scholarly journals Linking Asymmetric Cell Division to the Terminal Differentiation Program of Postmitotic Neurons in C. elegans

2009 ◽  
Vol 16 (4) ◽  
pp. 563-575 ◽  
Author(s):  
Vincent Bertrand ◽  
Oliver Hobert
Keyword(s):  
Cell Division ◽  
Asymmetric Cell Division ◽  
Terminal Differentiation ◽  
C Elegans ◽  
Postmitotic Neurons

scholarly journals Cortical localization of the G  protein GPA-16 requires RIC-8function during C. elegans asymmetric cell division

Development ◽  
2005 ◽  
Vol 132 (20) ◽  
pp. 4449-4459 ◽  
Author(s):  
K. Afshar ◽  
F. S. Willard ◽  
K. Colombo ◽  
D. P. Siderovski ◽  
P. Gonczy
Keyword(s):  
Cell Division ◽  
G Protein ◽  
Asymmetric Cell Division ◽  
C Elegans ◽  
Cortical Localization

scholarly journals Extracellular control of PAR protein localization during asymmetric cell division in the C. elegans embryo

Development ◽  
2010 ◽  
Vol 137 (19) ◽  
pp. 3337-3345 ◽  
Author(s):  
Y. Arata ◽  
J.-Y. Lee ◽  
B. Goldstein ◽  
H. Sawa
Keyword(s):  
Cell Division ◽  
Asymmetric Cell Division ◽  
Protein Localization ◽  
C Elegans

scholarly journals Regulation of anterior cell-specific mec-3 expression during asymmetric cell division in C. elegans

1992 ◽  
Vol 194 (4) ◽  
pp. 289-302 ◽  
Author(s):  
Jeffrey C. Way ◽  
Jin-Quan Run ◽  
Alice Y. Wang
Keyword(s):  
Cell Division ◽  
Asymmetric Cell Division ◽  
C Elegans

scholarly journals C. elegans Brat homologs regulate PAR protein-dependent polarity and asymmetric cell division

2008 ◽  
Vol 321 (2) ◽  
pp. 368-378 ◽  
Author(s):  
Vincent Hyenne ◽  
Marianne Desrosiers ◽  
Jean-Claude Labbé
Keyword(s):  
Cell Division ◽  
Asymmetric Cell Division ◽  
C Elegans

OOC-3, a novel putative transmembrane protein required for establishment of cortical domains and spindle orientation in the P(1) blastomere of C. elegans embryos

Development ◽  
2000 ◽  
Vol 127 (10) ◽  
pp. 2063-2073 ◽  
Author(s):  
S. Pichler ◽  
P. Gonczy ◽  
H. Schnabel ◽  
A. Pozniakowski ◽  
A. Ashford ◽  
...  
Keyword(s):  
Cell Division ◽  
Asymmetric Cell Division ◽  
Transmembrane Protein ◽  
Cell Stage ◽  
Par Proteins ◽  
Asymmetric Cell Divisions ◽  
C Elegans ◽  
Membrane Compartment ◽  
Chromosome Ii

Asymmetric cell divisions require the establishment of an axis of polarity, which is subsequently communicated to downstream events. During the asymmetric cell division of the P(1) blastomere in C. elegans, establishment of polarity depends on the establishment of anterior and posterior cortical domains, defined by the localization of the PAR proteins, followed by the orientation of the mitotic spindle along the previously established axis of polarity. To identify genes required for these events, we have screened a collection of maternal-effect lethal mutations on chromosome II of C. elegans. We have identified a mutation in one gene, ooc-3, with mis-oriented division axes at the two-cell stage. Here we describe the phenotypic and molecular characterization of ooc-3. ooc-3 is required for the correct localization of PAR-2 and PAR-3 cortical domains after the first cell division. OOC-3 is a novel putative transmembrane protein, which localizes to a reticular membrane compartment, probably the endoplasmic reticulum, that spans the whole cytoplasm and is enriched on the nuclear envelope and cell-cell boundaries. Our results show that ooc-3 is required to form the cortical domains essential for polarity after cell division.

A C. elegans Ror receptor tyrosine kinase regulates cell motility and asymmetric cell division

Nature ◽  
10.1038/23722 ◽  
1999 ◽  
Vol 400 (6747) ◽  
pp. 881-885 ◽  
Author(s):  
Wayne C. Forrester ◽  
Megan Dell ◽  
Elliot Perens ◽  
Gian Garriga
Keyword(s):  
Cell Division ◽  
Tyrosine Kinase ◽  
Cell Motility ◽  
Receptor Tyrosine Kinase ◽  
Asymmetric Cell Division ◽  
C Elegans
Sign in / Sign up

Export Citation Format

Share Document