scholarly journals Oral Levosimendan Increases Cerebral Blood Flow Velocities in Patients with a History of Stroke or Transient Ischemic Attack: A Pilot Safety Study

2015 ◽  
Vol 77 ◽  
pp. 46-51 ◽  
Author(s):  
Matti Kivikko ◽  
Mikko Kuoppamäki ◽  
Lauri Soinne ◽  
Stig Sundberg ◽  
Pasi Pohjanjousi ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Transient Ischemic Attack ◽  
Safety Study ◽  
History Of ◽  
Blood Flow Velocities ◽  
Ischemic Attack ◽  
Flow Velocities

Patterns of Cerebral Blood Flow and Systemic Hemodynamics During Arithmetic Processing

2008 ◽  
Vol 22 (2) ◽  
pp. 81-90 ◽  
Author(s):  
Natalie Werner ◽  
Neval Kapan ◽  
Gustavo A. Reyes del Paso
Keyword(s):  
Blood Pressure ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Time Course ◽  
Doppler Sonography ◽  
Transcranial Doppler Sonography ◽  
Systemic Hemodynamics ◽  
Heart Period ◽  
Blood Flow Velocities ◽  
Flow Velocities

The present study explored modulations in cerebral blood flow and systemic hemodynamics during the execution of a mental calculation task in 41 healthy subjects. Time course and lateralization of blood flow velocities in the medial cerebral arteries of both hemispheres were assessed using functional transcranial Doppler sonography. Indices of systemic hemodynamics were obtained using continuous blood pressure recordings. Doppler sonography revealed a biphasic left dominant rise in cerebral blood flow velocities during task execution. Systemic blood pressure increased, whereas heart period, heart period variability, and baroreflex sensitivity declined. Blood pressure and heart period proved predictive of the magnitude of the cerebral blood flow response, particularly of its initial component. Various physiological mechanisms may be assumed to be involved in cardiovascular adjustment to cognitive demands. While specific contributions of the sympathetic and parasympathetic systems may account for the observed pattern of systemic hemodynamics, flow metabolism coupling, fast neurogenic vasodilation, and cerebral autoregulation may be involved in mediating cerebral blood flow modulations. Furthermore, during conditions of high cardiovascular reactivity, systemic hemodynamic changes exert a marked influence on cerebral blood perfusion.

Longitudinal changes in cerebral blood flow velocities in different clinical courses of migraine

Cephalalgia ◽  
2016 ◽  
Vol 37 (10) ◽  
pp. 927-937 ◽  
Author(s):  
Mi Ji Lee ◽  
Min Kyung Chu ◽  
Hanna Choi ◽  
Hyun Ah Choi ◽  
Chungbin Lee ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Cerebral Artery ◽  
Posterior Cerebral Artery ◽  
Clinical Course ◽  
Episodic Migraine ◽  
Longitudinal Changes ◽  
Blood Flow Velocities ◽  
Headache Clinic ◽  
Flow Velocities

Objective To assess longitudinal changes in cerebral blood flow velocities (ΔCBFVs) according to the clinical course of migraine. Methods We retrospectively included migraine patients with two or more attacks per month at baseline who were followed up within 2 years with transcranial Doppler in a tertiary headache clinic. ΔCBFVs were analyzed in relation to clinical courses, defined as remission (0–1 headache days/month), persistence (2–14/month), or progression (≥15/month) in episodic migraine (EM), and conversion to EM (<15/month) and persistence (≥15/month) in chronic migraine (CM). Results A total of 166 patients (90 EM and 76 CM) were included. In EM, the remission group ( n = 30) showed a decrease in CBFV in the middle cerebral artery (MCA) and the basilar artery (BA). The progression group ( n = 10) showed increasing CBFVs in the bilateral MCAs. Patients with the persistence course ( n = 50) showed generally unchanged CBFVs. In CM, ΔCBFVs decreased in the BA and increased in the posterior cerebral artery (PCA) after conversion to EM ( n = 61), whereas they remained unchanged in the persistence group ( n = 15). In all patients, % change in headache days was positively correlated with the %ΔCBFVs of the bilateral MCAs and the BA. Conclusions CBFV changes are associated with the different clinical courses of migraine. The association is more prominent in EM than CM.

scholarly journals Cerebral blood flow velocities and cerebrovascular resistance in normal-term neonates in the first 72 hours

2017 ◽  
Vol 54 (1) ◽  
pp. 61-68 ◽  
Author(s):  
Danielle E Forster ◽  
Emmanuel Koumoundouros ◽  
Virginia Saxton ◽  
Gabrielle Fedai ◽  
James Holberton
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Term Neonates ◽  
Cerebrovascular Resistance ◽  
Normal Term ◽  
Blood Flow Velocities ◽  
Flow Velocities

scholarly journals Relationship Between Cerebral Blood Flow Velocities and Cerebral Electrical Activity in Sleep

SLEEP ◽  
1994 ◽  
Vol 17 (1) ◽  
pp. 11-19 ◽  
Author(s):  
Göran Hajak ◽  
Jürgen Klingelhöfer ◽  
Maria Schulz-Varszegi ◽  
Gernot Matzander ◽  
Dirk Sander ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Electrical Activity ◽  
Blood Flow Velocities ◽  
Flow Velocities

scholarly journals Normal values of cerebral blood flow velocities in neonates

2010 ◽  
Vol 138 (3-4) ◽  
pp. 186-191 ◽  
Author(s):  
Brankica Vasiljevic ◽  
Miroslava Gojnic ◽  
Svjetlana Maglajlic-Djukic ◽  
Olga Antonovic
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Normal Values ◽  
Color Doppler ◽  
Ductus Arteriosus ◽  
Resistance Index ◽  
Severe Hypotension ◽  
The Mean ◽  
Blood Flow Velocities ◽  
Flow Velocities

