P188 Inducing motor cortical plasticity in Parkinson’s disease using subthalamic deep brain stimulation and repetitive transcranial magnetic stimulation

2020 ◽  
Vol 131 (4) ◽  
pp. e121
Author(s):  
C. Rinchon ◽  
C.A. Gunraj ◽  
N.M. Drummond ◽  
T. Hoque ◽  
U. Saha ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Deep Brain Stimulation ◽  
Transcranial Magnetic Stimulation ◽  
Brain Stimulation ◽  
Magnetic Stimulation ◽  
Cortical Plasticity ◽  
Repetitive Transcranial Magnetic Stimulation ◽  
Motor Cortical ◽  
Deep Brain

Neuromodulation Approaches in Parkinson’s Disease Using Deep Brain Stimulation and Transcranial Magnetic Stimulation

2021 ◽  
Vol 34 (4) ◽  
pp. 301-309 ◽  
Author(s):  
Ryan T. Cleary ◽  
Richard Bucholz
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Deep Brain Stimulation ◽  
Transcranial Magnetic Stimulation ◽  
Brain Stimulation ◽  
Magnetic Stimulation ◽  
Psychiatric Disease ◽  
Motor Symptoms ◽  
Ongoing Research ◽  
Deep Brain

Parkinson’s Disease (PD) is the second most common neurodegenerative disease, characterized by progressive motor (such as resting tremor, hypokinesia, postural instability) and non-motor symptoms (such as neuropsychiatric decline and autonomic dysfunction). Since its introduction in the late 1980s, deep brain stimulation (DBS) has revolutionized the treatment of PD. Initially used in patients’ with advanced PD with either medically refractory motor symptoms or medication intolerance, DBS typically provides excellent improvement in motor symptoms. Indications for DBS have continued to expand, with demonstrated efficacy in early PD and essential tremor, and promising preliminary results in the treatment of epilepsy, psychiatric disease, and depression. Advancements in DBS hardware, programming, neuroimaging, and surgical techniques have led to progressive improvement in efficacy and safety profiles. Thanks to ongoing research into remote programming, adaptive DBS, new targets, and alternative interventions, such as transcranial magnetic stimulation, the opportunities for further improvements in DBS and neuromodulation are bright.

Influence of deep brain stimulation and levodopa on signs and symptoms in Parkinson's disease

2009 ◽  
Vol 36 (S 02) ◽  
Author(s):  
J Gierthmühlen ◽  
P Arning ◽  
G Wasner ◽  
A Binder ◽  
J Herzog ◽  
...  
Keyword(s):  
Parkinson’S Disease ◽  
Parkinson's Disease ◽  
Deep Brain Stimulation ◽  
Brain Stimulation ◽  
Signs And Symptoms ◽  
Deep Brain
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