Pivotal role of peroxisome proliferator–activated receptor γ (PPARγ) in regulation of erythroid progenitor cell proliferation and differentiation

2005 ◽  
Vol 33 (8) ◽  
pp. 857-864 ◽  
Author(s):  
E NAGASAWA ◽  
Y ABE ◽  
J NISHIMURA ◽  
T YANASE ◽  
H NAWATA ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Progenitor Cell ◽  
Peroxisome Proliferator ◽  
Erythroid Progenitor ◽  
Peroxisome Proliferator Activated Receptor ◽  
Erythroid Progenitor Cell ◽  
Cell Proliferation And Differentiation ◽  
Proliferation And Differentiation ◽  
Progenitor Cell Proliferation

scholarly journals Regulation of Cell Proliferation and Differentiation by PPARβ/δ

PPAR Research ◽  
2008 ◽  
Vol 2008 ◽  
pp. 1-5 ◽  
Author(s):  
Rolf Müller ◽  
Markus Rieck ◽  
Sabine Müller-Brüsselbach
Keyword(s):  
Cell Proliferation ◽  
Current Knowledge ◽  
Cell Cycle Control ◽  
Peroxisome Proliferator ◽  
Oncogenic Signaling ◽  
Peroxisome Proliferator Activated Receptor ◽  
Cell Proliferation And Differentiation ◽  
Proliferation And Differentiation ◽  
Oncogenic Signaling Pathways

Peroxisome proliferator-activated receptor-β/δ(PPARβ/δ) is a ligand-activated transcription factor with essential functions in the regulation of lipid catabolism, glucose homeostasis, and inflammation, which makes it a potentially relevant drug target for the treatment of major human diseases. In addition, there is strong evidence that PPARβ/δmodulates oncogenic signaling pathways and tumor growth. Consistent with these observations, numerous reports have clearly documented a role for PPARβ/δin cell cycle control, differentiation, and apoptosis. However, the precise role of PPARβ/δin tumorigenesis and cell proliferation remains controversial. This review summarizes our current knowledge and proposes a model corroborating the discrepant data in this area of research.

Novel role of 1,25(OH) 2 D 3 in induction of erythroid progenitor cell proliferation

2002 ◽  
Vol 30 (5) ◽  
pp. 403-409 ◽  
Author(s):  
Dora Ben Alon ◽  
Cidio Chaimovitz ◽  
Alexander Dvilansky ◽  
Gilles Lugassy ◽  
Amos Douvdevani ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Progenitor Cell ◽  
Erythroid Progenitor ◽  
Erythroid Progenitor Cell ◽  
Progenitor Cell Proliferation

p38α MAP kinase is essential in lung stem and progenitor cell proliferation and differentiation

2007 ◽  
Vol 39 (6) ◽  
pp. 750-758 ◽  
Author(s):  
Juan José Ventura ◽  
Stephan Tenbaum ◽  
Eusebio Perdiguero ◽  
Marion Huth ◽  
Carmen Guerra ◽  
...  
Keyword(s):  
Cell Proliferation ◽  
Map Kinase ◽  
Progenitor Cell ◽  
Cell Proliferation And Differentiation ◽  
Proliferation And Differentiation ◽  
Progenitor Cell Proliferation ◽  
P38α Map Kinase
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