Two multicenter, 8-week, randomized, double-blind, placebo-controlled, parallel-group studies evaluating the efficacy and tolerability of amlodipine and valsartan in combination and as monotherapy in adult patients with mild to moderate essential hypertension

Thomas Philipp; Timothy R. Smith; Robert Glazer; Margaret Wernsing; Joseph Yen; James Jin; Helmut Schneider; Rainer Pospiech

doi:10.1016/j.clinthera.2007.03.018

Two multicenter, 8-week, randomized, double-blind, placebo-controlled, parallel-group studies evaluating the efficacy and tolerability of amlodipine and valsartan in combination and as monotherapy in adult patients with mild to moderate essential hypertension

Clinical Therapeutics ◽

10.1016/j.clinthera.2007.03.018 ◽

2007 ◽

Vol 29 (4) ◽

pp. 563-580 ◽

Cited By ~ 186

Author(s):

Thomas Philipp ◽

Timothy R. Smith ◽

Robert Glazer ◽

Margaret Wernsing ◽

Joseph Yen ◽

...

Keyword(s):

Essential Hypertension ◽

Moderate Essential Hypertension ◽

Adult Patients ◽

Double Blind ◽

Double Blind Placebo ◽

Parallel Group

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Evaluation of the Efficacy and Tolerability of Combination Therapy With Candesartan Cilexetil and Amlodipine Besilate Compared With Candesartan Cilexetil Monotherapy and Amlodipine Besilate Monotherapy in Japanese Patients With Mild-to-Moderate Essential Hypertension: A Multicenter, 12-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study

Clinical Therapeutics ◽

10.1016/j.clinthera.2012.02.015 ◽

2012 ◽

Vol 34 (4) ◽

pp. 838-848 ◽

Cited By ~ 5

Author(s):

Hiromi Rakugi ◽

Toshio Ogihara ◽

Yuko Miyata ◽

Kiyofumi Sasai ◽

Nobuo Totsuka

Keyword(s):

Essential Hypertension ◽

Combination Therapy ◽

Candesartan Cilexetil ◽

Japanese Patients ◽

Moderate Essential Hypertension ◽

Double Blind ◽

Double Blind Placebo ◽

Parallel Group Study ◽

Parallel Group

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A twelve-week, multicenter, randomized, double-blind, parallel-group, noninferiority trial of the antihypertensive efficacy and tolerability of imidapril and candesartan in adult patients with mild to moderate essential hypertension: The Iberian Multicenter Imidapril study on hypertension (IMISH)

Clinical Therapeutics ◽

10.1016/j.clinthera.2006.12.006 ◽

2006 ◽

Vol 28 (12) ◽

pp. 2040-2051 ◽

Cited By ~ 9

Author(s):

Jose Luis Palma Gámiz ◽

Mariano Pêgo ◽

Emilio Márquez Contreras ◽

Montserrat Pujol Anglada ◽

Josefina Oliván Martinez ◽

...

Keyword(s):

Essential Hypertension ◽

Moderate Essential Hypertension ◽

Antihypertensive Efficacy ◽

Adult Patients ◽

Double Blind ◽

Noninferiority Trial ◽

Parallel Group

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Efficacy and tolerability of nebivolol monotherapy by baseline systolic blood pressure: A retrospective analysis of pooled data from two multicenter, 12-week, randomized, double-blind, placebo-controlled, parallel-group, dose-ranging studies in patients with mild to moderate essential hypertension

Clinical Therapeutics ◽

10.1016/j.clinthera.2009.08.028 ◽

2009 ◽

Vol 31 (9) ◽

pp. 1946-1956 ◽

Cited By ~ 2

Author(s):

F. Wilford Germino

Keyword(s):

Blood Pressure ◽

Essential Hypertension ◽

Systolic Blood Pressure ◽

Moderate Essential Hypertension ◽

Double Blind ◽

Double Blind Placebo ◽

Pooled Data ◽

Parallel Group ◽

Baseline Systolic Blood Pressure ◽

Dose Ranging

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A Randomized, Double-blind, Candesartan-controlled, Parallel Group Comparison Clinical Trial to Evaluate the Antihypertensive Efficacy and Safety of Fimasartan in Patients with Mild to Moderate Essential Hypertension

Clinical Therapeutics ◽

10.1016/j.clinthera.2016.04.005 ◽

2016 ◽

Vol 38 (6) ◽

pp. 1485-1497 ◽

Cited By ~ 6

Author(s):

Jang Hoon Lee ◽

Dong Heon Yang ◽

Jin Yong Hwang ◽

Seung Ho Hur ◽

Tae Joon Cha ◽

...

