Kinetic study of the reactions of Cl atoms with α,β-unsaturated carbonyl compounds at atmospheric pressure and structure activity relations (SARs)

2009 ◽  
Vol 479 (1-3) ◽  
pp. 25-29 ◽  
Author(s):  
Mariano A. Teruel ◽  
Mariana Achad ◽  
María B. Blanco
Keyword(s):  
Kinetic Study ◽  
Atmospheric Pressure ◽  
Carbonyl Compounds ◽  
Structure Activity ◽  
Structure Activity Relations ◽  
Cl Atoms

FTIR relative kinetic study of the reactions of CH3CH2SCH2CH3 and CH3CH2SCH3 with OH radicals and Cl atoms at atmospheric pressure

2009 ◽  
Vol 477 (1-3) ◽  
pp. 22-27 ◽  
Author(s):  
Gabriela Oksdath-Mansilla ◽  
Alicia B. Peñéñory ◽  
Mihaela Albu ◽  
Ian Barnes ◽  
Peter Wiesen ◽  
...  
Keyword(s):  
Kinetic Study ◽  
Atmospheric Pressure ◽  
Oh Radicals ◽  
Relative Kinetic ◽  
Cl Atoms

Structure-activity relations and β-lactamase resistance

1980 ◽  
Vol 289 (1036) ◽  
pp. 197-205 ◽  
Keyword(s):  
Broad Spectrum ◽  
Product Inhibition ◽  
Sulphur Atom ◽  
Chemical Modifications ◽  
Gram Negative ◽  
Structure Activity ◽  
Broad Spectrum Resistance ◽  
Structure Activity Relations ◽  
Minor Influence ◽  
A Minor

β-Lactam antibiotics resistant to β-lactamase degradation can be produced by many chemical modifications, but often at the expense of antibacterial activity. Substitution onto several positions in the molecule produces different and often selective resistance; for instance, heavily sterically hindered acyl groups give staphylococcal P-lactamase resistance to penicillins, and resistance to some enzymes from Gram-negative pathogens to both penicillins and cephalosporins. 6-α- or 7-α-substituents respectively confer a broad spectrum of resistance (e.g. cefoxitin), but changes at positions 2 or 3 have only a minor influence on enzyme susceptibility. Changes in the ring condensed with the β-lactam, such as changing ceph-3-em to ceph-2-em may greatly enhance stability. Small improvements can occur when the nuclear sulphur atom is oxidized, but a much better effect is obtained when it is replaced by another atom such as oxygen, as in clavulanic acid. This compound appears to have broad spectrum resistance which is actually due to susceptibility and subsequent product inhibition.

Kinetic Study of the Diels-Alder Reaction of Cyclopentadiene with Bis(2-Ethylhexyl) Maleate

2013 ◽  
Vol 634-638 ◽  
pp. 541-545 ◽  
Author(s):  
Jun Seong Park ◽  
Dae Hee Yun ◽  
Tae Won Ko ◽  
Yong Sung Park ◽  
Je Wan Woo
Keyword(s):  
Kinetic Study ◽  
Reaction Temperature ◽  
Atmospheric Pressure ◽  
Arrhenius Equation ◽  
Alder Reaction ◽  
Diels Alder ◽  
Influence Of Temperature ◽  
Diels Alder Reaction ◽  
Influence Of Temperature On ◽  
Kinetics Of

The kinetics of the Diels-Alder reaction of cyclopentadiene with bis(2-ethylhexyl) maleate has been studied at temperatures between 25 and 100 °C and at atmospheric pressure. The influence of temperature on the kinetic constants was determined by fitting the results to the Arrhenius equation. As a result, fitting line similar with the linear curve of the Arrhenius equation at 25, 30 and 40 °C. However, the fitting curve, at 60, 80 and 100 °C, tended towards the outside of the curve in the form of Arrhenius equation. The ratio of endo/exo was a slight change from increase of the reaction temperature.

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