Risk for cognitive deficit in a population-based sample of U.S. children with autism spectrum disorders: Variation by perinatal health factors

2010 ◽  
Vol 3 (3) ◽  
pp. 202-212 ◽  
Author(s):  
Laura A. Schieve ◽  
Jon Baio ◽  
Catherine E. Rice ◽  
Maureen Durkin ◽  
Russell S. Kirby ◽  
...  
2011 ◽  
Vol 2011 ◽  
pp. 1-8 ◽  
Author(s):  
Claudia Nordenbæk ◽  
Kirsten Ohm Kyvik ◽  
Axel Skytthe ◽  
Niels Bilenberg

This study evaluated the effectiveness of a short scale in screening for autism spectrum disorders (ASDs) and documented the prevalence of ASD in twins born in 1988–2000 as registered in the Danish Psychiatric Central Research Registry (DPCRR). Five child behaviour checklist (CBCL) items were used in a first-phase screening of all twins born 1988–2000, recruited from the Danish Twin Registry. In Denmark, nearly all psychiatric diagnoses are reported to DPCRR, and the two registers were linked for validation purposes. Parents of >16,000 twins responded (68.4%); among the twins, 108 were registered with ASD. The optimal cut-off score of two out of ten yielded a sensitivity of 79.6% and a specificity of 81.4%. The registry linkage identified 176 twins with ASD (point prevalence = 0.72%). This study demonstrates that it is feasible to screen large populations for ASD with a 5-item questionnaire. The prevalence of registered ASD in twins corresponds to recent population-based studies in singletons.


2010 ◽  
Vol 20 (2) ◽  
pp. 42-50 ◽  
Author(s):  
Laura W. Plexico ◽  
Julie E. Cleary ◽  
Ashlynn McAlpine ◽  
Allison M. Plumb

This descriptive study evaluates the speech disfluencies of 8 verbal children between 3 and 5 years of age with autism spectrum disorders (ASD). Speech samples were collected for each child during standardized interactions. Percentage and types of disfluencies observed during speech samples are discussed. Although they did not have a clinical diagnosis of stuttering, all of the young children with ASD in this study produced disfluencies. In addition to stuttering-like disfluencies and other typical disfluencies, the children with ASD also produced atypical disfluencies, which usually are not observed in children with typically developing speech or developmental stuttering. (Yairi & Ambrose, 2005).


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