Ethnic sensitivity assessment of pharmacokinetics and pharmacodynamics of omalizumab with dosing table expansion

2016 ◽  
Vol 31 (3) ◽  
pp. 173-184 ◽  
Author(s):  
Wataru Honma ◽  
Aurélie Gautier ◽  
Ines Paule ◽  
Masayuki Yamaguchi ◽  
Philip J. Lowe
Keyword(s):  
Pharmacokinetics And Pharmacodynamics ◽  
Sensitivity Assessment ◽  
Ethnic Sensitivity

Pharmacokinetics and pharmacodynamics of meperidine in healthy horses

2020 ◽  
Vol 47 (6) ◽  
pp. 855.e11-855.e12
Author(s):  
H. Trenholme ◽  
A. Hanafi ◽  
R. Reed ◽  
D. Sakai ◽  
C. Ryan ◽  
...  
Keyword(s):  
Pharmacokinetics And Pharmacodynamics

pharmacokinetics and pharmacodynamics of a 4-week up-titration regimen of roflumilast in the optimize study

Pneumologie ◽  
2018 ◽  
Vol 72 (S 01) ◽  
pp. S92-S92
Author(s):  
A Facius ◽  
N Bagul ◽  
P gardiner ◽  
H Watz
Keyword(s):  
Pharmacokinetics And Pharmacodynamics

Preparation of scutellarin loaded TPGS polymeric micelles and evaluation of its pharmacokinetics and pharmacodynamics effects in rats

2018 ◽  
Vol 75 (6) ◽  
pp. 1305-1312
Author(s):  
Liu Zou ◽  
Shujuan Xiong ◽  
Xiangping Deng ◽  
Juan Liu ◽  
Runde Xiong ◽  
...  
Keyword(s):  
Polymeric Micelles ◽  
Pharmacokinetics And Pharmacodynamics

Baroreflex Sensitivity Assessment – Latest Advances and Strategies

2011 ◽  
Vol 7 (2) ◽  
pp. 89 ◽  
Author(s):  
Maria Teresa La Rovere ◽  
Roberto Maestri ◽  
Gian Domenico Pinna ◽  
◽  
◽  
...  
Keyword(s):  
Baroreflex Sensitivity ◽  
Carotid Sinus ◽  
Lower Blood Pressure ◽  
Vasomotor Tone ◽  
Sensitivity Assessment ◽  
Lower Blood ◽  
Prognostic Implications ◽  
Novel Therapeutic Strategies ◽  
Sympathetic Vasomotor Tone ◽  
Stimulation Of

The baroreflex mechanism has been recognised as a key part of cardiovascular regulation. Alterations in the baroreceptor-heart rate reflex (baroreflex sensitivity [BRS]) contribute to sympathetic–parasympathetic imbalance, playing a major role in the development and progression of many cardiovascular disorders. Therefore, the measurement of the baroreflex is a source of valuable information in the clinical management of cardiac disease patients. This article reviews the most relevant advances for the measurement of BRS and their clinical and prognostic implications. Novel therapeutic strategies, exploring the use of electrical stimulation of the carotid sinus, have been evaluated recently in experimental and preliminary clinical studies to lower blood pressure and to reduce the level of baroreflex-mediated sympathoexcitation in heart failure. A recent study has also shown that the implementation of an artificial baroreflex system to regulate sympathetic vasomotor tone automatically is feasible.

Impact of Endogenous Insulin Adjustment Methods on the Assessment of Insulin Pharmacokinetics and Pharmacodynamics

Diabetes ◽  
2018 ◽  
Vol 67 (Supplement 1) ◽  
pp. 1051-P
Author(s):  
SANG M. CHUNG ◽  
JUSTIN A. PENZENSTADLER ◽  
MANOJ KHURANA ◽  
CHANDRAHAS SAHAJWALLA
Keyword(s):  
Pharmacokinetics And Pharmacodynamics ◽  
Insulin Pharmacokinetics ◽  
Endogenous Insulin
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