clinical entity
Recently Published Documents


TOTAL DOCUMENTS

1887
(FIVE YEARS 346)

H-INDEX

71
(FIVE YEARS 7)

2022 ◽  
Vol 23 (2) ◽  
pp. 786
Author(s):  
Gracia Fahed ◽  
Laurence Aoun ◽  
Morgan Bou Zerdan ◽  
Sabine Allam ◽  
Maroun Bou Zerdan ◽  
...  

Metabolic syndrome (MetS) forms a cluster of metabolic dysregulations including insulin resistance, atherogenic dyslipidemia, central obesity, and hypertension. The pathogenesis of MetS encompasses multiple genetic and acquired entities that fall under the umbrella of insulin resistance and chronic low-grade inflammation. If left untreated, MetS is significantly associated with an increased risk of developing diabetes and cardiovascular diseases (CVDs). Given that CVDs constitute by far the leading cause of morbidity and mortality worldwide, it has become essential to investigate the role played by MetS in this context to reduce the heavy burden of the disease. As such, and while MetS relatively constitutes a novel clinical entity, the extent of research about the disease has been exponentially growing in the past few decades. However, many aspects of this clinical entity are still not completely understood, and many questions remain unanswered to date. In this review, we provide a historical background and highlight the epidemiology of MetS. We also discuss the current and latest knowledge about the histopathology and pathophysiology of the disease. Finally, we summarize the most recent updates about the management and the prevention of this clinical syndrome.


Author(s):  
Nair Chithira V. ◽  
Sathyapalan Dipu T. ◽  
Moni Merlin ◽  
Suresh Akshaya ◽  
Roshni Pushpa Raghavan
Keyword(s):  

2022 ◽  
Vol 81 ◽  
pp. 72-78
Author(s):  
Amit B. Desai ◽  
Prasanna Vibhute ◽  
Alok A. Bhatt
Keyword(s):  

2021 ◽  
Vol 2 (S1) ◽  
pp. 1-3
Author(s):  
Diallo Kadidiatou Folly ◽  
Dyatta Mayombo Kévin ◽  
Atsame Ebang Gabrielle ◽  
Ipouka Doussiemou Sergina ◽  
Nguele Ndjota ◽  
...  

Introduction: Schwannoma of the glans is a rare clinical entity. The diagnosis is histological. Treatment is surgical, with complete excision. The authors report this rare case encountered at the University Hospital of Libreville in order to identify its clinical and therapeutic characteristics. Observation: Mr. I.B, 50 years old, with no medical-surgical history, consulted for swelling of the glans evolving for 06 years, preventing coitus. He reported a notion of poor healing from an acorn sore after the trouser fly was closed. The diagnostic suspicion was a glans keloid. A complete resection was performed. Histologic examination favored a glans schwannoma. Healing was effective on D7 postoperatively. Erectile functions have been preserved. Conclusion: The glans schwannoma is rare. Surgical treatment gives good results.


2021 ◽  
pp. 1-3
Author(s):  
Stephanie L. Harrison ◽  
Benjamin J.R. Buckley ◽  
Riccardo Proietti ◽  
Gregory Y. H. Lip

2021 ◽  
Vol 23 (Supplement_G) ◽  
Author(s):  
Dario Calderone ◽  
Maria Sara Mauro ◽  
Marco Legnazzi ◽  
Federica Agnello ◽  
Lorenzo Scalia ◽  
...  

Abstract Aims Abrupt oppressive chest pain is a common reason of emergency department’s access. An accurate assessment of the clinical setting is needed to ensure the patient the correct management. This includes a good anamnesis, physical examination, electrocardiogram (ECG) and cardiac biomarkers evaluation. Wellens syndrome is a clinical entity characterized by acute chest pain, normal or minimal elevation of cardiac biomarker, specific ECG changes with no ST elevation or Q-waves. The ECG modifications contemplate: biphasic T waves in lead V2 and V3 (type A) initially positive and subsequent negative or deep and symmetrically inverted T waves in anterior leads (Type B, more often V1–V4). Recognizing these patterns can be so challenging for physician in emergency departments, especially in Type A, and failure in diagnosis can lead to deleterious outcomes. In fact, Wellens syndrome can be considered as a pre-infarction state that needs immediate intervention: if not treated appropriately, about 75% of patients can suffer anterior myocardial infarction due to a stenosis of left anterior descending (LAD) artery. Methods A 55-year-old male with hyperlipidaemia and a family history of cardiovascular disease, presented to emergency department with abrupt oppressive chest pain after mild physical effort. At presentation he presented a typical ECG of Wellens syndrome type A with negative cardiac biomarkers. His GRACE (Global Registry of Acute Coronary Events) score was 72 and his thrombolysis in myocardial infarction (TIMI) was 2. At second blood sample cardiac biomarkers was mildly higher than upper limit of normal. Results Despite low grade on risk stratification he immediately underwent coronary angiography, who resulted in a subocclusive stenosis from ostium to the medium tract of LAD. PCI was subsequently taken with implantation of TWO drug eluting stent (DES). After 3 days he was discharged asymptomatic and in optical medical therapy. Conclusions Wellens syndrome is a rare clinical entity that must be considered as a pre- infarction state difficult to individuate. Conventional management in these patients utilizing typical risk stratification scores may not be appropriate. In this context an early diagnosis of ECG patterns it’s crucial, in order to provide an urgent percutaneous intervention. Failure in recognition of signs and symptoms of Wellens syndrome can lead to disastrous outcome due to a critical, vulnerable, stenosis on proxymal LAD and to a possible imminent large anterior myocardial infarction.


2021 ◽  
Vol 345 ◽  
pp. 27-28
Author(s):  
N.A. Muhammad Zawawi ◽  
I.M. Amran ◽  
M.N. Mohd Yaakob ◽  
F.A. Abdul Aziz

2021 ◽  
Vol 12 (2) ◽  
pp. 598-602
Author(s):  
Zenab Alami ◽  
Amina Bouziane ◽  
Wissal Hassani ◽  
Fatima Zahrae Farhane ◽  
Touria Bouhafa

Paratesticular Rhabdomyosarcoma is a rare mesenchymal tumor. The Alveolar variant is the one with the worse prognosis. It comprehend 20% of cases. The treatment is multimodal combining surgery, chemotherapy and radiotherapy. Depending on the extent of disease and the staging group, the approach of treatment is different. Here we report the case of an alveolar Paratesticular rhabdomyosarcoma and review the literature regarding this unusual clinical entity.


Sign in / Sign up

Export Citation Format

Share Document