412 Validation of a novel clinical outcome score: Predicting the sequelae of infant heart surgery

2011 ◽  
Vol 27 (5) ◽  
pp. S210-S211
Author(s):  
A.S. Mackie ◽  
G.Y. Alton ◽  
I. Dinu ◽  
A.R. Joffe ◽  
S.J. Roth ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Heart Surgery ◽  
Clinical Outcome Score ◽  
Outcome Score

Clinical Outcome Score Predicts Adverse Neurodevelopmental Outcome After Infant Heart Surgery

2015 ◽  
Vol 99 (6) ◽  
pp. 2124-2132 ◽  
Author(s):  
Andrew S. Mackie ◽  
Shabnam Vatanpour ◽  
Gwen Y. Alton ◽  
Irina A. Dinu ◽  
Lindsay Ryerson ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Heart Surgery ◽  
Neurodevelopmental Outcome ◽  
Clinical Outcome Score ◽  
Outcome Score

A NOVEL CLINICAL OUTCOME SCORE: PREDICTING THE SEQUELAE OF INFANT HEART SURGERY

2006 ◽  
Vol 7 (Supplement) ◽  
pp. S26
Author(s):  
Vamsi Yarlagadda ◽  
David Wypij ◽  
Peter Laussen ◽  
Stephen Roth ◽  
Andrew Mackie ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Heart Surgery ◽  
Clinical Outcome Score ◽  
Outcome Score

scholarly journals Clinical outcome score predicts the need for neurodevelopmental intervention after infant heart surgery

2013 ◽  
Vol 145 (5) ◽  
pp. 1248-1254.e2 ◽  
Author(s):  
Andrew S. Mackie ◽  
Gwen Y. Alton ◽  
Irina A. Dinu ◽  
Ari R. Joffe ◽  
Stephen J. Roth ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Heart Surgery ◽  
Clinical Outcome Score ◽  
Outcome Score

scholarly journals CLINICAL OUTCOME SCORE PREDICTS ADVERSE NEURODEVELOPMENTAL OUTCOME AFTER INFANT HEART SURGERY

2014 ◽  
Vol 30 (10) ◽  
pp. S173-S174
Author(s):  
A.S. Mackie ◽  
S. Vatanpour ◽  
G.Y. Alton ◽  
I.A. Dinu ◽  
L. Ryerson ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Heart Surgery ◽  
Neurodevelopmental Outcome ◽  
Clinical Outcome Score ◽  
Outcome Score

The Correlation of a Sarcoidosis Clinical Outcome Score to Patient Demographics and Sarcoidosis Organ Involvement

2019 ◽  
Author(s):  
K. Hu ◽  
R. Reeves ◽  
J.M. Zeigler ◽  
M.A. Judson ◽  
D.A. Culver ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Organ Involvement ◽  
Patient Demographics ◽  
Clinical Outcome Score ◽  
Outcome Score

Effect of hyperbaric oxygen therapy and corticosteroid therapy in military personnel with acute acoustic trauma

2019 ◽  
pp. jramc-2018-001117 ◽  
Author(s):  
A B Bayoumy ◽  
E L van der Veen ◽  
P-J A M van Ooij ◽  
F S Besseling-Hansen ◽  
D A A Koch ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Corticosteroid Therapy ◽  
Hyperbaric Oxygen ◽  
Military Personnel ◽  
Hyperbaric Oxygen Therapy ◽  
Oxygen Therapy ◽  
Acoustic Trauma ◽  
T Test ◽  
Clinical Outcome Score ◽  
Acute Acoustic Trauma

IntroductionAcute acoustic trauma (AAT) is a sensorineural hearing impairment due to exposure to an intense impulse noise which causes cochlear hypoxia. Hyperbaric oxygen therapy (HBO) could provide an adequate oxygen supply. The aim was to investigate the effectiveness of early treatment with combined HBO and corticosteroid therapy in patients with AAT compared with corticosteroid monotherapy.MethodsA retrospective study was performed on military personnel diagnosed with AAT between November 2012 and December 2017. Inclusion criteria for HBO therapy were hearing loss of 30 dB or greater on at least one, 25 dB or more on at least two, or 20 dB or more on three or more frequencies as compared with the contralateral ear.ResultsAbsolute hearing improvements showed significant differences (independent t-test) between patients receiving HBO and the control group at 500 Hz (p=0.014), 3000 Hz (p=0.023), 4000 Hz (p=0.001) and 6000 Hz (p=0.01) and at the mean of all frequencies (p=0.002). Relative hearing improvements were significantly different (independent t-test) at 4000 Hz (p=0.046) and 6000 Hz (p=0.013) and at all frequencies combined (p=0.005). Furthermore, the percentage of patients with recovery to the functional level required by the Dutch Armed Forces (clinical outcome score) was higher in the HBO group.ConclusionsEarly-stage combination therapy for patients with AAT was associated with better audiometric results at higher frequencies and better clinical outcome score.

