Human Immunodeficiency Virus and β-thalassemia Major: A “Competition of Guilt” for Pulmonary Arterial Hypertension. Report of A Case and A Review of the Literature

Hemoglobin ◽  
2010 ◽  
Vol 34 (1) ◽  
pp. 61-66 ◽  
Author(s):  
Giorgio Derchi ◽  
Maria E. Lai ◽  
Paolo Marcaccini ◽  
Maria P. Carta ◽  
Stefania Vacquer
Keyword(s):  
Human Immunodeficiency Virus ◽  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Thalassemia Major ◽  
Review Of The Literature ◽  
Immunodeficiency Virus ◽  
Pulmonary Arterial

scholarly journals Human Immunodeficiency Virus and Pulmonary Arterial Hypertension

2013 ◽  
Vol 2013 ◽  
pp. 1-11 ◽  
Author(s):  
Aibek E. Mirrakhimov ◽  
Alaa M. Ali ◽  
Aram Barbaryan ◽  
Suartcha Prueksaritanond
Keyword(s):  
Human Immunodeficiency Virus ◽  
Pulmonary Hypertension ◽  
Pulmonary Arterial Hypertension ◽  
Arterial Hypertension ◽  
Clinical Presentation ◽  
Rare Complication ◽  
Viral Proteins ◽  
Future Studies ◽  
Immunodeficiency Virus ◽  
Pulmonary Arterial

Human immunodeficiency virus- (HIV-) related pulmonary arterial hypertension (PAH) is a rare complication of HIV infection. The pathophysiology of HIV-related PAH is complex, with viral proteins seeming to play the major role. However, other factors, such as coinfection with other microorganisms and HIV-related systemic inflammation, might also contribute. The clinical presentation of HIV-related PAH and diagnosis is similar to other forms of pulmonary hypertension. Both PAH-specific therapies and HAART are important in HIV-related PAH management. Future studies investigating the pathogenesis are needed to discover new therapeutic targets and treatments.

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