scholarly journals Development of a flat membrane based device for electromembrane extraction: A new approach for exhaustive extraction of basic drugs from human plasma

2014 ◽  
Vol 1326 ◽  
pp. 7-12 ◽  
Author(s):  
Chuixiu Huang ◽  
Lars Erik Eng Eibak ◽  
Astrid Gjelstad ◽  
Xiantao Shen ◽  
Roger Trones ◽  
...  
Keyword(s):  
Human Plasma ◽  
Basic Drugs ◽  
New Approach ◽  
Electromembrane Extraction ◽  
Exhaustive Extraction ◽  
Flat Membrane

Exhaustive extraction of peptides by electromembrane extraction

2015 ◽  
Vol 853 ◽  
pp. 328-334 ◽  
Author(s):  
Chuixiu Huang ◽  
Astrid Gjelstad ◽  
Stig Pedersen-Bjergaard
Keyword(s):  
Electromembrane Extraction ◽  
Exhaustive Extraction

Exhaustive and stable electromembrane extraction of acidic drugs from human plasma

2015 ◽  
Vol 1425 ◽  
pp. 81-87 ◽  
Author(s):  
Chuixiu Huang ◽  
Astrid Gjelstad ◽  
Knut Fredrik Seip ◽  
Henrik Jensen ◽  
Stig Pedersen-Bjergaard
Keyword(s):  
Human Plasma ◽  
Acidic Drugs ◽  
Electromembrane Extraction

New approach for measurement of non-SHBG-bound testosterone in human plasma

2010 ◽  
Vol 658 (1) ◽  
pp. 87-90 ◽  
Author(s):  
Véronique Raverot ◽  
Jonathan Lopez ◽  
Catherine Grenot ◽  
Michel Pugeat ◽  
Henri Déchaud
Keyword(s):  
Human Plasma ◽  
New Approach

scholarly journals Undulating changes in human plasma proteome across lifespan are linked to disease

2019 ◽  
Author(s):  
Benoit Lehallier ◽  
David Gate ◽  
Nicholas Schaum ◽  
Tibor Nanasi ◽  
Song Eun Lee ◽  
...  
Keyword(s):  
Human Plasma ◽  
Plasma Proteins ◽  
Biological Pathways ◽  
Phenotypic Traits ◽  
Plasma Proteome ◽  
New Approach ◽  
Disease Biology ◽  
Age Related ◽  
Insight Into ◽  
Human Plasma Proteome

Aging is the predominant risk factor for numerous chronic diseases that limit healthspan. Mechanisms of aging are thus increasingly recognized as therapeutic targets. Blood from young mice reverses aspects of aging and disease across multiple tissues, pointing to the intriguing possibility that age-related molecular changes in blood can provide novel insight into disease biology. We measured 2,925 plasma proteins from 4,331 young adults to nonagenarians and developed a novel bioinformatics approach which uncovered profound non-linear alterations in the human plasma proteome with age. Waves of changes in the proteome in the fourth, seventh, and eighth decades of life reflected distinct biological pathways, and revealed differential associations with the genome and proteome of age-related diseases and phenotypic traits. This new approach to the study of aging led to the identification of unexpected signatures and pathways of aging and disease and offers potential pathways for aging interventions.

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