Design, synthesis and biological evaluation of 2-hydrazinyladenosine derivatives as A2A adenosine receptor ligands

ChemInform Abstract: Design, Synthesis, and Biological Evaluation of a Second Generation of Pyrazolo[4,3-e]-1,2,4-triazolo[1,5-c]pyrimidines as Potent and Selective A2A Adenosine Receptor Antagonists.

ChemInform ◽

10.1002/chin.199839176 ◽

2010 ◽

Vol 29 (39) ◽

pp. no-no

Author(s):

P. G. BARALDI ◽

B. CACCIARI ◽

G. SPALLUTO ◽

M. BERGONZONI ◽

S. DIONISOTTI ◽

...

Keyword(s):

Adenosine Receptor ◽

Second Generation ◽

Biological Evaluation ◽

Receptor Antagonists ◽

A2a Adenosine Receptor ◽

Design Synthesis ◽

Design, Synthesis, and Biological Evaluation of Novel 2-((2-(4-(Substituted)phenylpiperazin-1-yl)ethyl)amino)-5′-N-ethylcarboxamidoadenosines as Potent and Selective Agonists of the A2A Adenosine Receptor

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.5b00215 ◽

2015 ◽

Vol 58 (7) ◽

pp. 3253-3267 ◽

Cited By ~ 12

Author(s):

Delia Preti ◽

Pier Giovanni Baraldi ◽

Giulia Saponaro ◽

Romeo Romagnoli ◽

Mojgan Aghazadeh Tabrizi ◽

...

Keyword(s):

Adenosine Receptor ◽

Biological Evaluation ◽

A2a Adenosine Receptor ◽

Design Synthesis ◽

Selective Agonists ◽

Design, synthesis and biological evaluation of piperazine analogues as CB1 cannabinoid receptor ligands

Bioorganic & Medicinal Chemistry ◽

10.1016/j.bmc.2008.01.023 ◽

2008 ◽

Vol 16 (7) ◽

pp. 4035-4051 ◽

Cited By ~ 11

Author(s):

Kwang-Seop Song ◽

Sung-Han Lee ◽

Hyun Ji Chun ◽

Jong Yup Kim ◽

Myung Eun Jung ◽

...

Keyword(s):

Cannabinoid Receptor ◽

Biological Evaluation ◽

Receptor Ligands ◽

Design Synthesis ◽

Cb1 Cannabinoid Receptor ◽

Design, synthesis and biological evaluation of bitopic arylpiperazine-hexahydro-pyrazinoquinolines as preferential dopamine D3 receptor ligands

Bioorganic Chemistry ◽

10.1016/j.bioorg.2017.12.026 ◽

2018 ◽

Vol 77 ◽

pp. 125-135

Author(s):

Benhua Zhou ◽

Min Ji ◽

Jin Cai

Keyword(s):

Biological Evaluation ◽

Dopamine D3 Receptor ◽

D3 Receptor ◽

Receptor Ligands ◽

Design Synthesis ◽

Dopamine D3 ◽

Design, Synthesis and Biological Evaluation of Novel Benzopyran Sulfonamide Derivatives as 5-HT6 Receptor Ligands

Asian Journal of Chemistry ◽

10.14233/ajchem.2015.17783 ◽

2015 ◽

Vol 27 (6) ◽

pp. 2117-2124 ◽

Cited By ~ 1

Author(s):

Ramakrishna V.S. Nirogi ◽

Rajeshkumar Badange ◽

Veena Reballi ◽

Mukkanti Khagga

Keyword(s):

Biological Evaluation ◽

Receptor Ligands ◽

Design Synthesis ◽

Pyrimidin-8-on[2,1-f]theophylline-9-alkylcarboxylic acids amides as A1 and A2A adenosine receptor ligands

Il Farmaco ◽

10.1016/s0014-827x(03)00066-1 ◽

2003 ◽

Vol 58 (6) ◽

pp. 439-444 ◽

Cited By ~ 3

Author(s):

Omeran Fhid ◽

Maciej Pawlowski ◽

Slawomir Jurczyk ◽

Christa E. Muller ◽

Britta Schumacher

Keyword(s):

Adenosine Receptor ◽

Receptor Ligands ◽

A2a Adenosine Receptor ◽

Synthesis of New 2-Phenyladenines and 2-Phenylpteridines and Biological Evaluation as Adenosine Receptor Ligands.

ChemInform ◽

10.1002/chin.200725210 ◽

2007 ◽

Vol 38 (25) ◽

Author(s):

Irene Giorgi ◽

Giuliana Biagi ◽

Oreste Livi ◽

Michele Leonardi ◽

Valerio Scartoni ◽

...

Keyword(s):

Adenosine Receptor ◽

Biological Evaluation ◽

Receptor Ligands ◽

Synthesis and Biological Evaluation of Metabolites of 2-n-Butyl-9-methyl-8-[1,2,3]triazol-2-yl-9H-purin-6-ylamine (ST1535), A Potent Antagonist of the A2A Adenosine Receptor for the Treatment of Parkinson’s Disease

Journal of Medicinal Chemistry ◽

10.1021/jm400491x ◽

2013 ◽

Vol 56 (13) ◽

pp. 5456-5463 ◽

Cited By ~ 13

Author(s):

Giovanni Piersanti ◽

Francesca Bartoccini ◽

Simone Lucarini ◽

Walter Cabri ◽

Maria Antonietta Stasi ◽

...

Keyword(s):

Parkinson’S Disease ◽

Parkinson's Disease ◽

Adenosine Receptor ◽

Biological Evaluation ◽

A2a Adenosine Receptor ◽

Potent Antagonist ◽

8-Substituted-9-deazaxanthines as adenosine receptor ligands: design, synthesis and structure-affinity relationships at A2B

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2004.07.008 ◽

2004 ◽

Vol 39 (10) ◽

pp. 879-887 ◽

Cited By ~ 19

Author(s):

Angelo Carotti ◽

Angela Stefanachi ◽

Enrique Raviña ◽

Eddy Sotelo ◽

Maria Isabel Loza ◽

...

Keyword(s):

Adenosine Receptor ◽

Receptor Ligands ◽

Design Synthesis ◽

Predictive 3D-Quantitative Structure-Activity Relationship for A1 and A2A Adenosine Receptor Ligands

QSAR & Combinatorial Science ◽

10.1002/qsar.200910047 ◽

2009 ◽

Vol 28 (11-12) ◽

pp. 1442-1454 ◽

Cited By ~ 1

Author(s):

Olga Yuzlenko ◽

Anna Drabczyńska ◽

Katarzyna Kieć-Kononowicz

Keyword(s):

Adenosine Receptor ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Receptor Ligands ◽

A2a Adenosine Receptor ◽

Structure Activity ◽