The effect of nerve growth factor on corneal nerve regeneration and dry eye after LASIK

2021 ◽  
pp. 108428
Author(s):  
Qianwen Gong ◽  
Shasha Zhang ◽  
Lu Jiang ◽  
Meng Lin ◽  
Zhiqiang Xu ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Nerve Regeneration ◽  
Dry Eye ◽  
Nerve Growth ◽  
Corneal Nerve

Nerve Growth Factor Enhances Nerve Regeneration through Fibronectin Grafts

1996 ◽  
Vol 21 (4) ◽  
pp. 514-522 ◽  
Author(s):  
I. H. WHITWORTH ◽  
R. A. BROWN ◽  
C. J. DORÉ ◽  
P. ANAND ◽  
C. J. GREEN ◽  
...  
Keyword(s):  
Image Analysis ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Schwann Cell ◽  
Nerve Regeneration ◽  
Axonal Regeneration ◽  
Cell Regeneration ◽  
Nerve Growth ◽  
Computerized Image Analysis ◽  
Immunohistochemical Techniques

Soluble fibronectin and nerve growth factor (NGF) promote axonal regeneration when placed in silicone tubes. We investigated the ability of orientated fibronectin mats to bind and release bioactive NGF and the possibility of augmenting axonal regeneration following axotomy by using fibronectin conduits impregnated with NGF. The release of NGF was quantified using a fluorometric ELISA and bioactivity confirmed with a neuronal culture bioassay. Immunohistochemical techniques and computerized image analysis were used to assess the rate and volume of axonal and Schwann cell regeneration. The delivery of NGF to the site of injury produced an increase in the rate ( P≤0.007) and volume ( P≤0.004) of both axonal and Schwann cell regeneration when compared to conduits of plain fibronectin. We conclude that the local delivery of NGF by impregnated fibronectin conduits enhances axonal regeneration.

Nerve Growth Factor Expression and Nerve Regeneration in Monkey Corneas After LASIK

2014 ◽  
Vol 30 (2) ◽  
pp. 134-139 ◽  
Author(s):  
Luxia Chen ◽  
Rui Hua Wei ◽  
Donald T. H. Tan ◽  
Roger W. Beuerman ◽  
Wenbo Li ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Nerve Regeneration ◽  
Nerve Growth ◽  
Nerve Growth Factor Expression ◽  
Factor Expression ◽  
Growth Factor Expression

scholarly journals Let-7 microRNAs Regenerate Peripheral Nerve Regeneration by Targeting Nerve Growth Factor

2015 ◽  
Vol 23 (3) ◽  
pp. 423-433 ◽  
Author(s):  
Shiying Li ◽  
Xinghui Wang ◽  
Yun Gu ◽  
Chu Chen ◽  
Yaxian Wang ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Peripheral Nerve Regeneration ◽  
Nerve Growth

Beneficial effect of nerve growth factor-7S on peripheral nerve regeneration through inside-out vein grafts: An experimental study

Microsurgery ◽  
2004 ◽  
Vol 24 (5) ◽  
pp. 408-415 ◽  
Author(s):  
Andreas I. Gravvanis ◽  
Dimosthenis A. Tsoutsos ◽  
George A. Tagaris ◽  
Apostolos E. Papalois ◽  
Charalampos G. Patralexis ◽  
...  
Keyword(s):  
Experimental Study ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Peripheral Nerve ◽  
Beneficial Effect ◽  
Nerve Regeneration ◽  
Peripheral Nerve Regeneration ◽  
Nerve Growth ◽  
Vein Grafts ◽  
Inside Out
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