A microfluidic surface-enhanced Raman scattering (SERS) sensor for microRNA in extracellular vesicles with nucleic acid-tyramine cascade amplification

2021 ◽  
Author(s):  
Yue Zhao ◽  
Xiaoxing Fang ◽  
Min Bai ◽  
Jin Zhang ◽  
Huahang Yu ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Raman Scattering ◽  
Extracellular Vesicles ◽  
Surface Enhanced Raman Scattering ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Cascade Amplification

scholarly journals Surface enhanced Raman scattering of extracellular vesicles for cancer diagnostics despite isolation dependent lipoprotein contamination

Nanoscale ◽  
2021 ◽  
Author(s):  
Hanna Koster ◽  
Tatu Rojalin ◽  
Alyssa Powell ◽  
Dina Pham ◽  
Rachel Mizenko ◽  
...  
Keyword(s):  
Raman Scattering ◽  
Extracellular Vesicles ◽  
Surface Enhanced Raman Scattering ◽  
Cancer Diagnostics ◽  
Diagnostic Utility ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering ◽  
Particle Counts

Given the emerging diagnostic utility of extracellular vesicles (EVs), it is important to account for non-EV contaminants. Lipoprotein present in EV-enriched isolates may inflate particle counts and decrease sensitivity to...

A sensitive SERS detection of miRNA using a label-free multifunctional probe

2015 ◽  
Vol 51 (94) ◽  
pp. 16836-16839 ◽  
Author(s):  
Hao Zhang ◽  
Yu Liu ◽  
Jian Gao ◽  
Junhui Zhen
Keyword(s):  
Nucleic Acid ◽  
Raman Scattering ◽  
Detection Method ◽  
Surface Enhanced Raman Scattering ◽  
Label Free ◽  
Strand Displacement ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sers Detection ◽  
Enhanced Raman Scattering

A novel surface enhanced Raman scattering (SERS) detection method is fabricated for miRNA based on a smart multifunctional probe for dual cyclical nucleic acid strand-displacement polymerization (CNDP).

Nanostructure-based surface-enhanced Raman scattering biosensors for nucleic acids and proteins

2016 ◽  
Vol 4 (10) ◽  
pp. 1757-1769 ◽  
Author(s):  
Jie Chao ◽  
Wenfang Cao ◽  
Shao Su ◽  
Lixing Weng ◽  
Shiping Song ◽  
...  
Keyword(s):  
Nucleic Acid ◽  
Raman Scattering ◽  
Nucleic Acids ◽  
Protein Detection ◽  
Surface Enhanced Raman Scattering ◽  
Label Free ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Enhanced Raman Scattering

Nanostructure-based SERS platforms have been developed for nucleic acid and protein detection ranging from label-free, labeled and multiplex analyses.

A sandwich-type surface-enhanced Raman scattering sensor using dual aptamers and gold nanoparticles for the detection of tumor extracellular vesicles

The Analyst ◽  
2020 ◽  
Vol 145 (19) ◽  
pp. 6232-6236
Author(s):  
Min Hou ◽  
Dinggeng He ◽  
Hongchang Bu ◽  
Huizhen Wang ◽  
Jin Huang ◽  
...  
Keyword(s):  
Gold Nanoparticles ◽  
Raman Scattering ◽  
Extracellular Vesicles ◽  
Surface Enhanced Raman Scattering ◽  
Raman Signal ◽  
Surface Enhanced ◽  
Surface Enhanced Raman ◽  
Sandwich Type ◽  
Enhanced Raman Scattering

A sandwich-type surface-enhanced Raman scattering (SERS) sensor using dual aptamers and gold-enhanced Raman signal probes has been successfully constructed for the detection of tumor-derived extracellular vesicles.

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