Design, synthesis and structure-activity relationship studies of a focused library of pyrimidine moiety with anti-proliferative and anti-metastasis activities in triple negative breast cancer

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2017.08.067 ◽

2017 ◽

Vol 140 ◽

pp. 155-171 ◽

Cited By ~ 12

Author(s):

Dahong Yao ◽

Yuxin Zhou ◽

Lingjuan Zhu ◽

Liang Ouyang ◽

Jin Zhang ◽

...

Keyword(s):

Breast Cancer ◽

Triple Negative Breast Cancer ◽

Triple Negative ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Pyrimidine Moiety

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Design, synthesis and structure-activity relationship study of novel urea compounds as FGFR1 inhibitors to treat metastatic triple-negative breast cancer

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2020.112866 ◽

2021 ◽

Vol 209 ◽

pp. 112866

Author(s):

Md Ashraf-Uz-Zaman ◽

Sadisna Shahi ◽

Racheal Akwii ◽

Md Sanaullah Sajib ◽

Mohammad Jodeiri Farshbaf ◽

...

Keyword(s):

Breast Cancer ◽

Triple Negative Breast Cancer ◽

Triple Negative ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Relationship Study ◽

Urea Compounds

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Design, Synthesis, and Structure–Activity Relationship Studies of 3-(Phenylethynyl)-1H-pyrazolo[3,4-d]pyrimidin-4-amine Derivatives as a New Class of Src Inhibitors with Potent Activities in Models of Triple Negative Breast Cancer

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.5b00270 ◽

2015 ◽

Vol 58 (9) ◽

pp. 3957-3974 ◽

Cited By ~ 26

Author(s):

Chun-Hui Zhang ◽

Ming-Wu Zheng ◽

Ya-Ping Li ◽

Xing-Dong Lin ◽

Mei Huang ◽

...

Keyword(s):

Breast Cancer ◽

Triple Negative Breast Cancer ◽

Triple Negative ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Design Synthesis ◽

New Class ◽

Structure Activity

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Structure-activity relationship studies on Bax activator SMBA1 for the treatment of ER-positive and triple-negative breast cancer

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.06.004 ◽

2019 ◽

Vol 178 ◽

pp. 589-605 ◽

Cited By ~ 1

Author(s):

Gang Liu ◽

Tao Yin ◽

Hyejin Kim ◽

Chunyong Ding ◽

Zhuo Yu ◽

...

Keyword(s):

Breast Cancer ◽

Triple Negative Breast Cancer ◽

Triple Negative ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity ◽

Er Positive

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Synthesis and structure-activity relationship studies of parthenolide derivatives as potential anti-triple negative breast cancer agents

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2019.01.058 ◽

2019 ◽

Vol 166 ◽

pp. 445-469 ◽

Cited By ~ 9

Author(s):

Weizhi Ge ◽

Xin Hao ◽

Fangzhi Han ◽

Zhongquan Liu ◽

Tianpeng Wang ◽

...

Keyword(s):

Breast Cancer ◽

Triple Negative Breast Cancer ◽

Triple Negative ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Structure Activity

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Abstract 4204: Structure-activity relationship of diphenylamine derivatives to target epithelial to mesenchymal transition in triple negative breast cancer

10.1158/1538-7445.am2018-4204 ◽

2018 ◽

Author(s):

Akshita B. Bhatt ◽

Thomas D. Wright ◽

Katie Anna ◽

Mohit Gupta ◽

Patrick Flaherty ◽

...

Keyword(s):

Breast Cancer ◽

Triple Negative Breast Cancer ◽

Epithelial To Mesenchymal Transition ◽

Triple Negative ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Mesenchymal Transition ◽

Structure Activity ◽

Relationship Of

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Design, synthesis and structure-activity relationship of a focused library of β-phenylalanine derivatives as novel eEF2K inhibitors with apoptosis-inducing mechanisms in breast cancer

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2017.11.065 ◽

2018 ◽

Vol 143 ◽

pp. 402-418 ◽

Cited By ~ 9

Author(s):

Yongzhi Guo ◽

Yuqian Zhao ◽

Guan Wang ◽

Yi Chen ◽

Yingnan Jiang ◽

...

Keyword(s):

Breast Cancer ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Relationship Of

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Design, Synthesis and Structure-Activity Relationship Studies of Novel 4 (1-adamantyl) Phenyl Analogues as HIF-1α Inhibitors

Medicinal Chemistry ◽

10.2174/1573406412666151109113007 ◽

2016 ◽

Vol 12 (4) ◽

pp. 338-346 ◽

Cited By ~ 2

Author(s):

Yan Xia ◽

Qiong Duan ◽

Bao-Hua Zhao ◽

Dong-Feng Li ◽

Rui-Bin Hou

Keyword(s):

Structure Activity Relationship ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity

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Design, synthesis, biological evaluation and structure-activity relationship study of quinazolin-4(3H)-one derivatives as novel USP7 inhibitors

European Journal of Medicinal Chemistry ◽

10.1016/j.ejmech.2021.113291 ◽

2021 ◽

pp. 113291

Author(s):

Peng Li ◽

Ying Liu ◽

Hua Yang ◽

Hong-Min Liu

Keyword(s):

Structure Activity Relationship ◽

Biological Evaluation ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Relationship Study

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New substituted pyrazolones and dipyrazolotriazines as promising tyrosyl-tRNA synthetase and peroxiredoxin-5 inhibitors: Design, synthesis, molecular docking and structure-activity relationship (SAR) analysis

Bioorganic Chemistry ◽

10.1016/j.bioorg.2021.104704 ◽

2021 ◽

Vol 109 ◽

pp. 104704

Author(s):

Ismail M.M. Othman ◽

Mohamed A.M. Gad-Elkareem ◽

El Hassane Anouar ◽

Kaïss Aouadi ◽

Mejdi Snoussi ◽

...

Keyword(s):

Molecular Docking ◽

Structure Activity Relationship ◽

Trna Synthetase ◽

Activity Relationship ◽

Design Synthesis ◽

Structure Activity ◽

Sar Analysis

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Antileishmanial Chalcones: Statistical Design, Synthesis, and Three-Dimensional Quantitative Structure−Activity Relationship Analysis

Journal of Medicinal Chemistry ◽

10.1021/jm980410m ◽

1998 ◽

Vol 41 (24) ◽

pp. 4819-4832 ◽

Cited By ~ 183

Author(s):

Simon Feldbæk Nielsen ◽

Søren Brøgger Christensen ◽

Gabriele Cruciani ◽

Arsalan Kharazmi ◽

Tommy Liljefors

Keyword(s):

Three Dimensional ◽

Statistical Design ◽

Quantitative Structure Activity Relationship ◽

Structure Activity Relationship ◽

Activity Relationship ◽

Quantitative Structure ◽

Design Synthesis ◽

Relationship Analysis ◽

Structure Activity

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