Prediction of preterm labour from a single blood test: The role of the endocannabinoid system in predicting preterm birth in high-risk women

2019 ◽  
Vol 243 ◽  
pp. 1-6 ◽  
Author(s):  
P. Bachkangi ◽  
A.H. Taylor ◽  
Monica Bari ◽  
Mauro Maccarrone ◽  
Justin C. Konje
Keyword(s):  
Preterm Birth ◽  
High Risk ◽  
Blood Test ◽  
Preterm Labour ◽  
Endocannabinoid System ◽  
High Risk Women

scholarly journals Transvaginal ultrasonographic assessment of cervical length in prediction of preterm labour in high risk asymptomatic women

2018 ◽  
Vol 7 (12) ◽  
pp. 4981
Author(s):  
Seeniamal Pushparaj ◽  
Prasanna Nagaraj
Keyword(s):  
Preterm Birth ◽  
High Risk ◽  
Preterm Labour ◽  
Cost Effective ◽  
Cervical Length ◽  
Length Measurement ◽  
Spontaneous Preterm Birth ◽  
High Risk Women ◽  
Asymptomatic Women ◽  
Cervical Length Measurement

Background: Preterm birth is an important cause of perinatal morbidity and mortality and has long term health implications. Aim of this study was to predict preterm labour by Transvaginal ultrasonographic cervical length measurement in high risk asymptomatic women which may help in decision making in managing these women.Methods: This study was conducted in Department of Obstetrics and Gynecology, Mahathma Gandhi Memorial Government Hospital, Trichy from August 2016 to September 2017 in 130 antenatal women with high risk factors such as prior spontaneous preterm birth, miscarriage. Transvaginal cervical length was measured and Gestational age at which delivery occurred was correlated and results were analyzed.Results: In present study, sensitivity of transvaginal cervical length measurement (cut off cervical length <25 mm) was 70.9% and specificity was 63% in prediction of preterm labour in high risk asymptomatic women. Positive and negative predictive value of cervical length in predicting preterm labour were 63.7 %and 70% respectively.Conclusions: Transvaginal cervical length measurement can be combined with anomaly scan in high risk women to predict preterm labor and is objective, reproducible and cost effective.

scholarly journals Evaluation of fetal fibronectin rapid bedside test as a predictor of preterm labour: a prospective study

2019 ◽  
Vol 8 (9) ◽  
pp. 3447
Author(s):  
Kusum Dogra ◽  
Meenakshi Tanwar
Keyword(s):  
High Risk ◽  
Preterm Delivery ◽  
Preterm Labour ◽  
Public Health Issue ◽  
Dipstick Test ◽  
Fetal Fibronectin ◽  
High Risk Women ◽  
Bedside Test ◽  
Vaginal Secretions ◽  
Sensitivity Specificity

Background: Preterm birth defined as birth before 37 weeks of gestation is a significant public health issue. Identification of patients at risk of preterm labour while ruling out those who are not is a fundamental but challenging goal for clinicians. This study was done to evaluate bed side dipstick test for detecting fetal fibronectin in cervico-vaginal secretions as a predictor of preterm delivery in symptomatic and asymptomatic high risk group.Methods: This was a hospital based prospective, double blinded study. We enrolled 100 pregnant women presenting with or without symptoms of preterm delivery, between 20 and 35 weeks of gestation. A rapid bed side dipstick test was performed to detect FFN in cervico-vaginal secretions of all enrolled women (symptomatic and asymptomatic high risk women) and results were evaluated for prediction of preterm labour. Qualitative data were analyzed by using Chi-square and Fisher’s exact test and quantitative data were analyzed by using unpaired Student’s t test and Mann-Whitney test. P value < 0.05 was considered significant.Results: In symptomatic group sensitivity, specificity, PPV and NPV of FFN test in predicting delivery within 48 hours, 7days 14days and preterm delivery was 100%, 63.2%, 46.2%, 100%; 100%, 72.7%, 65.4%, 100%; 100%, 75%, 69.2%, 100%; 80%, 76%, 76.9%, 79.2% respectively. In asymptomatic high risk group, sensitivity, specificity, PPV and NPV of FFN test in predicting preterm delivery (<37weeks) was 0%, 87.5%, 0%, 77.8%.Conclusions: The high negative predictive value may be of value in avoiding unnecessary interventions with potentially hazardous medications and identifying symptomatic women who are not in true labour and also allaying anxiety of asymptomatic high risk women.

scholarly journals 463: Second trimester normal cervical length in asymptomatic high-risk women: Role of the cervical consistency index

2019 ◽  
Vol 220 (1) ◽  
pp. S310
Author(s):  
Montse Palacio ◽  
Júlia Ponce ◽  
Leticia Benítez ◽  
Clara Murillo ◽  
Teresa Cobo ◽  
...  
Keyword(s):  
High Risk ◽  
Cervical Length ◽  
Consistency Index ◽  
Second Trimester ◽  
High Risk Women

Multicenter Randomized Trial of Cerclage for Preterm Birth Prevention in High-Risk Women With Shortened Midtrimester Cervical Length

2010 ◽  
Vol 65 (2) ◽  
pp. 73-74
Author(s):  
John Owen ◽  
Gary Hankins ◽  
Jay D. Iams ◽  
Vincenzo Berghella ◽  
Jeanne S. Sheffield ◽  
...  
Keyword(s):  
Preterm Birth ◽  
High Risk ◽  
Randomized Trial ◽  
Cervical Length ◽  
High Risk Women ◽  
Multicenter Randomized Trial
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