Gas chromatography–mass spectrometry of carbonyl compounds in cigarette mainstream smoke after derivatization with 2,4-dinitrophenylhydrazine

2004 ◽  
Vol 1027 (1-2) ◽  
pp. 25-35 ◽  
Author(s):  
Ji-Zhou Dong ◽  
Serban C Moldoveanu
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Carbonyl Compounds ◽  
Gas Chromatography Mass Spectrometry ◽  
Mainstream Smoke ◽  
Chromatography Mass Spectrometry ◽  
Cigarette Mainstream Smoke

scholarly journals Simultaneous Determination of Four Aldehydes in Gas Phase of Mainstream Smoke by Headspace Gas Chromatography-Mass Spectrometry

2019 ◽  
Vol 2019 ◽  
pp. 1-6 ◽  
Author(s):  
Xiaotao Zhang ◽  
Ruoning Wang ◽  
Li Zhang ◽  
Jianke Wei ◽  
Yibin Ruan ◽  
...  
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Gas Phase ◽  
Gas Chromatography Mass Spectrometry ◽  
Headspace Gas Chromatography ◽  
Mainstream Smoke ◽  
Chromatography Mass Spectrometry ◽  
Headspace Gas ◽  
Cigarette Mainstream Smoke

A method for simultaneous determination of acetaldehyde, propionaldehyde, acrolein, and crotonaldehyde in gas phase of cigarette mainstream smoke by headspace gas chromatography-mass spectrometry was developed and validated. Gas phase components of mainstream cigarette smoke were extracted with methanol, and then the samples were separated on a DB 624 (60 m, 0.32 mm x 1.8 mm) column, analyzed with headspace gas chromatography-mass spectrometry, and quantified by isotope internal standard. The linearities of acetaldehyde, propionaldehyde, acrolein, and crotonaldehyde were good (R2>0.992). The recoveries of acetaldehyde, propionaldehyde, acrolein, and crotonaldehyde were between 78.5% and 115%. The relative standard deviations were less than 10%. The limits of detection and limits of quantitation were 0.014 μg/cigarette ~0.12 μg/cigarette and 0.045 μg/cigarette ~0.38 μg/cigarette, respectively. The method had advantage of high sensitivity, it did not require derivatization of 2,4-dinitrophenylhydrazine and avoided a large number of adverse reactions during the process of derivation to improve the accuracy of result, and it was suitable for quantitative analysis of four aldehydes in gas phase of cigarette mainstream smoke.

scholarly journals RAZNOLIKOST KLONSKIH KANDIDATOV Vitis vinifera 'ŠKRLET BIJELI' V AROMATIČNIH SNOVEH, DOLOČENIH S PLINSKO KROMATOGRAFIJO-MASNO SPEKTROSKOPIJO

2016 ◽  
Vol 107 (2) ◽  
pp. 483 ◽  
Author(s):  
Ivana Vladimira Petric ◽  
Tatjana Košmerl ◽  
Ivan Pejić ◽  
Veronika Kubanović ◽  
Emil Zlatić
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Vitis Vinifera ◽  
Carbonyl Compounds ◽  
Significant Variation ◽  
Aroma Compounds ◽  
Gas Chromatography Mass Spectrometry ◽  
Aroma Profile ◽  
Grapevine Variety ◽  
Chromatography Mass Spectrometry

The aim of this work was to investigate existence presence and stability of must specific aroma compounds (monoterpenes C<sub>13</sub>-norisoprenoids, C<sub>6</sub>-alcohols, alcohols, esters and carbonyl compounds) and which can be used to establish differences among clone candidates of 'Škrlet bijeli' (<em>Vitis vinifera</em> L.) grapevine variety. The compounds responsible for the varietal aroma profile were determined by gas chromatography- mass spectrometry (GC-MS), in must samples of ten clone candidates grown on two vineyard sites for three consecutive years. Significant variation among clone candidates is shown in 22 out of the total 35 identified aroma compounds. Significant impact of the vineyard site on the clone candidate’s aroma profile was identified. Differences in primary aroma compounds responsible for flavour of 'Škrlet bijeli' variety, linalool, terpinolen, nerol and α-terpineol, were not significant among clone candidates, while remarkable differences were established for β-damascenone. Contrary to expectation, monoterpene geraniol was not detected. Other identified aroma compounds (<em>trans</em>-ocimene, 2-methyl-1-butanol, myrcene, α-phelandrene, <em>cis</em>-ocimene and 3-methyl-1-butanol) noticeably less participate in total flavour description, but they still enable notable clone candidates discrimination.

scholarly journals Analysis of Selected Carbonyl Compounds in Tobacco Samples by Using Pentafluorobenzylhydroxylamine Derivatization and Gas Chromatography-Mass Spectrometry

2014 ◽  
Vol 26 (3) ◽  
pp. 86-97 ◽  
Author(s):  
Mingliang Bao ◽  
Peter J. Joza ◽  
Andrew Masters ◽  
William S. Rickert
Keyword(s):  
Mass Spectrometry ◽  
Gas Chromatography ◽  
Carbonyl Compounds ◽  
Storage Time ◽  
Hydroxylamine Hydrochloride ◽  
Storage Conditions ◽  
Tobacco Product ◽  
Gas Chromatography Mass Spectrometry ◽  
Tobacco Products ◽  
Chromatography Mass Spectrometry

SUMMARY A simple, accurate, and reliable method for routine analysis of trace carbonyl compounds, including formaldehyde, acetaldehyde, acetone, propionaldehyde, methyl-ethyl ketone (MEK), butyraldehyde, and crotonaldehyde, in processed tobacco products was developed. One gram of tobacco sample was spiked with a mixture of isotopelabeled carbonyls as internal standards and extracted with water. A portion of aqueous extract was derivatizated with o-(2,3,4,5,6-pentafluorobenzyl)-hydroxylamine hydrochloride (PFBHA). The PFBHA derivatives of carbonyls were extracted with hexane and analysed by gas chromatography- mass spectrometry (GC-MS). The accuracy and precision of the method were evaluated with spiked Kentucky Reference Cigarette 3R4F and CORESTA smokeless reference products CRP1, CRP2, CRP3, and CRP4. For the investigated carbonyl compounds, excellent recoveries (95-107%) and precisions (5-10%) were achieved with different spiked tobacco products, with the exception of acrolein, which was found unstable in all tested tobacco products. The linear range of the developed method was from 0.07 to 36 μg/g with limits of quantification ranged from 0.10 to 0.15 μg/g. Using this method, formaldehyde (0.31-6.24 μg/g) and acetaldehyde (0.84-17.7 μg/g) were detected in all tested reference tobacco products. Acetone (0.55-2.12 μg/g) was found in 3R4F, CRP1, CRP2, and CRP3. Detectable levels of propionaldehyde were only found in CRP1 and CRP3. The levels of MEK, butyraldehyde, and crotonaldehyde in all tested reference products were below the method quantification limits. It was found that the effects of storage conditions (storage time, container, and temperature) on yields of carbonyls detected in reference tobacco product samples (3R4F, CRP2, CRP3) were dependent on compound and sample matrix: the concentrations of formaldehyde in all tested reference products gradually increased as the storage time increased, while the concentrations of acetone in 3R4F samples dramatically decreased as the storage time increased. [Beitr. Tabakforsch. Int. 26 (2014) 86-97]

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