scholarly journals Venous system in acute brain injury: Mechanisms of pathophysiological change and function

2015 ◽  
Vol 272 ◽  
pp. 4-10 ◽  
Author(s):  
Sheng Chen ◽  
Yujie Chen ◽  
Liang Xu ◽  
Nathanael Matei ◽  
Jiping Tang ◽  
...  
Keyword(s):  
Brain Injury ◽  
Acute Brain Injury ◽  
Venous System ◽  
Injury Mechanisms ◽  
And Function

Hypothermia for acute brain injury—mechanisms and practical aspects

2012 ◽  
Vol 8 (4) ◽  
pp. 214-222 ◽  
Author(s):  
H. Alex Choi ◽  
Neeraj Badjatia ◽  
Stephan A. Mayer
Keyword(s):  
Brain Injury ◽  
Acute Brain Injury ◽  
Injury Mechanisms

A methodology for detecting and exploring non-convulsive seizures in patients with acute brain injury

2014 ◽  
Vol 2 ◽  
pp. 396-399 ◽  
Author(s):  
DJ Albers ◽  
J Claassen ◽  
M Schmidt ◽  
G Hripcsak
Keyword(s):  
Brain Injury ◽  
Acute Brain Injury ◽  
Convulsive Seizures

Alterations of blood IL-8, TGF-beta1 and nitric oxide levels in relation to blood cells in patients with acute brain injury

Therapy ◽  
2006 ◽  
Vol 3 (3) ◽  
pp. 399-405
Author(s):  
Elham Hadidi ◽  
Mojtaba Mojtahedzadeh ◽  
Mohammad Hassan Paknejad ◽  
Shekoufeh Nikfar ◽  
Mohammad Jafar Zamani ◽  
...  
Keyword(s):  
Nitric Oxide ◽  
Brain Injury ◽  
Blood Cells ◽  
Acute Brain Injury

The ENIGMA Brain Injury Working Group: Approach, Challenges, and Potential Benefits

2019 ◽  
Author(s):  
Elisabeth A. Wilde ◽  
Emily L. Dennis ◽  
David F Tate
Keyword(s):  
Brain Injury ◽  
Working Group ◽  
Meta Analysis ◽  
Special Issue ◽  
Group Approach ◽  
Challenges And Opportunities ◽  
Brain Structure And Function ◽  
Potential Benefits ◽  
And Function ◽  
Neuroimaging Genetics

The Enhancing NeuroImaging Genetics through Meta-Analysis (ENIGMA) consortium brings together researchers from around the world to try to identify the genetic underpinnings of brain structure and function, along with robust, generalizable effects of neurological and psychiatric disorders. The recently-formed ENIGMA Brain Injury working group includes 8 subgroups, based largely on injury mechanism and patient population. This introduction to the special issue summarizes the history, organization, and objectives of ENIGMA Brain Injury, and includes a discussion of strategies, challenges, opportunities and goals common across 6 of the subgroups under the umbrella of ENIGMA Brain Injury. The following articles in this special issue, including 6 articles from different subgroups, will detail the challenges and opportunities specific to each subgroup.

Heart rate and blood pressure variability and baroreflex sensitivity in patients with acute brain injury

2005 ◽  
Vol 20 (4) ◽  
pp. 394 ◽  
Author(s):  
V. Papaioannou ◽  
M. Giannakou ◽  
N. Maglaveras ◽  
E. Sofianos ◽  
M. Giala
Keyword(s):  
Blood Pressure ◽  
Heart Rate ◽  
Brain Injury ◽  
Blood Pressure Variability ◽  
Baroreflex Sensitivity ◽  
Acute Brain Injury

scholarly journals Outcome Prognostication of Acute Brain Injury using the Neurological Pupil Index (ORANGE) study: protocol for a prospective, observational, multicentre, international cohort study

BMJ Open ◽  
2021 ◽  
Vol 11 (5) ◽  
pp. e046948
Author(s):  
Mauro Oddo ◽  
Fabio Taccone ◽  
Stefania Galimberti ◽  
Paola Rebora ◽  
Giuseppe Citerio
Keyword(s):  
Brain Injury ◽  
Latent Class ◽  
Acute Brain Injury ◽  
Institutional Review ◽  
Infrared Pupillometry ◽  
Poor Neurological Outcome ◽  
Registration Number ◽  
Poor Outcomes ◽  
Injured Patients ◽  
Neurological Pupil Index

IntroductionThe pupillary examination is an important part of the neurological assessment, especially in the setting of acutely brain-injured patients, and pupillary abnormalities are associated with poor outcomes. Currently, the pupillary examination is based on a visual, subjective and frequently inaccurate estimation. The use of automated infrared pupillometry to measure the pupillary light reflex can precisely quantify subtle changes in pupillary functions. The study aimed to evaluate the association between abnormal pupillary function, assessed by the Neurological Pupil Index (NPi), and long-term outcomes in patients with acute brain injury (ABI).Methods and analysisThe Outcome Prognostication of Acute Brain Injury using the Neurological Pupil Index study is a prospective, observational study including adult patients with ABI requiring admission at the intensive care unit. We aimed to recruit at least 420 patients including those suffering from traumatic brain injury or haemorrhagic strokes, over 12 months. The primary aim was to assess the relationship between NPi and 6-month mortality or poor neurological outcome, measured by the Extended Glasgow Outcome Score (GOS-E, poor outcome=GOS-E 1–4). Supervised and unsupervised methods and latent class mixed models will be used to identify patterns of NPi trajectories and Cox and logistic model to evaluate their association with outcome.Ethics and disseminationThe study has been approved by the institutional review board (Comitato Etico Brianza) on 16 July 2020. Approved protocol V.4.0 dated 10 March 2020. The results of this study will be published in peer-reviewed journals and presented at conferences.Trial registration numberNCT04490005.

Sign in / Sign up

Export Citation Format

Share Document