Wide range of lineages of cells expressing nerve growth factor mRNA in the nerve lesions of patients with vasculitic neuropathy: An implication of endoneurial macrophage for nerve regeneration

Neuroscience ◽  
2004 ◽  
Vol 129 (1) ◽  
pp. 109-117 ◽  
Author(s):  
N. Mitsuma ◽  
M. Yamamoto ◽  
M. Iijima ◽  
N. Hattori ◽  
Y. Ito ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Nerve Regeneration ◽  
Vasculitic Neuropathy ◽  
Nerve Lesions ◽  
Nerve Growth ◽  
Wide Range

Nerve Growth Factor Enhances Nerve Regeneration through Fibronectin Grafts

1996 ◽  
Vol 21 (4) ◽  
pp. 514-522 ◽  
Author(s):  
I. H. WHITWORTH ◽  
R. A. BROWN ◽  
C. J. DORÉ ◽  
P. ANAND ◽  
C. J. GREEN ◽  
...  
Keyword(s):  
Image Analysis ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Schwann Cell ◽  
Nerve Regeneration ◽  
Axonal Regeneration ◽  
Cell Regeneration ◽  
Nerve Growth ◽  
Computerized Image Analysis ◽  
Immunohistochemical Techniques

Soluble fibronectin and nerve growth factor (NGF) promote axonal regeneration when placed in silicone tubes. We investigated the ability of orientated fibronectin mats to bind and release bioactive NGF and the possibility of augmenting axonal regeneration following axotomy by using fibronectin conduits impregnated with NGF. The release of NGF was quantified using a fluorometric ELISA and bioactivity confirmed with a neuronal culture bioassay. Immunohistochemical techniques and computerized image analysis were used to assess the rate and volume of axonal and Schwann cell regeneration. The delivery of NGF to the site of injury produced an increase in the rate ( P≤0.007) and volume ( P≤0.004) of both axonal and Schwann cell regeneration when compared to conduits of plain fibronectin. We conclude that the local delivery of NGF by impregnated fibronectin conduits enhances axonal regeneration.

The effects of gradients of nerve growth factor immobilized PCLA scaffolds on neurite outgrowth in vitro and peripheral nerve regeneration in rats

Biomaterials ◽  
2013 ◽  
Vol 34 (29) ◽  
pp. 7086-7096 ◽  
Author(s):  
Shuo Tang ◽  
Jixiang Zhu ◽  
Yangbin Xu ◽  
Andy Peng Xiang ◽  
Mei Hua Jiang ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Peripheral Nerve ◽  
Neurite Outgrowth ◽  
Nerve Regeneration ◽  
Peripheral Nerve Regeneration ◽  
Nerve Growth

Nerve Growth Factor Expression and Nerve Regeneration in Monkey Corneas After LASIK

2014 ◽  
Vol 30 (2) ◽  
pp. 134-139 ◽  
Author(s):  
Luxia Chen ◽  
Rui Hua Wei ◽  
Donald T. H. Tan ◽  
Roger W. Beuerman ◽  
Wenbo Li ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Nerve Regeneration ◽  
Nerve Growth ◽  
Nerve Growth Factor Expression ◽  
Factor Expression ◽  
Growth Factor Expression

Nerve growth factor-induced myoprotection in C2C12 muscle cells is mediated by α9β1 integrin via release of PGE2

2015 ◽  
Vol 26 (4) ◽  
Author(s):  
Keren Ettinger ◽  
Yoram Nevo ◽  
Cezary Marcinkiewicz ◽  
Philip Lazarovici
Keyword(s):  
Skeletal Muscle ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Cell Model ◽  
C2c12 Cells ◽  
Mitogen Activated Protein Kinase ◽  
Prostaglandin E ◽  
Potential Contribution ◽  
Nerve Growth ◽  
Wide Range

AbstractNerve growth factor (NGF) mediates a wide range of activities in the central nervous system including neuronal differentiation, synaptic plasticity, and neuroprotection. In addition, NGF places an important role in skeletal muscle physiology by some unknown mechanisms. We recently demonstrated that NGF conferred myoprotection toward ischemia in C2C12 skeletal muscle cell model, establishing an important trophic role for NGF in skeletal muscle.In this report, using ELISA and oxygen-glucose deprivation (OGD) assays, we investigated the potential contribution of prostaglandin ENGF-induced mitogen-activated protein kinase type 1 or 2 (ERK1/2) phosphorylation in C2C12 cells and in a dose-response fashion stimulated PGEThese results suggest that NGF activation of α9β1 integrin induced myoprotection by stimulation of ERK phosphorylation and release of cytoprotective PGE

Microsurgical repair of nerve lesions with nerve grafts: the effect of nerve growth factor 7S

2002 ◽  
Vol 25 (4) ◽  
pp. 187-192 ◽  
Author(s):  
Andreas Gravvanis ◽  
Efstathios Lykoudis ◽  
George Tagaris ◽  
Charalampos Patralexis ◽  
Apostolos Papalois ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Nerve Lesions ◽  
Nerve Growth ◽  
Nerve Grafts

scholarly journals Let-7 microRNAs Regenerate Peripheral Nerve Regeneration by Targeting Nerve Growth Factor

2015 ◽  
Vol 23 (3) ◽  
pp. 423-433 ◽  
Author(s):  
Shiying Li ◽  
Xinghui Wang ◽  
Yun Gu ◽  
Chu Chen ◽  
Yaxian Wang ◽  
...  
Keyword(s):  
Nerve Growth Factor ◽  
Growth Factor ◽  
Peripheral Nerve ◽  
Nerve Regeneration ◽  
Peripheral Nerve Regeneration ◽  
Nerve Growth

Beneficial effect of nerve growth factor-7S on peripheral nerve regeneration through inside-out vein grafts: An experimental study

Microsurgery ◽  
2004 ◽  
Vol 24 (5) ◽  
pp. 408-415 ◽  
Author(s):  
Andreas I. Gravvanis ◽  
Dimosthenis A. Tsoutsos ◽  
George A. Tagaris ◽  
Apostolos E. Papalois ◽  
Charalampos G. Patralexis ◽  
...  
Keyword(s):  
Experimental Study ◽  
Nerve Growth Factor ◽  
Growth Factor ◽  
Peripheral Nerve ◽  
Beneficial Effect ◽  
Nerve Regeneration ◽  
Peripheral Nerve Regeneration ◽  
Nerve Growth ◽  
Vein Grafts ◽  
Inside Out
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