Has the QUASAR study on Dukes' B colorectal cancer impacted on rates of post operative adjuvant chemotherapy?

2008 ◽  
Vol 34 (10) ◽  
pp. 1168
Author(s):  
Andrew Wigham ◽  
S. Irukulla ◽  
L. Malhas ◽  
S. Essapen ◽  
D. Donaldson
Keyword(s):  
Colorectal Cancer ◽  
Adjuvant Chemotherapy

A Tale of Two Colons and Two Cancers

Swiss Surgery ◽  
2003 ◽  
Vol 9 (1) ◽  
pp. 3-7 ◽  
Author(s):  
Gervaz ◽  
Bühler ◽  
Scheiwiller ◽  
Morel
Keyword(s):  
Colorectal Cancer ◽  
Colon Cancer ◽  
Adjuvant Chemotherapy ◽  
Splenic Flexure ◽  
Chromosomal Instability ◽  
Proximal Colon ◽  
Colorectal Carcinogenesis ◽  
Physiological Data ◽  
Central Hypothesis ◽  
Group Stratification

The central hypothesis explored in this paper is that colorectal cancer (CRC) is a heterogeneous disease. The initial clue to this heterogeneity was provided by genetic findings; however, embryological and physiological data had previously been gathered, showing that proximal (in relation to the splenic flexure) and distal parts of the colon represent distinct entities. Molecular biologists have identified two distinct pathways, microsatellite instability (MSI) and chromosomal instability (CIN), which are involved in CRC progression. In summary, there may be not one, but two colons and two types of colorectal carcinogenesis, with distinct clinical outcome. The implications for the clinicians are two-folds; 1) tumors originating from the proximal colon have a better prognosis due to a high percentage of MSI-positive lesions; and 2) location of the neoplasm in reference to the splenic flexure should be documented before group stratification in future trials of adjuvant chemotherapy in patients with stage II and III colon cancer.

The efficacy of adjuvant chemotherapy for resected high-risk stage II and stage III colorectal cancer in frail patients

2021 ◽  
Author(s):  
Kosuke Mima ◽  
Nobutomo Miyanari ◽  
Keisuke Kosumi ◽  
Takuya Tajiri ◽  
Kosuke Kanemitsu ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
High Risk ◽  
Adjuvant Chemotherapy ◽  
Stage Ii ◽  
Stage Iii ◽  
Frail Patients

scholarly journals Colorectal cancer adjuvant chemotherapy trends among a nonelderly veteran cohort at a southern veterans health administration

2021 ◽  
Author(s):  
Richard L. Martin ◽  
Gretchen C. Edwards ◽  
Lauren R. Samuels ◽  
Cathy Eng ◽  
Christianne L. Roumie
Keyword(s):  
Colorectal Cancer ◽  
Adjuvant Chemotherapy ◽  
Veterans Health Administration ◽  
Veterans Health ◽  
Health Administration

Adjuvant chemotherapy for colorectal cancer — is it working and who is receiving it?

2000 ◽  
Vol 118 (4) ◽  
pp. A1397
Author(s):  
Anne Marie Lennon ◽  
Ann White ◽  
Kathy Sheehan ◽  
Judith Reidy ◽  
James J. Murphy ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Adjuvant Chemotherapy

An anticancer drug sensitivity test to determine the effectiveness of UFT as postoperative adjuvant chemotherapy for patients with stage III colorectal cancer

Surgery ◽  
2007 ◽  
Vol 142 (5) ◽  
pp. 741-748 ◽  
Author(s):  
Akiko Isogai ◽  
Masaki Nagaya ◽  
Hiromitsu Matsuoka ◽  
Taiji Watanabe ◽  
Satoshi Tsukikawa ◽  
...  
Keyword(s):  
Colorectal Cancer ◽  
Adjuvant Chemotherapy ◽  
Anticancer Drug ◽  
Drug Sensitivity ◽  
Sensitivity Test ◽  
Stage Iii ◽  
Postoperative Adjuvant Chemotherapy ◽  
Drug Sensitivity Test

scholarly journals Sigmoid Carcinoma in an Inguinal Hernia: A Blessing in Disguise?

2013 ◽  
Vol 2013 ◽  
pp. 1-3
Author(s):  
P. B. Salemans ◽  
G. F. Vles ◽  
S. A. F. Fransen ◽  
R. M. Smeenk
Keyword(s):  
Colorectal Cancer ◽  
Case Report ◽  
Inguinal Hernia ◽  
Adjuvant Chemotherapy ◽  
Sigmoid Resection ◽  
Oncological Resection ◽  
Sigmoid Carcinoma

Colorectal cancer is a rising problem, as the incidence increases with age. In most cases the goal of treatment is oncological resection followed by adjuvant chemotherapy in order to optimize the survival. In this case report we present a 93-year-old patient with a sigmoid carcinoma inside an irreducible inguinal hernia, which was diagnosed prior to surgery. We chose to perform a sigmoid resection through an oblique inguinal incision as a safer alternative to laparotomy.

Sign in / Sign up

Export Citation Format

Share Document