Azetidine derivatives as novel γ-aminobutyric acid uptake inhibitors: Synthesis, biological evaluation, and structure–activity relationship

Mark R. Faust; Georg Höfner; Jörg Pabel; Klaus T. Wanner

doi:10.1016/j.ejmech.2010.02.029

Azetidine derivatives as novel γ-aminobutyric acid uptake inhibitors: Synthesis, biological evaluation, and structure–activity relationship

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2010.02.029 ◽

2010 ◽

Vol 45 (6) ◽

pp. 2453-2466 ◽

Cited By ~ 25

Author(s):

Mark R. Faust ◽

Georg Höfner ◽

Jörg Pabel ◽

Klaus T. Wanner

Keyword(s):

Structure Activity Relationship ◽

Biological Evaluation ◽

Aminobutyric Acid ◽

Activity Relationship ◽

Acid Uptake ◽

Structure Activity ◽

Uptake Inhibitors

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ChemInform Abstract: Azetidine Derivatives as Novel γ-Aminobutyric Acid Uptake Inhibitors: Synthesis, Biological Evaluation, and Structure-Activity Relationship.

ChemInform ◽

10.1002/chin.201039222 ◽

2010 ◽

Vol 41 (39) ◽

pp. no-no

Author(s):

Mark R. Faust ◽

Georg Hoefner ◽

Joerg Pabel ◽

Klaus T. Wanner

Keyword(s):

Structure Activity Relationship ◽

Biological Evaluation ◽

Aminobutyric Acid ◽

Activity Relationship ◽

Acid Uptake ◽

Structure Activity ◽

Uptake Inhibitors

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Synthesis, biological evaluation and structure–activity relationship of new GABA uptake inhibitors, derivatives of 4-aminobutanamides

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2014.06.024 ◽

2014 ◽

Vol 83 ◽

pp. 256-273 ◽

Cited By ~ 11

Author(s):

Paula Kowalczyk ◽

Kinga Sałat ◽

Georg C. Höfner ◽

Marta Mucha ◽

Anna Rapacz ◽

...

Keyword(s):

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Gaba Uptake ◽

Structure Activity ◽

Uptake Inhibitors ◽

Relationship Of ◽

Derivatives Of ◽

Gaba Uptake Inhibitors

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Structure Activity Relationship of Arylidene Pyrrolo and Pyrido [2,1-b] Quinazolones as Cytotoxic Agents: Synthesis, SAR Studies, Biological Evaluation and Docking Studies

Medicinal Chemistry ◽

10.2174/1573406411309050003 ◽

2013 ◽

Vol 9 (5) ◽

pp. 642-650 ◽

Cited By ~ 3

Author(s):

Veenu Mangla ◽

Kunal Nepali ◽

Gagandip Singh ◽

Jagjeet Singh ◽

Santosh Guru ◽

...

Keyword(s):

Structure Activity Relationship ◽

Docking Studies ◽

Biological Evaluation ◽

Cytotoxic Agents ◽

Activity Relationship ◽

Sar Studies ◽

Structure Activity ◽

Relationship Of

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Design, synthesis, biological evaluation and structure-activity relationship study of quinazolin-4(3H)-one derivatives as novel USP7 inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113291 ◽

2021 ◽

pp. 113291

Author(s):

Peng Li ◽

Ying Liu ◽

Hua Yang ◽

Hong-Min Liu

Keyword(s):

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Relationship Study

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Structure–Activity Relationship Study and Biological Evaluation of 2-(Disubstituted phenyl)-indole-5-propanoic Acid Derivatives as GPR40 Full Agonists

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.1c00031 ◽

2021 ◽

Vol 64 (7) ◽

pp. 4130-4149

Author(s):

Xiaodi Zhao ◽

Dong-Oh Yoon ◽

Jaeho Yoo ◽

Hyun-Ju Park

Keyword(s):

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Propanoic Acid ◽

Structure Activity ◽

Relationship Study

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Melanin-concentrating hormone receptor 1 antagonists: Synthesis, structure–activity relationship, docking studies, and biological evaluation of 2,3,4,5-tetrahydro-1H-3-benzazepine derivatives

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2011.09.007 ◽

2011 ◽

Vol 19 (21) ◽

pp. 6261-6273 ◽

Cited By ~ 10

Author(s):

Shizuo Kasai ◽

Masahiro Kamaura ◽

Makoto Kamata ◽

Kazuyoshi Aso ◽

Hitomi Ogino ◽

...

Keyword(s):

Hormone Receptor ◽

Structure Activity Relationship ◽

Docking Studies ◽

Biological Evaluation ◽

Activity Relationship ◽

Structure Activity ◽

Melanin Concentrating Hormone

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Structure–activity relationship study at the 3′-N-position of paclitaxel: synthesis and biological evaluation of 3′-N-acyl-paclitaxel analogues

Bioorganic & Medicinal Chemistry ◽

10.1016/s0968-0896(02)00218-3 ◽

2002 ◽

Vol 10 (10) ◽

pp. 3145-3151 ◽

Cited By ~ 17

Author(s):

E Roh

Keyword(s):

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Structure Activity ◽

Relationship Study ◽

Synthesis And Biological Evaluation

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Biological Evaluation, Structure−Activity Relationships, and Three-Dimensional Quantitative Structure−Activity Relationship Studies of Dihydro-β-agarofuran Sesquiterpenes as Modulators of P-Glycoprotein-Dependent Multidrug Resistance

Journal of Medicinal Chemistry ◽

10.1021/jm070290v ◽

2007 ◽

Vol 50 (20) ◽

pp. 4808-4817 ◽

Cited By ~ 30

Author(s):

Carolina P. Reyes ◽

Francisco Muñoz-Martínez ◽

Ivan R. Torrecillas ◽

Cristina R. Mendoza ◽

Francisco Gamarro ◽

...

Keyword(s):

Multidrug Resistance ◽

Three Dimensional ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Quantitative Structure ◽

Structure Activity Relationships ◽

Structure Activity ◽

P Glycoprotein

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Potent and orally bioavailable CDK8 inhibitors: Design, synthesis, structure-activity relationship analysis and biological evaluation

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113248 ◽

2021 ◽

Vol 214 ◽

pp. 113248

Author(s):

Mingfeng Yu ◽

Theodosia Teo ◽

Yuchao Yang ◽

Manjun Li ◽

Yi Long ◽

...

Keyword(s):

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Design Synthesis ◽

Relationship Analysis ◽

Structure Activity ◽

Orally Bioavailable

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ChemInform Abstract: Synthesis, Quantitative Structure-Activity Relationship and Biological Evaluation of 1,3,4-Oxadiazole Derivatives Possessing Diphenylamine Moiety as Potential Anticancer Agents.

ChemInform ◽

10.1002/chin.201329144 ◽

2013 ◽

Vol 44 (29) ◽

pp. no-no

Author(s):

Doaa Ezzat Abdel Rahman

Keyword(s):

Anticancer Agents ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Quantitative Structure ◽

Structure Activity ◽

Oxadiazole Derivatives

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