Evaluation of the Efficacy and Tolerability of Combination Therapy With Candesartan Cilexetil and Amlodipine Besilate Compared With Candesartan Cilexetil Monotherapy and Amlodipine Besilate Monotherapy in Japanese Patients With Mild-to-Moderate Essential Hypertension: A Multicenter, 12-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study

Hiromi Rakugi; Toshio Ogihara; Yuko Miyata; Kiyofumi Sasai; Nobuo Totsuka

doi:10.1016/j.clinthera.2012.02.015

Evaluation of the Efficacy and Tolerability of Combination Therapy With Candesartan Cilexetil and Amlodipine Besilate Compared With Candesartan Cilexetil Monotherapy and Amlodipine Besilate Monotherapy in Japanese Patients With Mild-to-Moderate Essential Hypertension: A Multicenter, 12-Week, Randomized, Double-Blind, Placebo-Controlled, Parallel-Group Study

Clinical Therapeutics ◽

10.1016/j.clinthera.2012.02.015 ◽

2012 ◽

Vol 34 (4) ◽

pp. 838-848 ◽

Cited By ~ 5

Author(s):

Hiromi Rakugi ◽

Toshio Ogihara ◽

Yuko Miyata ◽

Kiyofumi Sasai ◽

Nobuo Totsuka

Keyword(s):

Essential Hypertension ◽

Combination Therapy ◽

Candesartan Cilexetil ◽

Japanese Patients ◽

Moderate Essential Hypertension ◽

Double Blind ◽

Double Blind Placebo ◽

Parallel Group Study ◽

Parallel Group

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A randomized, double-blind, four-arm parallel-group study of the efficacy and safety of azelnidipine and olmesartan medoxomil combination therapy compared with each monotherapy in Japanese patients with essential hypertension: the REZALT study

Hypertension Research ◽

10.1038/hr.2009.163 ◽

2009 ◽

Vol 32 (12) ◽

pp. 1148-1154 ◽

Cited By ~ 32

Author(s):

Toshio Ogihara ◽

Takao Saruta ◽

Kazuyuki Shimada ◽

Kizuku Kuramoto

Keyword(s):

Essential Hypertension ◽

Combination Therapy ◽

Olmesartan Medoxomil ◽

Japanese Patients ◽

Efficacy And Safety ◽

Double Blind ◽

Parallel Group Study ◽

Parallel Group

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Two multicenter, 8-week, randomized, double-blind, placebo-controlled, parallel-group studies evaluating the efficacy and tolerability of amlodipine and valsartan in combination and as monotherapy in adult patients with mild to moderate essential hypertension

Clinical Therapeutics ◽

10.1016/j.clinthera.2007.03.018 ◽

2007 ◽

Vol 29 (4) ◽

pp. 563-580 ◽

Cited By ~ 186

Author(s):

Thomas Philipp ◽

Timothy R. Smith ◽

Robert Glazer ◽

Margaret Wernsing ◽

Joseph Yen ◽

...

Keyword(s):

Essential Hypertension ◽

Moderate Essential Hypertension ◽

Adult Patients ◽

Double Blind ◽

Double Blind Placebo ◽

Parallel Group

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Gabapentin enacarbil in Japanese patients with restless legs syndrome: a 12-week, randomized, double-blind, placebo-controlled, parallel-group study

Current Medical Research and Opinion ◽

10.1185/03007995.2012.746217 ◽

2012 ◽

Vol 29 (1) ◽

pp. 13-21 ◽

Cited By ~ 22

Author(s):

Yuichi Inoue ◽

Koichi Hirata ◽

Naohisa Uchimura ◽

Kenji Kuroda ◽

Nobutaka Hattori ◽

...

Keyword(s):

Restless Legs Syndrome ◽

Japanese Patients ◽

Gabapentin Enacarbil ◽

Double Blind ◽

Double Blind Placebo ◽

Restless Legs ◽

Parallel Group Study ◽

Parallel Group

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Efficacy and tolerability of nebivolol monotherapy by baseline systolic blood pressure: A retrospective analysis of pooled data from two multicenter, 12-week, randomized, double-blind, placebo-controlled, parallel-group, dose-ranging studies in patients with mild to moderate essential hypertension

Clinical Therapeutics ◽

10.1016/j.clinthera.2009.08.028 ◽

2009 ◽

Vol 31 (9) ◽

pp. 1946-1956 ◽

Cited By ~ 2

Author(s):

F. Wilford Germino

Keyword(s):

