scholarly journals Case report: Bilateral emphysematous pyelonephritis with pneumatosis intestinalis

2021 ◽  
pp. 101895
Author(s):  
Maria D'Amico ◽  
Joseph Izes ◽  
Akhil Das
2021 ◽  
Vol 15 (1) ◽  
Author(s):  
M. C. Martín-Soberón ◽  
S. Ruiz ◽  
G. De Velasco ◽  
R. Yarza ◽  
A. Carretero ◽  
...  

Abstract Background Pneumatosis intestinalis (PI) is a rare entity which refers to the presence of gas within the wall of the small bowel or colon which is a radiographic sign. The etiology and clinical presentation are variable. Patients with PI may present either with chronic mild non-specific symptoms or with acute abdominal pain with peritonitis. Some cases of intestinal pneumatosis have been reported as adverse events of new oncological treatments such as targeted therapies that are widely used in multiple tumors. Case presentation A 59-year-old caucasian female with radioactive iodine-refractory metastatic thyroid papillary carcinoma with BRAFV600E mutation was treated with dabrafenib and trametinib as a compassionate use. After 4 months treatment, positron emission tomography–computed tomography (PET–CT) showed PI. At the time of diagnosis, the patient was asymptomatic without signs of peritonitis. The initial treatment was conservative and no specific treatment for PI was needed. Unfortunately, after dabrafenib–trametinib withdrawal, the patient developed tumor progression with significant clinical worsening. Conclusions This case report is, in our knowledge, the first description of PI in a patient treated with dabrafenib–trametinib. Conservative treatment is feasible if there are no abdominal symptoms.


2021 ◽  
Vol 38 ◽  
pp. 101685
Author(s):  
Albara Hariri ◽  
Abdulhkam Aljarbou ◽  
Khalid Albalawi ◽  
Saad Alqasem ◽  
Ibrahim Alowidah ◽  
...  

2011 ◽  
Vol 2011 ◽  
pp. 1-5 ◽  
Author(s):  
Sean Donovan ◽  
Joseph Cernigliaro ◽  
Nancy Dawson

Pneumatosis intestinalis (PI), defined as gas within the bowel wall, is an uncommon radiographic sign which can represent a wide spectrum of diseases and a variety of underlying diagnoses. Because its etiology can vary greatly, management of PI ranges from surgical intervention to outpatient observation (see, Greenstein et al. (2007), Morris et al. (2008), and Peter et al. (2003)). Since PI is infrequently encountered, clinicians may be unfamiliar with its diagnosis and management; this unfamiliarity, combined with the potential necessity for urgent intervention, may place the clinician confronted with PI in a precarious medical scenario. We present a case of pneumatosis intestinalis in a patient who posed a particularly challenging diagnostic dilemma for the primary team. Furthermore, we explore the differential diagnosis prior to revealing the intervention offered to our patient; our concise yet inclusive differential and thought process for rapid evaluation may be of benefit to clinicians presented with similar clinical scenarios.


1993 ◽  
Vol 10 (2) ◽  
pp. 537
Author(s):  
Hyun Dae Yoon ◽  
Kyu Chang Won ◽  
Chan Woo Lee ◽  
In Ho Jo ◽  
Hyung Woo Lee ◽  
...  

2021 ◽  
Vol Volume 13 ◽  
pp. 375-379
Author(s):  
Michał Godzisz ◽  
Przemysław Mitura ◽  
Damian Widz ◽  
Damian Sudoł ◽  
Iga Kuliniec ◽  
...  

2018 ◽  
Vol 7 (50) ◽  
pp. 5400-5401
Author(s):  
Shrijit Kumar ◽  
Hemendra Singh ◽  
Yogesh Jhamb ◽  
Kaza R. C. M ◽  
Aditya Arya

Cases Journal ◽  
2008 ◽  
Vol 1 (1) ◽  
pp. 192 ◽  
Author(s):  
Samuel R Vollans ◽  
Ranjit Sehjal ◽  
James A Forster ◽  
Karol M Rogawski

2019 ◽  
Vol 58 ◽  
pp. 174-177 ◽  
Author(s):  
Carlos Jose Perez Rivera ◽  
Nathaly Alexandra Ramirez ◽  
Alejandro Gonzalez-Orozco ◽  
Isabella Caicedo ◽  
Paulo Cabrera

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