MC1R variant alleles and malignant melanoma risk in Israel

2009 ◽  
Vol 45 (11) ◽  
pp. 2015-2022 ◽  
Author(s):  
Gilli Galore-Haskel ◽  
Esther Azizi ◽  
Hamida Mohamdi ◽  
Alon Scope ◽  
Valérie Chaudru ◽  
...  

2008 ◽  
Vol 19 (7) ◽  
pp. 759-765 ◽  
Author(s):  
Charlotte Gerd Hannibal ◽  
Allan Jensen ◽  
Heidi Sharif ◽  
Susanne Krüger Kjaer


2020 ◽  
Vol 63 (3) ◽  
pp. 101-112
Author(s):  
Fatemeh Asadian ◽  
Seyed Mohammadreza Niktabar ◽  
Yaser Ghelmani ◽  
Shadi Kargar ◽  
Elahe Akbarian ◽  
...  

Background: A number of studies have reported that the xeroderma pigmentosum complementation group C (XPC) polymorphisms are associated with cutaneous malignant melanoma (CMM) susceptibility. But the results of those studies were inconsistent. Here, we performed a study to obtain a more conclusive result on the association of XPC polymorphisms with risk of CMM. Methods: The XPC Lys939Gln and Ala499Val polymorphisms were genotyped in 150 CMM cases and 150 controls by PCR-RFLP assay. Subsequently, all published relevant studies were identified through a comprehensive literature search in PubMed, Web of Science, and CNKI databases. Odds ratios (ORs) and 95% confidence intervals (CIs) were calculated to estimate the strength of correlation. Results: There was no significant association between XPC Lys939Gln and Ala499Val polymorphisms and CMM risk in our population. A total of 15 case-control studies including ten studies with 5,990 cases and 7,697 controls on XPC Lys939Gln and five studies with 3,139 cases and 3,721 controls on XPC Ala499Val polymorphism were selected. Pooled data revealed that XPC Lys939Gln (C vs. A: OR = 1.108, 95% CI 1.008– 1.217; P = 0.033) and Ala499Val (C vs. A: OR = 0.918, 95% CI 0.850–0.992; p = 0.031; CC+CA vs. AA: OR = 0.904, 95% CI 0.819–0.997; p = 0.043) polymorphisms were significantly associated with an increased risk of CMM. Moreover, stratified analyses by ethnicity revealed that the XPC Ala499Val and Lys939Gln polymorphisms were significantly associated with risk of CMM in Caucasians and mixed populations, respectively. Conclusions: This meta-analysis result suggested that XPC Lys939Gln and Ala499Val polymorphisms were significantly associated with risk of CMM.



2017 ◽  
pp. 1-6
Author(s):  
Ezgi Ağadayı ◽  
Aybüke Demir Alsancak ◽  
Duygu Üstünol ◽  
İrfan Şencan ◽  
Hatice Küçükceran ◽  
...  


2003 ◽  
Vol 93 (1) ◽  
pp. 11-b-12 ◽  
Author(s):  
Stephen W. Marshall ◽  
Charles Poole ◽  
Anna E. Waller




2007 ◽  
Vol 16 (18) ◽  
pp. 2249-2260 ◽  
Author(s):  
K. A. Beaumont ◽  
S. L. Shekar ◽  
R. A. Newton ◽  
M. R. James ◽  
J. L. Stow ◽  
...  


1992 ◽  
Vol 28 (1) ◽  
pp. 89-94 ◽  
Author(s):  
Craig L. Slingluff ◽  
Hilliard F. Seigler


PLoS ONE ◽  
2016 ◽  
Vol 11 (1) ◽  
pp. e0147056 ◽  
Author(s):  
Jibin Liu ◽  
Biao Shen ◽  
Minxin Shi ◽  
Jing Cai


1991 ◽  
Vol 2 (6) ◽  
pp. 401-411 ◽  
Author(s):  
Thomas M. Mack ◽  
Birgitta Floderus


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