Benzo[ d ]thiazol-2-yl(piperazin-1-yl)methanones as new anti-mycobacterial chemotypes: Design, synthesis, biological evaluation and 3D-QSAR studies

2016 ◽  
Vol 116 ◽  
pp. 187-199 ◽  
Author(s):  
Sahaj Pancholia ◽  
Tejas M. Dhameliya ◽  
Parth Shah ◽  
Pradeep S. Jadhavar ◽  
Jonnalagadda Padma Sridevi ◽  
...  
Keyword(s):  
3D Qsar ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Qsar Studies

scholarly journals Design, synthesis, and biological evaluation of new 6,N2-diaryl-1,3,5-triazine-2,4-diamines as anticancer agents selectively targeting triple negative breast cancer cells

RSC Advances ◽  
2020 ◽  
Vol 10 (43) ◽  
pp. 25517-25528
Author(s):  
Ahmad Junaid ◽  
Felicia Phei Lin Lim ◽  
Edward R. T. Tiekink ◽  
Anton V. Dolzhenko
Keyword(s):  
Breast Cancer ◽  
Triple Negative Breast Cancer ◽  
Anticancer Agents ◽  
Breast Cancer Cells ◽  
Triple Negative ◽  
3D Qsar ◽  
Qsar Model ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Synthesis And Biological Evaluation

New highly potent and selective 6,N2-diaryl-1,3,5-triazine-2,4-diamines were designed and prepared using the 3D-QSAR model developed earlier.

Design, synthesis, biological evaluation, and 3D-QSAR analysis of podophyllotoxin-dioxazole combination as tubulin targeting anticancer agents

2017 ◽  
Vol 90 (2) ◽  
pp. 236-243 ◽  
Author(s):  
Zi-Zhen Wang ◽  
Wen-Xue Sun ◽  
Xue Wang ◽  
Ya-Han Zhang ◽  
Han-Yue Qiu ◽  
...  
Keyword(s):  
Anticancer Agents ◽  
3D Qsar ◽  
Biological Evaluation ◽  
Design Synthesis ◽  
Qsar Analysis

Synthesis, biological evaluation and 3D-QSAR studies of new chalcone derivatives as inhibitors of human P-glycoprotein

2014 ◽  
Vol 22 (7) ◽  
pp. 2311-2319 ◽  
Author(s):  
Zahida Parveen ◽  
Gerda Brunhofer ◽  
Ishrat Jabeen ◽  
Thomas Erker ◽  
Peter Chiba ◽  
...  
Keyword(s):  
3D Qsar ◽  
Biological Evaluation ◽  
Qsar Studies ◽  
Chalcone Derivatives ◽  
P Glycoprotein

Synthesis, biological evaluation, 3D-QSAR studies of novel aryl-2H-pyrazole derivatives as telomerase inhibitors

2013 ◽  
Vol 23 (4) ◽  
pp. 1091-1095 ◽  
Author(s):  
Yin Luo ◽  
Shuai Zhang ◽  
Ke-Ming Qiu ◽  
Zhi-Jun Liu ◽  
Yu-Shun Yang ◽  
...  
Keyword(s):  
3D Qsar ◽  
Biological Evaluation ◽  
Pyrazole Derivatives ◽  
Qsar Studies ◽  
Telomerase Inhibitors

scholarly journals Synthesis, biological evaluation and 3D-QSAR studies of 3-keto salicylic acid chalcones and related amides as novel HIV-1 integrase inhibitors

2011 ◽  
Vol 19 (6) ◽  
pp. 2030-2045 ◽  
Author(s):  
Horrick Sharma ◽  
Shivaputra Patil ◽  
Tino W. Sanchez ◽  
Nouri Neamati ◽  
Raymond F. Schinazi ◽  
...  
Keyword(s):  
Salicylic Acid ◽  
3D Qsar ◽  
Biological Evaluation ◽  
Integrase Inhibitors ◽  
Qsar Studies ◽  
Hiv 1

3-Heterocycle-PhenylN-Alkylcarbamates as FAAH Inhibitors: Design, Synthesis and 3D-QSAR Studies

ChemMedChem ◽  
2010 ◽  
Vol 5 (2) ◽  
pp. 213-231 ◽  
Author(s):  
Heikki Käsnänen ◽  
Mikko J. Myllymäki ◽  
Anna Minkkilä ◽  
Antti O. Kataja ◽  
Susanna M. Saario ◽  
...  
Keyword(s):  
3D Qsar ◽  
Design Synthesis ◽  
Qsar Studies ◽  
Faah Inhibitors

Novel pyrrolidine-2,4-dione derivatives containing pharmacophores of both hydrazine and diphenyl ether as potential antifungal agents: design, synthesis, biological evaluation, and 3D-QSAR study

2020 ◽  
Vol 44 (46) ◽  
pp. 20071-20082
Author(s):  
Hao-Ran Hu ◽  
An Wang ◽  
Ling-Ling Qiu ◽  
Xiao-Bin Wang ◽  
Min Chen ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Scanning Electron Microscopy ◽  
Antifungal Activity ◽  
Antifungal Agents ◽  
Diphenyl Ether ◽  
3D Qsar ◽  
Biological Evaluation ◽  
Qsar Study ◽  
Design Synthesis ◽  
Scanning Electron

Novel pyrrolidine-2,4-dione derivatives were designed based on natural products. Some synthesized compounds showed excellent antifungal activity. Scanning electron microscopy was used to observe mycelium morphology. 3D-QSAR was also studied.

scholarly journals Modification, Biological Evaluation and 3D QSAR Studies of Novel 2-(1,3-Diaryl- 4,5-Dihydro-1H-Pyrazol-5-yl)Phenol Derivatives as Inhibitors of B-Raf Kinase

PLoS ONE ◽  
2014 ◽  
Vol 9 (5) ◽  
pp. e95702 ◽  
Author(s):  
Yu-Shun Yang ◽  
Fei Zhang ◽  
Dan-Jie Tang ◽  
Yong-Hua Yang ◽  
Hai-Liang Zhu
Keyword(s):  
3D Qsar ◽  
Biological Evaluation ◽  
Qsar Studies ◽  
Raf Kinase ◽  
Phenol Derivatives
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