Introduction. There was used color Doppler ultrasonography (cD-USI), allowing simultaneous examination of parenchymal and vascular cerebral structures. The evaluation of blood flow velocities in cerebral arteries is important in the assessment of cerebral circulation in hypoxic-ischaemic and haemorrhagic brain damage in neonates. Objective. The aim of this study was to estimate normal values of cerebral blood flow velocities (CBFV) and Doppler indices - pulsatility index (PI) and resistance index (RI) - in the anterior cerebral artery (ACA) during the first days of life in infants. Methods. CBFV, PI and RI were obtained during the first week of life with cD-US in 70 infants divided in four groups of gestational age (GA): ?28 gestational weeks (GW); 29-32 GW; 33-36 GW; and ?37 GW. Infants with congenital malformations, severe perinatal asphyxia, cerebral haemorrhagic lesion, DAP or severe hypotension were excluded. Results. The mean GA of infants was 34.5?5.5 GW (range 26-40 GW) and the mean birth weight (BW) was 2540?950 g (range 750-4000 g). In the 1st group of 10 infants, ?28 GW, the mean BW was 950?110 g and values of RI were 0.59?0.10 and PI 1.06?0.080. In the 2nd group of 20 infants, 29-32 GW, the mean BW was 1350?290 g and values of RI were 0.60?0.10 and PI 1.10?0.15. In the 3rd group of 20 infants, 33-36 GW, the mean BW was 1950?750 g and values of RI were 0.63?0.08 and PI 1.15?0.30. In the 4th group of 20 infants, ?37 GW, the mean BW was 3540?950 g and values of RI were 0.65?0.05 and PI 1.18?0.35. Conclusion. Values of CBFV progressively increase with GA and BW due to progressive increase of cardiac output, blood pressure and closing of ductus arteriosus. Values of RI and PI gradually increase with GA and BW as a result of progressive maturation and opening of vascular cerebral bed with a reduction of the cerebrovascular resistance.

IN NEUROCYSTICERCOSIS, CSF CYTOKINES CORRELATE WITH CEREBRAL BLOOD FLOW VELOCITIES

Neurology ◽  
2008 ◽  
Vol 71 (14) ◽  
pp. 1119-1122 ◽  
Author(s):  
F. Gongora-Rivera ◽  
J. Luis Soto-Hernandez ◽  
P. Guevara ◽  
J. Sotelo-Morales
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Blood Flow Velocities ◽  
Flow Velocities

Abstract WP567: The Association Between Decreased Cerebral Blood Flow in Transient Ischemic Attack Patients and Cognition

Stroke ◽  
2019 ◽  
Vol 50 (Suppl_1) ◽  
Author(s):  
Meaghan Reid ◽  
Connor McDougall ◽  
Nils Forkert ◽  
Richard Frayne ◽  
Shelagh Coutts ◽  
...  
Keyword(s):  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Transient Ischemic Attack ◽  
Ischemic Attack

scholarly journals Impaired Cerebral Vasomotor Reactivity in Alzheimer’s Disease

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Fernando Gongora-Rivera ◽  
Adolfo Cordero-Perez ◽  
Alejandro Gonzalez-Aquines ◽  
Antonio Anaya-Escamilla ◽  
Eduardo Villarreal-Garza ◽  
...  
Keyword(s):  
Alzheimer’S Disease ◽  
Alzheimer's Disease ◽  
Blood Flow ◽  
Cerebral Blood Flow ◽  
Weak Correlation ◽  
Vasomotor Reactivity ◽  
Cerebral Vasomotor Reactivity ◽  
Reactivity Test ◽  
Blood Flow Velocities ◽  
Flow Velocities

Background. Recent studies have shown that cerebral vascularity may be impaired in Alzheimer’s disease. Cerebral vasomotor reactivity could be an important biomarker for this pathology.Aims. The aim of this study was to investigate the alterations in cerebral vascular motor reactivity in Alzheimer’s disease subjects and to associate these changes with their cognitive scores.Methods. We recruited subjects with a diagnosis of Alzheimer’s disease and healthy controls. Demographic, clinical, imaging, and cognitive test were obtained. Then all participants performed a cerebral vascular motor reactivity test with 7% CO2 and cerebral blood flow velocities (CBFV) were recorded with transcranial doppler ultrasound before and after the test.Results. We recruited 45 subjects, 26 (21 female) Alzheimer’s disease participants and 19 (15 female) healthy controls. There were no differences in baseline cerebral blood flow velocities between the groups. After the cerebral vasomotor reactivity test, absolute mean difference in mean CBFV (ΔCBFV-m) was 8.70±4.14 versus 4.81±6.96 (p<0.01), respectively. Calculated percentage of change (%CVMR) was lower in the AD group 7.45±18.25 versus 23.29±17.48, and there was a positive but weak correlation with mini-mental scores (ρ=0.337, p=0.023).Conclusions. In this study, Alzheimer’s disease subjects showed significant changes in all absolute cerebral blood flow velocities after the cerebral vasomotor reactivity test with CO2, but only diastolic phase responses were statistically significant. There was a positive but weak correlation between cerebral vasomotor reactivity and cognitive scores. Further studies are needed to investigate these effects in larger Latin-American samples.

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