Association between physical activity and inflammatory bowel disease risk: A meta-analysis

2016 ◽  
Vol 48 (12) ◽  
pp. 1425-1431 ◽  
Author(s):  
Qiang Wang ◽  
Ke-Qun Xu ◽  
Xiang-Rong Qin ◽  
Wen-Lu ◽  
Yan-Liu ◽  
...  
Keyword(s):  
Physical Activity ◽  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Disease Risk ◽  
Meta Analysis ◽  
Inflammatory Bowel

Association between NCF4 rs4821544T/C polymorphism and inflammatory bowel disease risk in Caucasian: a meta-analysis

2015 ◽  
Vol 64 (10) ◽  
pp. 825-831 ◽  
Author(s):  
Peng-Bo Wu ◽  
Jin-Fen Dai ◽  
Qian Wang ◽  
Guo Zhang ◽  
Shi-Yun Tan ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Disease Risk ◽  
Meta Analysis ◽  
Inflammatory Bowel

scholarly journals The -173 G/C Polymorphism of the MIF Gene and Inflammatory Bowel Disease Risk: A Meta-Analysis

2013 ◽  
Vol 14 (6) ◽  
pp. 11392-11401 ◽  
Author(s):  
Yongchun Shen ◽  
Shujin Guo ◽  
Ting Yang ◽  
Liuqun Jia ◽  
Lei Chen ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Disease Risk ◽  
Meta Analysis ◽  
Inflammatory Bowel

MDR1 C3435T polymorphism and inflammatory bowel disease risk: a meta-analysis

2014 ◽  
Vol 41 (4) ◽  
pp. 2679-2685 ◽  
Author(s):  
Jun Wang ◽  
Xufeng Guo ◽  
Shijie Yu ◽  
Jixiang Zhang ◽  
Jia Song ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Disease Risk ◽  
Meta Analysis ◽  
C3435t Polymorphism ◽  
Inflammatory Bowel

The -A2518G polymorphism in theMCP-1gene and inflammatory bowel disease risk: A meta-analysis

2015 ◽  
Vol 16 (4) ◽  
pp. 177-185 ◽  
Author(s):  
Yu Wen Li ◽  
Ci Qiu Yang ◽  
Ying Lian Xiao ◽  
Jie Li ◽  
Chen Xi Xie ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Disease Risk ◽  
Meta Analysis ◽  
Inflammatory Bowel

scholarly journals C3435T Polymorphism of the ABCB1 Gene in Polish Patients with Inflammatory Bowel Disease: A Case–Control and Meta-Analysis Study

Genes ◽  
2021 ◽  
Vol 12 (9) ◽  
pp. 1419
Author(s):  
Paweł Petryszyn ◽  
Robert Dudkowiak ◽  
Agnieszka Gruca ◽  
Ewa Jaźwińska-Tarnawska ◽  
Paweł Ekk-Cierniakowski ◽  
...  
Keyword(s):  
Inflammatory Bowel Disease ◽  
Bowel Disease ◽  
Disease Risk ◽  
Meta Analysis ◽  
Specific Treatment ◽  
Colonic Disease ◽  
Abcb1 Gene ◽  
C3435t Polymorphism ◽  
Significant Difference ◽  
Inflammatory Bowel

P-glycoprotein encoded by the ABCB1 gene constitutes a molecular barrier in the small and large bowel epithelium, and its different expression may influence susceptibility to inflammatory bowel disease (IBD). We aimed to assess the contribution of the C3435T polymorphism to disease risk in the Polish population. A total of 100 patients (50 Crohn’s disease (CD), 50 ulcerative colitis (UC)) and 100 healthy controls were genotyped for the single nucleotide polymorphism (SNP) C3435T by using the PCR-RFLP method. Patients were classified on the basis of disease phenotype and the specific treatment used. A meta-analysis was carried out of our results and those from previously published Polish studies. There was no significant difference in allele and genotype frequencies in IBD patients compared with controls. For CD patients, a lower frequency of TT genotype in those with colonic disease, a lower frequency of T allele, and a higher frequency of C allele in those with luminal disease were observed, whereas for UC patients, a lower frequency of CT genotype was observed in those with left-sided colitis. A meta-analysis showed a tendency towards higher prevalence of CC genotype in UC cases. These results indicate that the C3435T variants may confer a risk for UC and influence disease behaviour.

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