Drug-Induced Lupus Erythematosus Presenting With Cardiac Tamponade: A Case Report and Literature Review

2014 ◽  
Vol 30 (2) ◽  
pp. 247.e11-247.e12 ◽  
Author(s):  
David T. Harnett ◽  
Harnahalli B. Chandra-Sekhar ◽  
Sean F. Hamilton
2017 ◽  
Vol 2017 ◽  
pp. 1-3 ◽  
Author(s):  
Vicken Zeitjian ◽  
Azar Mehdizadeh

This case describes a patient with pericardial effusion as a phenomenon of the drug-induced lupus erythematosus (DILE) syndrome due to hydralazine. The relevance of this case report lies in the fact that although hydralazine has been a known causative agent of DILE, its presentation may involve a negative anti-nuclear antibody (ANA) study. Pericardial effusion is a documented adverse effect as a result of hydralazine use. It is typically common to screen for DILE with the serum ANA test prior to proceeding to more costly and specific tests (i.e., anti-histone antibody). As per our literature review, this is the second case of hydralazine causing DILE with a negative ANA. As in our case, although the screening serum ANA is the initial next best step for suspicion of DILE by hydralazine, it is important to consider the diagnosis without ANA positivity.


2013 ◽  
Vol 25 (4) ◽  
pp. 642-645 ◽  
Author(s):  
Marta Mosca ◽  
Chiara Tani ◽  
Maria Elena Filice ◽  
Linda Carli ◽  
Andrea Delle Sedie ◽  
...  

2021 ◽  
Vol 13 (3) ◽  
pp. 109-112
Author(s):  
Parviz Torkzaban ◽  
Amir Talaie

Systemic lupus erythematosus is a systemic autoimmune disease that involves multi organs. Genetic, endocrine, immunological, and environmental factors influence the loss of immunological tolerance against self-antigens leading to the formation of pathogenic autoantibodies that cause tissue damage through multiple mechanisms. The gingival overgrowth can be caused by three factors: noninflammatory, hyperplastic reaction to the medication; chronic inflammatory hyperplasia; or a combined enlargement due to chronic inflammation and drug-induced hyperplasia. Drug-Induced Gingival Overgrowth is associated with the use of three major classes of drugs, namely anticonvulsants, calcium channel blockers, and immunosuppressants. Due to recent indications for these drugs, their use continues to grow.


2008 ◽  
Vol 18 (5) ◽  
pp. 511-515 ◽  
Author(s):  
Mitsuteru Akahoshi ◽  
Kumiko Aizawa ◽  
Shuji Nagano ◽  
Hisako Inoue ◽  
Atsushi Sadanaga ◽  
...  

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