Diagnostic ability of blue laser imaging combined with magnifying endoscopy for early esophageal cancer

Abstract Background and study aims The Japan Narrow-band imaging (NBI) Expert Team (JNET) classification was proposed for evaluating colorectal lesions. However, it remains unknown whether the JNET classification can be applied to magnifying endoscopy with image-enhanced endoscopies other than NBI. This study aimed to compare the diagnostic ability of JNET classification by magnifying endoscopy with blue laser imaging (ME-BLI) and with ME-NBI. Patients and methods We retrospectively assessed consecutive patients diagnosed per the JNET classification by ME-BLI (BLI group) or ME-NBI (NBI group) between March 2014 and June 2017. We compared the diagnostic value of JNET classification between the groups with one-to-one propensity score matching. Results Four hundred and seventy-one propensity score-matched pairs of lesions were analyzed. In the BLI and NBI groups, the overall diagnostic accuracies were 92.1 % and 91.7 %, respectively, and those for differentiating between neoplastic and non-neoplastic polyps were 96.6 % and 96.8 %, respectively. The positive predictive value by each JNET classification in BLI vs. NBI group was 90.6 % vs. 96.2 % in Type 1, 94.3 % vs. 94.6 % in Type 2A, 57.7 % vs. 42.3 % in Type 2B, and 100 % vs. 91.7 % in Type 3. The negative predictive value was 97.0 % vs. 96.9 % in Type 1, 88.1 % vs. 82.8 % in Type 2A, 98.0 % vs. 98.2 % in Type 2B, and 98.5 % vs. 98.7 % in Type 3. No statistical difference in the diagnostic results was found between the groups. Conclusions The diagnostic ability of the JNET classification by ME-BLI and ME-NBI was comparable, with the former also applicable for diagnosis of colorectal lesions.

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Diagnosis of early esophageal cancer using blue laser imaging (BLI)

Digestive and Liver Disease ◽

10.1016/j.dld.2018.08.011 ◽

2018 ◽

Vol 50 (10) ◽

pp. 977-978 ◽

Cited By ~ 1

Author(s):

Helmut Neumann ◽

Cesare Hassan

Keyword(s):

Esophageal Cancer ◽

Blue Laser ◽

Early Esophageal Cancer ◽

Laser Imaging ◽

Blue Laser Imaging

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Mo1527 A Computer-Based System for Quantitative Diagnosis of Early Gastric Cancer Under Blue LASER Imaging-Magnifying Endoscopy

Gastrointestinal Endoscopy ◽

10.1016/j.gie.2014.02.704 ◽

2014 ◽

Vol 79 (5) ◽

pp. AB471

Author(s):

Shigeto Yoshida ◽

Rie Miyaki ◽

Yoko Kominami ◽

Yoji Sanomura ◽

Taiji Matsuo ◽

...

Keyword(s):

Gastric Cancer ◽

Early Gastric Cancer ◽

Magnifying Endoscopy ◽

Blue Laser ◽

Laser Imaging ◽

Quantitative Diagnosis ◽

Blue Laser Imaging ◽

Computer Based

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Sa1668 Usefulness of Magnifying Endoscopy With Blue LASER Imaging for Diagnosis of Early Gastric Cancer

Gastrointestinal Endoscopy ◽

10.1016/j.gie.2013.03.719 ◽

2013 ◽

Vol 77 (5) ◽

pp. AB285 ◽

Cited By ~ 1

Author(s):

Rie Miyaki ◽

Shigeto Yoshida ◽

Shinji Tanaka ◽

Yoko Kominami ◽

Yoji Sanomura ◽

...

Keyword(s):

Gastric Cancer ◽

Early Gastric Cancer ◽

Magnifying Endoscopy ◽

Blue Laser ◽

Laser Imaging ◽

Blue Laser Imaging

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Magnifying Endoscopy with Blue Laser Imaging Improves the Microstructure Visualization in Early Gastric Cancer: Comparison of Magnifying Endoscopy with Narrow-Band Imaging

Gastroenterology Research and Practice ◽

10.1155/2017/8303046 ◽

2017 ◽

Vol 2017 ◽

pp. 1-7 ◽

Cited By ~ 9

Author(s):

Reiko Kimura-Tsuchiya ◽

Osamu Dohi ◽

Yasuko Fujita ◽

Nobuaki Yagi ◽

Atsushi Majima ◽

...

