Why are multiple pregnancy rates and single embryo transfer rates so different globally, and what do we do about it?

2020 ◽  
Vol 114 (4) ◽  
pp. 680-689
Author(s):  
G. David Adamson ◽  
Robert J. Norman
Keyword(s):  
Embryo Transfer ◽  
Multiple Pregnancy ◽  
Single Embryo Transfer ◽  
Pregnancy Rates ◽  
Transfer Rates

scholarly journals Theoretical Model of the Relationship between Single Embryo Transfer Rate and Multiple Pregnancy Rate in Japan

2012 ◽  
Vol 2012 ◽  
pp. 1-7 ◽  
Author(s):  
Syuichi Ooki
Keyword(s):  
Pregnancy Rate ◽  
Embryo Transfer ◽  
Multiple Pregnancy ◽  
Early Period ◽  
Reproductive Technology ◽  
Single Embryo Transfer ◽  
Pregnancy Rates ◽  
Sigmoid Curve ◽  
The Relationship ◽  
Multiple Pregnancy Rate

The purpose of the present study was to examine the effect of single embryo transfer (SET) in assisted reproductive technology (ART) on the reduction of the multiple pregnancy rate. We also estimated the monozygotic (MZ) twinning rates according to the SET diffusion indirectly. A reverse sigmoid curve was assumed and examined using nationwide data of SET from 2007 to 2009 in Japan. The multiple pregnancy rate decreased almost linearly where the SET pregnancy rate was between about 40% and 80% of regression approximation. The linear approximation overestimated multiple pregnancy rates in an early period and underestimated multiple pregnancy rates in the final period. The multiple pregnancy rate seemed to be influenced by the improvement of the total pregnancy rate of ART in the early period and by the MZ twinning after SET in the final period. The estimated MZ twinning rate after SET was around 2%.

Cumulative pregnancy rates support elective single embryo transfer (SET)

2004 ◽  
Vol 82 ◽  
pp. S129-S130 ◽  
Author(s):  
A. Criniti ◽  
G. Chow ◽  
L. Craig ◽  
A. Khabani ◽  
A. Thyer
Keyword(s):  
Embryo Transfer ◽  
Single Embryo Transfer ◽  
Pregnancy Rates ◽  
Elective Single Embryo Transfer

Embryo Glue: The Use of Hyaluronan in Embryo Transfer Media

2021 ◽  
Author(s):  
Beth Atkinson ◽  
Emma Woodland
Keyword(s):  
Embryo Transfer ◽  
Large Scale ◽  
Multiple Pregnancy ◽  
Single Embryo Transfer ◽  
Transfer Policy ◽  
Vitro Fertilization ◽  
Meta Analyses ◽  
Detrimental Impact ◽  
Robust Evidence

AbstractEmbryoGlue is available to patients at many in vitro fertilization clinics, usually at an additional cost. The efficacy of hyaluronan-enriched transfer medium (HETM) is supported by moderate quality evidence that indicates a significant improvement in clinical outcomes such as live birth rates for patients, including poorer prognosis women (i.e., maternal age factor [>35 years] and recurrent implantation failure). An increased multiple pregnancy rate has been reported with the use of HETM; therefore, a single embryo transfer policy should be considered in conjunction with the use of EmbryoGlue. There is no evidence to suggest that HETM has any detrimental impact, and therefore the use of HETM in clinics may be justified for a specific demographic of patients. Further robust evidence, in the form of meta-analyses or large-scale randomized controlled trials, is needed to build a sufficient consensus regarding the benefit of hyaluronan supplementation in embryo transfer media.

scholarly journals Rapid policy change to single-embryo transfer while maintaining pregnancy rates per initiated cycle

2013 ◽  
Vol 26 (5) ◽  
pp. 506-511 ◽  
Author(s):  
M.P. Vélez ◽  
I.-J. Kadoch ◽  
S.J. Phillips ◽  
F. Bissonnette
Keyword(s):  
Embryo Transfer ◽  
Policy Change ◽  
Single Embryo Transfer ◽  
Pregnancy Rates
Sign in / Sign up

Export Citation Format

Share Document