Study of a water-soluble supramolecular complex of curcumin and β-cyclodextrin polymer with electrochemical property and potential anti-cancer activity

2021 ◽  
Author(s):  
Wang Zhang ◽  
Ping Xiao ◽  
Liwei Lin ◽  
Fang Guo ◽  
Qingyue Wang ◽  
...  
Keyword(s):  
Electrochemical Property ◽  
Supramolecular Complex ◽  
Water Soluble ◽  
Cyclodextrin Polymer ◽  
Anti Cancer ◽  
Cancer Activity

A supramolecular complex of hydrazide-pillar[5]arene and bisdemethoxycurcumin with potential anti-cancer activity

2021 ◽  
Vol 110 ◽  
pp. 104764
Author(s):  
Fang Guo ◽  
Tao Xia ◽  
Ping Xiao ◽  
Qingyue Wang ◽  
Zhitong Deng ◽  
...  
Keyword(s):  
Supramolecular Complex ◽  
Anti Cancer ◽  
Cancer Activity

"Fullarazirman" Nano Water Soluble Fullerene C60-Manganese (II) Tri-Adduct Complex with Anti-Cancer Activity Comparable to Doxorubicin

2020 ◽  
Vol 16 (4) ◽  
pp. 481-491
Author(s):  
Sujeet Kumar Thakur ◽  
Saibal Saha ◽  
Prasenjit Guchhait ◽  
Sambasivan Venkat Eswaran
Keyword(s):  
Materials Science ◽  
Ultra Violet ◽  
Water Soluble ◽  
Complex Iii ◽  
Cancer Drug ◽  
Ionization Mass ◽  
Gravimetric Analysis ◽  
X Ray ◽  
Anti Cancer ◽  
Cancer Activity

There is continued interest in Nano Carbon Materials (NCMs) and two of these, Fullerene C60 and Graphene have received Nobel prizes. Low solubility in most solvents has been a stumbling block in their industrial use. We report here the successful synthesis of a new water soluble tri-adduct of Fullerene C60 using a two-step procedure to obtain the water soluble s-Tri-(1-aziridino-2, 3-dimethoxy-benzene-5-carboxylato-6-carboxylic acid)-H-Fullerene C60-Manganese (II) Complex ( III ). Matrix Assisted Laser Desorption Ionization Mass Spectrometry (MALDI-MS) and Electron Paramagnetic Resonance (EPR) studies critically helped recognize the presence of an atom of Manganese in the complex. The new complex was also characterized by Ultra violet-Visible (UV-Vis.). Fourier Transform-Infra Red (FT-IR) spectroscopy, Energy Dispersive X-ray analysis (EDAX), Scanning Electron Microscopy (SEM), Thermal Gravimetric Analysis (TGA), and powder X-ray diffraction. The new compound has been shown to possess anti-cancer activity comparable to Doxorubicin, currently the most used anti-cancer drug. This new water soluble Fullerene C60-Manganese (II) tri-adduct complex ( III ) thus holds much promise for the fields of biology, biochemistry, medicine, and materials science.

ANTICANCER EFFECT OF UVARIA GENUS

2014 ◽  
pp. 98-101
Author(s):  
Thi Bich Hien Le ◽  
Viet Duc Ho ◽  
Thi Hoai Nguyen
Keyword(s):  
Biological Activities ◽  
Current Trend ◽  
Healthcare Systems ◽  
Chemical Compositions ◽  
Cancer Therapies ◽  
Pharmacological Effects ◽  
Anticancer Effect ◽  
Anti Cancer ◽  
Tropical Areas ◽  
Cancer Activity

Nowadays, cancer treatment has been a big challenge to healthcare systems. Most of clinical anti-cancer therapies are toxic and cause adverse effects to human body. Therefore, current trend in science is seeking and screening of natural compounds which possess antineoplastic activities to utilize in treatment. Uvaria L. - Annonaceae includes approximately 175 species spreading over tropical areas of Asia, Australia, Africa and America. Studies on chemical compositions and pharmacological effects of Uvaria showed that several compound classes in this genus such as alkaloid, flavonoid, cyclohexen derivaties, acetogenin, steroid, terpenoid, etc. indicate considerable biological activities, for example anti-tumor, anti-cancer, antibacterial, antifungal, antioxidant, etc. Specifically, anti-cancer activity of fractions of extract and pure isolated compounds stands out for cytotoxicity against many cancer cell lines. This study provides an overview of anti-cancer activity of Uvaria and suggests a potential for further studies on seeking and developing novel anti-cancer compounds. Key words: Anti-cancer, Uvaria.

Sign in / Sign up

Export Citation Format

Share Document