Predicting Renal Function Outcomes After Partial and Radical Nephrectomy

2019 ◽  
Vol 75 (5) ◽  
pp. 766-772 ◽  
Author(s):  
Bimal Bhindi ◽  
Christine M. Lohse ◽  
Phillip J. Schulte ◽  
Ross J. Mason ◽  
John C. Cheville ◽  
...  
2021 ◽  
pp. 039156032098779
Author(s):  
Debansu Sarkar ◽  
Akash Agrawal ◽  
Dilip Kumar Pal

Introduction and objective: Nephrectomy leads to derangement of renal function and various adaptive changes by the remaining kidney over a period of time. This study is performed to evaluate the amount of derangement of renal function in donor and radical nephrectomy, how much the remaining kidney adapts over a period of time and the time taken for stabilisation of renal function. Method: A total of 60 patients who underwent nephrectomy (Radical/Donor) were followed up for 12 months with serial estimation of renal function and was compared with preoperative renal function. Data was analysed with statistical analysis. Result: Patients who underwent radical nephrectomy had 37% initial decline in renal function which was later stabilised at 19% lower than baseline value. Patient who underwent donor nephrectomy had initially 39% decline in renal function which was later stabilised at 24% lower than normal. Conclusion: Removal of functional renal tissue led to reduction of renal function. This decline is more evident in the initial post-operative period and then begin to stabilise over months. The greater is the amount of normal tissue removed, the greater is the reduction of renal function and more time it will take to stabilise, increasing overall morbidity of the patient. This study suggests that even patients with normal GFRs should be followed up postoperatively to determine their ultimate renal functional outcomes.


2020 ◽  
Vol 104 (9-10) ◽  
pp. 775-780 ◽  
Author(s):  
Julia Mühlbauer ◽  
Johannes de Gilde ◽  
Michael Mueller-Steinhardt ◽  
Stefan Porubsky ◽  
Margarete Walach ◽  
...  

2012 ◽  
Vol 187 (4S) ◽  
Author(s):  
Minato Yokoyama ◽  
Yasuhisa Fujii ◽  
Hideki Takeshita ◽  
Yasumasa Iimura ◽  
Kazutaka Saito ◽  
...  

2012 ◽  
Vol 11 (1) ◽  
pp. e90-e90a
Author(s):  
H. Takeshita ◽  
M. Yokoyama ◽  
Y. Fujii ◽  
K. Chiba ◽  
J. Ishioka ◽  
...  

2009 ◽  
Vol 9 ◽  
pp. 287-290 ◽  
Author(s):  
Matt S. Ashley ◽  
Gregory Moneta ◽  
Siamak Daneshmand

Pediatric renovascular hypertension is typically managed with revascularization, angioplasty, or radical nephrectomy. We describe the case of a 13-year-old boy with medically refractory renovascular hypertension who presented to our institution after a failed arterial bypass. Subsequent angiography and renin sampling of the segmental renal veins suggested that the lower pole of the kidney was affected exclusively by the relative hypoperfusion. We proceeded with an open partial nephrectomy in order to excise the affected region of the kidney, while preserving maximum renal function. The patient was normotensive off all antihypertensive medication and without complications 8 months postoperatively. We believe that partial nephrectomy is a reasonable treatment for children with renovascular hypertension secondary to segmental hypoperfusion, and it should be considered as alternative therapy.


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