Fe-Ce-Mn catalysts loaded on TiO2-ZrO2materials were prepared by sol-gel method and then were investigated for low temperature selective catalytic reduction (SCR) of NO with NH3. It was found that the NO conversions over Fe-Ce-Mn/TiO2-ZrO2was slightly improved compared with that over Ce-Mn/TiO2-ZrO2. The results showed that 96% NO conversion was obtained over Fe-Ce-Mn/TiO2-ZrO2with the molar ratio of Fe/Mn=0.3. A comparative study of Fe-Ce-Mn/TiO2- ZrO2and Ce-Mn/TiO2-ZrO2for NO conversions at 140°C in the presence of H2O and SO2proved that Fe-Ce-Mn/TiO2-ZrO2exhibited higher resistance to H2O and SO2than that of without Fe catalysts. In addition, Fe-Ce-Mn/TiO2-ZrO2presented 90.49% NO conversion after cutting off the injection of SO2and H2O.