scholarly journals Double hit strategy using pH-sensitive liposomes containing doxorubicin and pheophorbide-a for combination tumor therapy

2022 ◽  
Vol 46 ◽  
pp. 100565
Author(s):  
Eunyoung Park ◽  
Donghyun Lee ◽  
Yeeun Lee ◽  
Eunjin Jeong ◽  
Sehee Kim ◽  
...  
Keyword(s):  
Tumor Therapy ◽  
Ph Sensitive ◽  
Pheophorbide A ◽  
Double Hit

Biodegradable pH-sensitive prospidine-loaded dextran phosphate based hydrogels for local tumor therapy

2019 ◽  
Vol 226 ◽  
pp. 115308 ◽  
Author(s):  
Sergey O. Solomevich ◽  
Pavel M. Bychkovsky ◽  
Tatiana L. Yurkshtovich ◽  
Natalia V. Golub ◽  
Pavel Yu. Mirchuk ◽  
...  
Keyword(s):  
Tumor Therapy ◽  
Ph Sensitive ◽  
Local Tumor

Co-delivery of doxorubicin and P-glycoprotein siRNA using pH-sensitive PLGA nanobubbles for synergistic tumor therapy

2018 ◽  
Vol 14 (5) ◽  
pp. 1815
Author(s):  
Jie Yan ◽  
Hong Yang ◽  
Xue Shen ◽  
Chengchen Zhang ◽  
Chunhui Wu ◽  
...  
Keyword(s):  
Tumor Therapy ◽  
Ph Sensitive ◽  
P Glycoprotein

Gold embedded chitosan nanoparticles with cell membrane mimetic polymer coating for pH-sensitive controlled drug release and cellular fluorescence imaging

2020 ◽  
pp. 088532822095259
Author(s):  
Ke Ma ◽  
Yongbin Cheng ◽  
Xinran Wei ◽  
Daijun Chen ◽  
Xiaoli Zhao ◽  
...  
Keyword(s):  
Drug Release ◽  
Fluorescence Imaging ◽  
Colloidal Stability ◽  
Drug Loading ◽  
Tumor Therapy ◽  
Chitosan Nanoparticles ◽  
Fluorescence Emission ◽  
Controlled Drug Release ◽  
Ph Sensitive ◽  
One Pot

In this work, gold embedded chitosan nanoparticles (Au@CS NPs) were fabricated by a one-pot method. The benzaldehyde-terminated poly[(2-methacryloyloxy) ethyl phosphorylcholine] (PMPC) was applied to modification of the gold doped chitosan nanoparticles. The obtained Au@CS-PMPC NPs had the diameter of 135 nm with a narrow distribution. The size of the Au@CS-PMPC NPs, as well as the size of the embedded gold NPs, might be well-controlled by adjusting the feeding ratio between chitosan and HAuCl4. Furthermore, the Au@CS-PMPC NPs showed increased colloidal stability, high drug loading content, pH-responsive drug release, excellent biocompatibility and bright fluorescence emission. The results demonstrated that Au@CS-PMPC NPs showed a great potential for tumor therapy via the combination advantages of pH-sensitive controlled drug release and cellular fluorescence imaging.

Doxorubicin loaded pH-sensitive micelles for potential tumor therapy

2013 ◽  
Vol 172 (1) ◽  
pp. e72-e73 ◽  
Author(s):  
Wei Wu ◽  
Duo Wu ◽  
Shuai Li ◽  
Zaifu Lin, ◽  
Jianshu Li
Keyword(s):  
Tumor Therapy ◽  
Ph Sensitive

scholarly journals pH-Sensitive morphological transitions in polymeric tadpole assemblies for programmed tumor therapy

2019 ◽  
Vol 293 ◽  
pp. 1-9 ◽  
Author(s):  
Cunfeng Song ◽  
Tongtong Lin ◽  
Qiang Zhang ◽  
S. Thayumanavan ◽  
Lei Ren
Keyword(s):  
Tumor Therapy ◽  
Ph Sensitive ◽  
Morphological Transitions

CaCO3 nanoparticles pH-sensitively induce blood coagulation as a potential strategy for starving tumor therapy

2020 ◽  
Vol 8 (6) ◽  
pp. 1223-1234 ◽  
Author(s):  
Huiru Li ◽  
Xinyue Zhang ◽  
Xilin Lin ◽  
Shuqiang Zhuang ◽  
Yan Wu ◽  
...  
Keyword(s):  
Blood Coagulation ◽  
Tumor Therapy ◽  
Ph Sensitive ◽  
Tumor Vessels ◽  
Caco3 Nanoparticles ◽  
Potential Strategy

Based on the starving tumor concept, we first raised an idea that the pH-sensitive Ca2+ release of CaCO3 NPs induced blood coagulation of tumor vessels, and explored the in vitro and in vivo blood coagulation behaviors of CaCO3 NPs by acid stimulus.

A pH-responsive natural cyclopeptide RA-V drug formulation for improved breast cancer therapy

2015 ◽  
Vol 3 (22) ◽  
pp. 4514-4523 ◽  
Author(s):  
Zeng-Ying Qiao ◽  
Di Zhang ◽  
Chun-Yuan Hou ◽  
Si-Meng Zhao ◽  
Ya Liu ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Cancer Therapy ◽  
Tumor Therapy ◽  
Ph Sensitive ◽  
Drug Formulation ◽  
Ph Responsive ◽  
Breast Cancer Therapy

The co-encapsulation of RA-V cyclopeptide and SQ molecules in pH-sensitive PAE micelles for efficient tumor therapy and imaging in vitro and in vivo.

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