Keyword(s):

Gastric Cancer ◽

Narrow Band ◽

Narrow Band Imaging ◽

Magnifying Endoscopy ◽

Blue Laser ◽

Pathological Features ◽

Laser Imaging ◽

Group A ◽

Blue Laser Imaging ◽

Group B

Backgrounds. Magnifying endoscopy with blue laser imaging (ME-BLI) for diagnosis of early gastric cancer (EGC) is as effective as magnifying endoscopy with narrow-band imaging (ME-NBI). However, there are different EGCs in microstructure visualization between ME-BLI and ME-NBI. This study aimed to clarify the pathological features of the EGCs, in which microstructure visualization was different between ME-NBI and ME-BLI. Methods. EGCs were classified into groups A (irregular microsurface pattern (MSP) in ME-BLI and absent MSP in ME-NBI), B (irregular MSP in two modalities), or C (absent MSP in two modalities), according to the vessel plus surface classification. We compared the pathological features of EGCs between the three groups. Results. 17, four, and five lesions could be evaluated in detail in groups A, B and C, respectively. Well-differentiated adenocarcinomas with shallow crypts were more frequent in group A than in group B (58.8 and 0%, resp.). The mean crypt depth of group A was significantly shallower than that of group B (56 ± 20, 265 ± 64 μm, resp., P=0.0002). Conclusions. ME-BLI could better visualize the microstructures of the EGCs with shallow crypts compared with ME-NBI. Therefore, ME-BLI could enable a more accurate diagnosis of EGC with shallow crypts.

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Magnifying Endoscopy: Image-Enhanced Endoscopy Focused on JNET Classification—Blue Laser Imaging (BLI)

Endoscopic Management of Colorectal T1(SM) Carcinoma ◽

10.1007/978-981-13-6649-9_4 ◽

2020 ◽

pp. 25-33

Author(s):

Naohisa Yoshida ◽

Ken Inoue ◽

Ryohei Hirose

Keyword(s):

Magnifying Endoscopy ◽

Blue Laser ◽

Laser Imaging ◽

Blue Laser Imaging

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Diagnostic value of blue laser imaging combined with magnifying endoscopy for precancerous and early gastric cancer lesions

The Turkish Journal of Gastroenterology ◽

10.5152/tjg.2019.18210 ◽

2019 ◽

Vol 30 (6) ◽

pp. 549-556 ◽

Cited By ~ 2

Author(s):

Yang Zhenming ◽

◽

Shen Lei ◽

Keyword(s):

Gastric Cancer ◽

Early Gastric Cancer ◽

Diagnostic Value ◽

Magnifying Endoscopy ◽

Blue Laser ◽

Laser Imaging ◽

Blue Laser Imaging

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Clinical Usefulness of the VS Classification System Using Magnifying Endoscopy with Blue Laser Imaging for Early Gastric Cancer

Gastroenterology Research and Practice ◽

10.1155/2017/3649705 ◽

2017 ◽

Vol 2017 ◽

pp. 1-6 ◽

Cited By ~ 6

Author(s):

Yoshikazu Yoshifuku ◽

Yoji Sanomura ◽

Shiro Oka ◽

Kazutaka Kuroki ◽

Mio Kurihara ◽

...

Keyword(s):

Gastric Cancer ◽

Early Gastric Cancer ◽

Classification System ◽

Magnifying Endoscopy ◽

Blue Laser ◽

Laser Imaging ◽

Blue Laser Imaging ◽

Vs Classification ◽

H Pylori ◽

Experienced Endoscopists

Background. Blue laser imaging (BLI) enables the acquisition of more information from tumors’ surfaces compared with white light imaging. Few reports confirm the validity of magnifying endoscopy (ME) with BLI (ME-BLI) for early gastric cancer (EGC). We aimed to assess the detailed endoscopic findings from EGCs using ME-BLI. Methods. We enrolled 386 consecutive patients with 417 EGCs that were diagnosed using ME-BLI and resected by endoscopic submucosal dissection. Using the VS classification system, three highly experienced endoscopists (HEEs) and three less experienced endoscopists (LEEs) evaluated the demarcation line (DL), microsurface pattern (MSP), and microvascular pattern (MVP) within the endoscopic images of EGCs obtained using ME-BLI, assigning high-confidence (HC) or low-confidence (LC) levels. We investigated the clinicopathological features associated with each confidence level. Results. The HEEs’ evaluations determined the presence of DL in 99%, irregular MSP in 96%, and irregular MVP in 96%, and the LEEs’ evaluations determined the presence of DL in 98%, irregular MSP in 95%, and irregular MVP in 95% of the EGCs. When DL was present, HC levels in the Helicobacter pylori- (H. pylori-) eradicated group and noneradicated group were evident in 65% and 89%, a difference that was significant (p<0.001). Conclusions. In the diagnosis of EGC with ME-BLI, the VS classification system with ME-NBI can be applied, but identifying the DL after H. pylori was difficult.

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