Blood Pressure ◽

Essential Hypertension ◽

Systolic Blood Pressure ◽

Moderate Essential Hypertension ◽

Double Blind ◽

Double Blind Placebo ◽

Pooled Data ◽

Parallel Group ◽

Baseline Systolic Blood Pressure ◽

Dose Ranging

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Comparison of the antihypertensive effect of imidapril and enalapril in the treatment of mild to moderate essential hypertension: a randomized, double-blind, parallel-group study

Current Therapeutic Research ◽

10.1016/s0011-393x(01)80055-2 ◽

2001 ◽

Vol 62 (6) ◽

pp. 437-450 ◽

Cited By ~ 1

Author(s):

Reinhard van der Does ◽

Rolf Euler

Keyword(s):

Essential Hypertension ◽

Antihypertensive Effect ◽

Moderate Essential Hypertension ◽

Double Blind ◽

Parallel Group Study ◽

Parallel Group

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Effects of Tolvaptan on Volume Overload in Japanese Patients with Heart Failure: Results of a Phase II, Multicenter, Randomized, Double-blind, Placebo-controlled, Parallel-group Study

Cardiovascular Drugs and Therapy ◽

10.1007/s10557-011-6303-y ◽

2011 ◽

Vol 25 (S1) ◽

pp. 19-31 ◽

Cited By ~ 29

Author(s):

Masunori Matsuzaki ◽

◽

Masatsugu Hori ◽

Tohru Izumi ◽

Hidetsugu Asanoi ◽

...

Keyword(s):

Heart Failure ◽

Phase Ii ◽

Volume Overload ◽

Japanese Patients ◽

Double Blind ◽

Double Blind Placebo ◽

Parallel Group Study ◽

Parallel Group ◽

Patients With Heart Failure

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A Randomized, Double-Blind, Parallel-Group Study to Compare the Anti-Hypertensive Effects of Imidapril and Nifedipine in the Treatment of Mild-to-Moderate Essential Hypertension

Journal of International Medical Research ◽

10.1177/147323000102900302 ◽

2001 ◽

Vol 29 (3) ◽

pp. 154-162 ◽

Cited By ~ 7

Author(s):

R van der Does ◽

R Euler

Keyword(s):

Essential Hypertension ◽

Moderate Essential Hypertension ◽

Double Blind ◽

Parallel Group Study ◽

Parallel Group

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A 24-week, multicenter, randomized, double-blind, placebo-controlled, parallel-group study of the efficacy and tolerability of combination therapy with rosiglitazone and sulfonylurea in african american and hispanic american patients with type 2 diabetes inadequately controlled with sulfonylurea monotherapy

Clinical Therapeutics ◽

10.1016/j.clinthera.2007.09.011 ◽

2007 ◽

Vol 29 (9) ◽

pp. 1900-1914 ◽

Cited By ~ 20

Author(s):

J DAVIDSON ◽

S MCMORN ◽

B WATERHOUSE ◽

A COBITZ

Keyword(s):

Type 2 Diabetes ◽

African American ◽

Combination Therapy ◽

Hispanic American ◽

Double Blind ◽

Double Blind Placebo ◽

Parallel Group Study ◽

Parallel Group

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Nifedipine controlled-release 40 mg b.i.d. in Japanese patients with essential hypertension who responded insufficiently to nifedipine controlled-release 40 mg q.d.: a phase III, randomized, double-blind and parallel-group study

Hypertension Research ◽

10.1038/hr.2013.80 ◽

2013 ◽

Vol 37 (1) ◽

pp. 69-75 ◽

Cited By ~ 227

Author(s):

Kazuaki Shimamoto ◽

Naoyuki Hasebe ◽

Sadayoshi Ito ◽

Kazuomi Kario ◽

Kenjiro Kimura ◽

...

Keyword(s):

Essential Hypertension ◽

Controlled Release ◽

Japanese Patients ◽

Phase Iii ◽

Double Blind ◽

Parallel Group Study ◽

Parallel Group

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A randomised, double-blind, placebo controlled, parallel group study of the standardised extract SHR-5 of the roots of Rhodiola rosea in the treatment of subjects with stress-related fatigue

Planta Medica ◽

10.1055/s-0029-1235006 ◽

2009 ◽

Vol 75 (09) ◽

Cited By ~ 2

Author(s):

EMG Olsson ◽

B von Schéele ◽

AG Panossian

Keyword(s):

Rhodiola Rosea ◽

Double Blind ◽

Double Blind Placebo ◽

Parallel Group Study ◽

Parallel Group

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