Segmentation-free direct tumor volume and metabolic activity estimation from PET scans

2018 ◽  
Vol 63 ◽  
pp. 52-66 ◽  
Author(s):  
Saeid Asgari Taghanaki ◽  
Noirin Duggan ◽  
Hillgan Ma ◽  
Xinchi Hou ◽  
Anna Celler ◽  
...  
Keyword(s):  
Metabolic Activity ◽  
Tumor Volume ◽  
Pet Scans ◽  
Activity Estimation

scholarly journals Dynamic Metabolic Changes during the First 3 Months after90Y-Ibritumomab Tiuxetan Radioimmunotherapy

2014 ◽  
Vol 2014 ◽  
pp. 1-6 ◽  
Author(s):  
Miwako Takahashi ◽  
Toshimitsu Momose ◽  
Keitaro Koyama ◽  
Motoshi Ichikawa ◽  
Mineo Kurokawa ◽  
...  
Keyword(s):  
Metabolic Activity ◽  
Pet Imaging ◽  
Fdg Pet ◽  
Time Course ◽  
Tumor Response ◽  
Standard Uptake Value ◽  
Metabolic Changes ◽  
Ibritumomab Tiuxetan ◽  
Before And After ◽  
Pet Scans

Objective. To elucidate the time course of tumor metabolism during the first 3 months after90Y-ibritumomab tiuxetan radioimmunotherapy (RIT) in patients with refractory malignant lymphoma.Materials and Methods. Seven patients with recurrent follicular lymphoma underwent FDG-PET imaging before and after 1-, 4-, and 12-week RIT with90Y-ibritumomab tiuxetan. Tumor metabolic activity on FDG-PET scans was assessed as the maximum standard uptake value (SUVmax).Results. Decrease in metabolism was detected 1 week after RIT. In the most decreased lesion, SUVmax decreased to 20% of the baseline value during the first week. Most lesions continued to decrease for up to 4 weeks. Some lesions showed increased metabolism from 4 to 12 weeks, while the level of FDG accumulations at 12 weeks was still lower than the baseline.Conclusions. Tumor response to RIT could be observed as early as 1 week after the administration of RIT. After tumor activity decreases, the metabolism may increase at least between 4 and 12 weeks. It suggests that the metabolic changes should be carefully evaluated during this period.

scholarly journals Relationship of EGFR Mutation to Glucose Metabolic Activity and Asphericity of Metabolic Tumor Volume in Lung Adenocarcinoma

2020 ◽  
Vol 54 (4) ◽  
pp. 175-182
Author(s):  
Wonseok Whi ◽  
Seunggyun Ha ◽  
Sungwoo Bae ◽  
Hongyoon Choi ◽  
Jin Chul Paeng ◽  
...  
Keyword(s):  
Lung Adenocarcinoma ◽  
Metabolic Activity ◽  
Tumor Volume ◽  
Egfr Mutation ◽  
Metabolic Tumor Volume ◽  
Relationship Of
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