Pathology‐Related Differences in Cardiac Troponin I and Clinical Outcome After Paediatric Open‐Heart Surgery

2002 ◽  
Vol 17 (6) ◽  
pp. 561-561 ◽  
Author(s):  
P Modi ◽  
H Imura ◽  
M Caputo ◽  
AJ Parry ◽  
A Pawade* ◽  
...  
Keyword(s):  
Clinical Outcome ◽  
Cardiac Troponin ◽  
Heart Surgery ◽  
Troponin I ◽  
Open Heart Surgery ◽  
Cardiac Troponin I ◽  
Open Heart

PRE-OPERATIVE AND POST-OPERATIVE C-REACTIVE PROTEIN LEVELS CORRELATE WITH CLINICAL OUTCOME FOLLOWING INFANT HEART SURGERY WITH CARDIOPULMONARY BYPASS

2005 ◽  
Vol 6 (3) ◽  
pp. 389
Author(s):  
Catherine K. Allan ◽  
Jane W. Newburger ◽  
Ellen McGrath ◽  
Jodi Elder ◽  
Charles Psoinos ◽  
...  
Keyword(s):  
Cardiopulmonary Bypass ◽  
Clinical Outcome ◽  
Heart Surgery ◽  
C Reactive Protein ◽  
Protein Levels ◽  
Reactive Protein

Effect of modified ultrafiltration on the inflammatory response in paediatric open-heart surgery: a prospective, randomized study

Perfusion ◽  
2002 ◽  
Vol 17 (5) ◽  
pp. 327-333 ◽  
Author(s):  
Michelle S Chew ◽  
Vibeke Brix-Christensen ◽  
Hanne B Ravn ◽  
Ivan Brandslund ◽  
Emmy Ditlevsen ◽  
...  
Keyword(s):  
Cardiac Surgery ◽  
Clinical Outcome ◽  
Heart Surgery ◽  
Randomized Study ◽  
Open Heart Surgery ◽  
Coagulation System ◽  
Arterial Oxygen ◽  
Markers Of Inflammation ◽  
Postoperative Oxygenation ◽  
To Receive

Modified ultrafiltration (MUF) is often used in conjunction with paediatric cardiac surgery with cardiopulmonary bypass (CPB) and is thought to improve clinical outcome. It is unclear whether these improvements (if any) are due to the removal of inflammatory mediators. In this prospective study, 18 children aged 12-24 months undergoing uncomplicated cardiac surgery with methylprednisolone added in the pump prime were randomized to receive CPB with ( n= 10) and without ( n= 8) MUF. Cytokines (TNFα, IL-6, IL- 1β, IL-10, IL-1ra), complement split products (C3d, C4d) and coagulation system activation (F1+ 2, ATIII) were measured pre-, peri- and up to 48 h postoperatively. For clinical outcome, the alveolar-arterial oxygen (A-a) gradient, transfusion requirement, drain loss, mean blood pressure and requirement for inotropic support were registered up to 24 h postoperatively. Our results show an improvement in postoperative oxygenation as well as a tendency towards decreased drain loss and improved haemodynamics in the MUF group. There were no intergroup differences detectable for TNFα, IL-1β, IL-1ra, complement and coagulation markers. We conclude that MUF in itself does not significantly influence TNFα, IL-1β, IL-1ra and the complement and coagulation profiles in children undergoing cardiac surgerywith CPB. Despite this, there was some evidence for improved clinical outcome. Our results do not support that MUF improves postoperative organ function by modulation of the measured markers of inflammation.

Effect of Methylprednisolone on the Oxidative Burst Activity, Adhesion Molecules and Clinical Outcome Following Open Heart Surgery

1997 ◽  
Vol 31 (5) ◽  
pp. 283-288 ◽  
Author(s):  
P. Toft ◽  
K. Christiansen ◽  
E. Tønnesen ◽  
C. H. Nielsen ◽  
S. Lillevang
Keyword(s):  
Clinical Outcome ◽  
Adhesion Molecules ◽  
Oxidative Burst ◽  
Heart Surgery ◽  
Open Heart Surgery ◽  
Burst Activity ◽  
Open Heart ◽  
Oxidative Burst Activity
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