Keyword(s):

Clinical Trial ◽

Essential Hypertension ◽

Moderate Essential Hypertension ◽

Antihypertensive Efficacy ◽

Group Comparison ◽

Efficacy And Safety ◽

Double Blind ◽

Parallel Group

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Comparison of efficacy and tolerability of amlodipine orotate versus amlodipine besylate in adult patients with mild to moderate hypertension: A multicenter, randomized, double-blind, placebo-controlled, parallel-group, 8-week follow-up, noninferiority trial

Clinical Therapeutics ◽

10.1016/j.clinthera.2006.04.008 ◽

2006 ◽

Vol 28 (4) ◽

pp. 537-551 ◽

Cited By ~ 9

Author(s):

Soon Jun Hong ◽

Tae-Noon Ahn ◽

Sang-Hong Baek ◽

Wook-Hyun Cho ◽

Hyee-Kyoung Jeon ◽

...

Keyword(s):

Moderate Hypertension ◽

Adult Patients ◽

Amlodipine Besylate ◽

Double Blind ◽

Double Blind Placebo ◽

Noninferiority Trial ◽

Parallel Group

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Low-dose clonidine administration in the treatment of mild or moderate essential hypertension: results from a double-blind placebo-controlled study (Clobass)

Journal of Hypertension ◽

10.1097/00004872-199006000-00007 ◽

1990 ◽

Vol 8 (6) ◽

pp. 539-546 ◽

Cited By ~ 3

Author(s):

&NA; &NA;

Keyword(s):

Essential Hypertension ◽

Low Dose ◽

Moderate Essential Hypertension ◽

Controlled Study ◽

Double Blind ◽

Double Blind Placebo

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Ambulatory Blood Pressure Response to Once-Daily Fimasartan: An 8-Week, Multicenter, Randomized, Double-Blind, Active-Comparator, Parallel-Group Study in Korean Patients With Mild To Moderate Essential Hypertension

Clinical Therapeutics ◽

10.1016/j.clinthera.2013.06.021 ◽

2013 ◽

Vol 35 (9) ◽

pp. 1337-1349 ◽

Cited By ~ 17

Author(s):

Howard Lee ◽

Kee Sik Kim ◽

Shung Chull Chae ◽

Myung Ho Jeong ◽

Dong-Soo Kim ◽

...

Keyword(s):

Blood Pressure ◽

Essential Hypertension ◽

Ambulatory Blood Pressure ◽

Blood Pressure Response ◽

Moderate Essential Hypertension ◽

Double Blind ◽

Once Daily ◽

Active Comparator ◽

Korean Patients ◽

Parallel Group

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Effect of Fimasartan versus Valsartan and Olmesartan on Office and Ambulatory Blood Pressure in Korean Patients with Mild-to-Moderate Essential Hypertension: A Randomized, Double-Blind, Active Control, Three-Parallel Group, Forced Titration, Multicenter, Phase IV Study (Fimasartan Achieving Systolic Blood Pressure Target (FAST) Study)

Drug Design Development and Therapy ◽

10.2147/dddt.s231293 ◽

2020 ◽

Vol Volume 14 ◽

pp. 347-360

Author(s):

Woo-Baek Chung ◽

Sang-Hyun Ihm ◽

Sung-Won Jang ◽

Sung-Ho Her ◽

Chul Soo Park ◽

...

Keyword(s):

Blood Pressure ◽

Essential Hypertension ◽

Systolic Blood Pressure ◽

Active Control ◽

Ambulatory Blood Pressure ◽

Moderate Essential Hypertension ◽

Blood Pressure Target ◽

Double Blind ◽

Multicenter Phase ◽

Parallel Group

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Doxazosin for the Treatment of Benign Prostatic Hyperplasia in Patients with Mild to Moderate Essential Hypertension: A Double-Blind, Placebo-Controlled, Dose-Response Multicenter Study

The Journal of Urology ◽

10.1016/s0022-5347(01)67243-4 ◽

1995 ◽

Vol 154 (1) ◽

pp. 110-115 ◽

Cited By ~ 121

Author(s):

Jay Y. Gillenwater ◽

Richard L. Conn ◽

Steven G. Chrysant ◽

Johnny Roy ◽

Michael Gaffney ◽

...

Keyword(s):

Essential Hypertension ◽

Benign Prostatic Hyperplasia ◽

Dose Response ◽

Multicenter Study ◽

Moderate Essential Hypertension ◽

Prostatic Hyperplasia ◽

Double Blind ◽

Double Blind Placebo

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A randomized, double‐blind, placebo‐controlled, multicenter, parallel‐group study to evaluate the efficacy and safety of adjunctive brivaracetam in adult patients with uncontrolled partial‐onset seizures

Epilepsia ◽

10.1111/epi.13212 ◽

2015 ◽

Vol 56 (12) ◽

pp. 1890-1898 ◽

Cited By ~ 112

Author(s):

Pavel Klein ◽

Jimmy Schiemann ◽

Michael R. Sperling ◽

John Whitesides ◽

Wei Liang ◽

...

Keyword(s):

Adult Patients ◽

Efficacy And Safety ◽

Double Blind ◽

Double Blind Placebo ◽

Parallel Group Study ◽

Parallel Group

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