Life saving cyclophosphamide treatment in a girl with giant cell hepatitis and autoimmune haemolytic anaemia: Case report and up-to-date on therapeutical options

2006 ◽  
Vol 38 (11) ◽  
pp. 846-850 ◽  
Author(s):  
P. Vajro ◽  
F. Migliaro ◽  
C. Ruggeri ◽  
N. Di Cosmo ◽  
G. Crispino ◽  
...  
1997 ◽  
Vol 77 (3) ◽  
pp. 249-251 ◽  
Author(s):  
H. V. Melendez ◽  
M. Rela ◽  
A. J Baker ◽  
C. Ball ◽  
B. Portmann ◽  
...  

2014 ◽  
Vol 25 (1) ◽  
Author(s):  
Hasan M. Isa ◽  
◽  
Lina F. Al Ali ◽  
Afaf M. Mohamed ◽  
Rawia M. Hamad ◽  
...  

2003 ◽  
Vol 24 (1) ◽  
pp. 34-36 ◽  
Author(s):  
N. Tuncer Elmaci ◽  
S. Ratip ◽  
D. ?nce-G�nal ◽  
T. Tanrida?

2018 ◽  
Vol 2018 ◽  
pp. 1-5 ◽  
Author(s):  
Pinelopi Arvaniti ◽  
Kalliopi Zachou ◽  
George K. Koukoulis ◽  
George N. Dalekos

Giant cell hepatitis (GCH) is commonly reported in neonatal and infantile liver diseases but rarely in adults where the term postinfantile GCH (PIGCH) is used. PIGCH is associated with many diseases, including drugs toxicity, viruses, and autoimmune liver diseases, with autoimmune hepatitis (AIH) being the most prevalent. We present a case of PIGCH in a 76-year-old female without known history of liver disease who suffered from an acute severe episode of hepatitis. After careful exclusion of other hepatitis causes by imaging, virological, immunological, and microbiological investigations, a diagnosis of acute severe AIH (AS-AIH) was established. The patient was started on corticosteroids but she did not respond and died 3 days later because of advanced acute liver failure. Postmortem liver biopsy showed typical PIGCH lesions. Physicians must keep this catastrophic entity in mind in cases of unexplained acute liver injury as, contrary to our case, prompt rescue therapy with corticosteroids may be life-saving.


2009 ◽  
Vol 41 ◽  
pp. S226-S227
Author(s):  
M.P. Cicalese ◽  
R. Iorio ◽  
J. Rweyemamu ◽  
N. Hadzic ◽  
M. Samyn ◽  
...  

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