Differences in Tumor VHL Mutation and Hypoxia-inducible Factor 2α Expression Between African American and White Patients with Clear Cell Renal Cell Carcinoma

White Patients

Intrinsic Genomic Differences Between African American and White Patients With Clear Cell Renal Cell Carcinoma

JAMA Oncology ◽

10.1001/jamaoncol.2016.0005 ◽

2016 ◽

Vol 2 (5) ◽

pp. 664 ◽

Cited By ~ 22

Author(s):

Bhavani Krishnan ◽

Tracy L. Rose ◽

Jordan Kardos ◽

Matthew I. Milowsky ◽

William Y. Kim

Keyword(s):

Renal Cell Carcinoma ◽

African American ◽

Cell Carcinoma ◽

Renal Cell ◽

Clear Cell ◽

White Patients

Faculty Opinions recommendation of Phase I Dose-Escalation Trial of PT2385, a First-in-Class Hypoxia-Inducible Factor-2α Antagonist in Patients With Previously Treated Advanced Clear Cell Renal Cell Carcinoma.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.732326989.793548439 ◽

2018 ◽

Author(s):

Camilo Jimenez

Keyword(s):

Renal Cell Carcinoma ◽

Phase I ◽

Cell Carcinoma ◽

Dose Escalation ◽

Renal Cell ◽

Clear Cell ◽

Previously Treated

Prognostic significance of hypoxia inducible factor-1α expression in patients with clear cell renal cell carcinoma

Molecular Medicine Reports ◽

10.3892/mmr.2018.8409 ◽

2018 ◽

Cited By ~ 2

Author(s):

Shuiqing Wu ◽

Fen Jiang ◽

Hongtao Wu ◽

Yinhuai Wang ◽

Ran Xu ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

Cell Carcinoma ◽

Renal Cell ◽

Clear Cell ◽

Prognostic Significance ◽

Hypoxia Inducible Factor 1Α

Poor prognosis and advanced clinicopathological features of clear cell renal cell carcinoma (ccRCC) are associated with cytoplasmic subcellular localisation of Hypoxia inducible factor-2α

European Journal of Cancer ◽

10.1016/j.ejca.2014.01.031 ◽

2014 ◽

Vol 50 (8) ◽

pp. 1531-1540 ◽

Cited By ~ 16

Author(s):

Nils Kroeger ◽

David B. Seligson ◽

Sabina Signoretti ◽

Hong Yu ◽

Clara E. Magyar ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

Cell Carcinoma ◽

Renal Cell ◽

Poor Prognosis ◽

Clear Cell ◽

Clinicopathological Features ◽

Subcellular Localisation ◽

Hypoxia-inducible factor (HIF)-prolyl hydroxylase 3 (PHD3) maintains high HIF2A mRNA levels in clear cell renal cell carcinoma

Journal of Biological Chemistry ◽

10.1074/jbc.ra118.004902 ◽

2019 ◽

Vol 294 (10) ◽

pp. 3760-3771 ◽

Cited By ~ 5

Author(s):

Petra Miikkulainen ◽

Heidi Högel ◽

Fatemeh Seyednasrollah ◽

Krista Rantanen ◽

Laura L. Elo ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

Cell Carcinoma ◽

Renal Cell ◽

Clear Cell ◽

Prolyl Hydroxylase ◽

Mrna Levels ◽

Hif Prolyl Hydroxylase

3-[(1S,2S,3R)-2,3-Difluoro-1-hydroxy-7-methylsulfonylindan-4-yl]oxy-5-fluorobenzonitrile (PT2977), a Hypoxia-Inducible Factor 2α (HIF-2α) Inhibitor for the Treatment of Clear Cell Renal Cell Carcinoma

Journal of Medicinal Chemistry ◽

10.1021/acs.jmedchem.9b00719 ◽

2019 ◽

Vol 62 (15) ◽

pp. 6876-6893 ◽

Cited By ~ 16

Author(s):

Rui Xu ◽

Keshi Wang ◽

James P. Rizzi ◽

Heli Huang ◽

Jonas A. Grina ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

Cell Carcinoma ◽

Renal Cell ◽

Clear Cell ◽

Identification of CDCP1 as a hypoxia-inducible factor 2α (HIF-2α) target gene that is associated with survival in clear cell renal cell carcinoma patients

Proceedings of the National Academy of Sciences ◽

10.1073/pnas.1222435110 ◽

2013 ◽

Vol 110 (9) ◽

pp. 3483-3488 ◽

Cited By ~ 38

Author(s):

Brooke M. Emerling ◽

Cyril H. Benes ◽

George Poulogiannis ◽

Eric L. Bell ◽

Kevin Courtney ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

Cell Carcinoma ◽

Renal Cell ◽

Target Gene ◽

Clear Cell ◽

656MO Phase II study of belzutifan (MK-6482), an oral hypoxia-inducible factor 2α (HIF-2α) inhibitor, plus cabozantinib for treatment of advanced clear cell renal cell carcinoma (ccRCC)

Annals of Oncology ◽

10.1016/j.annonc.2021.08.052 ◽

2021 ◽

Vol 32 ◽

pp. S681

Author(s):

D.F. McDermott ◽

T.K. Choueiri ◽

T.M. Bauer ◽

E. Arrowsmith ◽

A. Roy ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

Cell Carcinoma ◽

Phase Ii ◽

Renal Cell ◽

Clear Cell ◽

Phase Ii Study ◽

PD39-03 HYPOXIA-INDUCIBLE FACTOR (HIF) PATHWAY GENES PREDICT OVERALL SURVIVAL FOR METASTATIC CLEAR CELL RENAL CELL CARCINOMA

The Journal of Urology ◽

10.1097/ju.0000000000000918.03 ◽

2020 ◽

Vol 203 ◽

pp. e808-e809

Author(s):

Paige K Kuhlmann* ◽

Shengchen Su ◽

Sungyong You ◽

Devin Patel ◽

Brian Rini ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

Overall Survival ◽

Cell Carcinoma ◽

Renal Cell ◽

Clear Cell ◽

Hif Pathway

Hypoxia-Inducible Factor 1 in Clear Cell Renal Cell Carcinoma

Clinical Cancer Research ◽

10.1158/1078-0432.ccr-07-0411 ◽

2007 ◽

Vol 13 (24) ◽

pp. 7388-7393 ◽

Cited By ~ 128

Author(s):

T. Klatte ◽

D. B. Seligson ◽

S. B. Riggs ◽

J. T. Leppert ◽

M. K. Berkman ◽

...

Keyword(s):

Renal Cell Carcinoma ◽

Cell Carcinoma ◽

Renal Cell ◽

Clear Cell ◽

Hypoxia Inducible Factor 1