are important in HIV-related PAH management. Future studies investigating the pathogenesis are needed to discover new therapeutic targets and treatments.
2013 ◽
Vol 34
(2)
◽
pp. 283-292
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2003 ◽
Vol 167
(10)
◽
pp. 1433-1439
◽