Primary localized amyloidosis of the ureter with osseous metaplasia presenting as a suspicious ureteral mass

The purpose of this article is to present a rare case of localized, solitary amyloid tumor of tongue base and emphasize some of the characteristic features of challenging clinical and histopathologic diagnosis. In this paper, we focused on the clinical and pathological specifications of this rare tumor, so any unnecessary examinations or measures may be spared. Negative staining of amyloid material with AAC and osseous metaplasia noted in the histopathologic examination may not be thought as definite criteria for localized amyloidosis, but a supporter of localized, solitary amyloid tumor diagnosis.

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Macular amyloidosis with localized amyloidosis of upper air passages

Archives of Dermatology ◽

10.1001/archderm.111.8.1017 ◽

1975 ◽

Vol 111 (8) ◽

pp. 1017-1019 ◽

Cited By ~ 3

Author(s):

H. R. Gottschalk

Keyword(s):

Localized Amyloidosis ◽

Macular Amyloidosis

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Primary Localized Amyloidosis in Extraocular Muscles

Journal of the Korean Ophthalmological Society ◽

10.3341/jkos.2019.60.12.1301 ◽

2019 ◽

Vol 60 (12) ◽

pp. 1301 ◽

Cited By ~ 1

Author(s):

Sun Hyup Han ◽

Yoon-Duck Kim ◽

Kyung In Woo

Keyword(s):

Extraocular Muscles ◽

Localized Amyloidosis

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Incidentally Discovered Osseous Metaplasia Within High-grade Urothelial Carcinoma of the Bladder

Urology ◽

10.1016/j.urology.2011.06.043 ◽

2012 ◽

Vol 79 (4) ◽

pp. e59-e60 ◽

Cited By ~ 3

Author(s):

Anne G. Dudley ◽

Jeffrey J. Tomaszewski ◽

Amber H. Hughes ◽

Benjamin J. Davies

Keyword(s):

Urothelial Carcinoma ◽

Osseous Metaplasia ◽

High Grade ◽

Carcinoma Of The Bladder

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Imaging of endometrial osseous metaplasia—an uncommon but treatable cause of infertility

Middle East Fertility Society Journal ◽

10.1186/s43043-020-00045-0 ◽

2020 ◽

Vol 25 (1) ◽

Author(s):

Abdul Haseeb Wani ◽

Arshed Hussain Parry ◽

Imza Feroz ◽

Majid Jehangir ◽

Masarat Rashid

Keyword(s):

Inflammatory Cells ◽

Osseous Metaplasia ◽

Dystrophic Calcification ◽

Non Invasive ◽

Dilatation And Curettage ◽

Clinical Scenarios ◽

Uncommon Condition ◽

Urinary Tuberculosis ◽

Hypointense Signal ◽

Metaplastic Ossification

Abstract Background Endometrial osseous metaplasia (EOM) is an uncommon condition characterised by metaplastic transformation of endometrial tissue into osteoblasts (mature or immature bone in the endometrium). Etiopathogenesis of EOM is explained by multiple putative mechanisms like dystrophic calcification, metaplastic ossification, retained foetal bones after abortions and genito-urinary tuberculosis. EOM has varied clinical presentation ranging from patient being asymptomatic to secondary infertility. Although hysteroscopy is the gold standard for its diagnosis and treatment, non-invasive imaging comprising chiefly of ultrasonography (USG) is increasingly becoming the mainstay of diagnosis. We aim to present the imaging findings in EOM to acquaint radiologists and gynaecologists with this condition to avert misdiagnosis of this uncommon yet treatable cause of infertility. Results Mean age of patients was 31.4 ± 5.4 (S.D) years. USG revealed linear or tubular densely echogenic endometrium with posterior acoustic shadowing in all the 14 patients. MRI in 3 patients revealed diffuse or patchy areas of T1W and T2W hypointense signal intensity with unilateral (n = 2) and bilateral (n = 1) ovarian cysts. One patient who underwent CT scan revealed dense endometrial calcification. Histopathologic examination (HPE) revealed lamellar (n = 6) or trabecular (n = 4) bone within endometrium (EOM) and inflammatory cells with calcification in four patients (calcific endometritis). Twelve patients conceived after dilatation and curettage within 15 months. Conclusion Familiarity with the imaging appearances of EOM is indispensable to clinch this diagnosis and avert misdiagnosis of this rare but potentially treatable cause of infertility. USG is usually sufficient for diagnosis. MRI and CT are only supplementary tools in difficult clinical scenarios.

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GASTRIC CARCINOMA WITH OSSEOUS METAPLASIA IN A DOG

Archives of Veterinary Science ◽

10.5380/avs.v17i3.22798 ◽

2012 ◽

Vol 17 (3) ◽

Cited By ~ 1

Author(s):

Irina Ferraz Amorim ◽

Celia Lopes ◽

Rui M Gil da Costa ◽

Augusto MR Faustino ◽

Fatima Gartner ◽

...

Keyword(s):

Monoclonal Antibodies ◽

Epithelial Cells ◽

Gastric Carcinoma ◽

Heterotopic Ossification ◽

Bone Tissue ◽

Exploratory Laparotomy ◽

Osseous Metaplasia ◽

Mucin Production ◽

Positive Immunostaining ◽

Neoplastic Epithelial Cells

This report describes an unprecedented case of a gastric carcinoma with osseous metaplasia in a 8-year-old male standard poodle. An exploratory laparotomy revealed a firm yellowish nodular mass in the pyloric region. The lesion was surgically removed and submitted for current histological examination. Immunohistochemistry was performed employing monoclonal antibodies for pan-cytokeratin, vimentin, smooth muscular a-actin and BMP-2/4. The mass consisted in neoplastic proliferation of epithelial cells, arranged in a tubular or acinar pattern and supported by scirrhous stroma, with mucin production and multiple foci of heterotopic ossification. Neoplastic epithelial cells showed strong positive immunostaining for AE1/AE3 and BMP-2/4, although they were negative for both vimentin and a-actin. Histopathological findings suggested that the bone tissue may be primarily originated from neoplastic epithelial cells which directly circumscribe the osseous metaplasia foci.

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