In-situ modification of castor oil with divalent metal ions like Zn (II), Cu (II), Co (II) and Ba (II) and their comparative antioxidant study by in-vitro methods

2019 ◽  
Vol 284 ◽  
pp. 213-218 ◽  
Author(s):  
Md Ikbal Ahmed Talukdar ◽  
Md. Khursheed Akram ◽  
Taruna Singh ◽  
Manzoor A. Malik ◽  
Ovas A. Dar ◽  
...  
Keyword(s):  
Metal Ions ◽  
Castor Oil ◽  
Divalent Metal ◽  
Divalent Metal Ions ◽  
In Vitro Methods ◽  
In Situ Modification

In Situ Encapsulation of Hydrogen Peroxide in a Silica Matrix in the Presence of Divalent Metal Ions (Mg2+and Ca2+)

2017 ◽  
Vol 56 (9) ◽  
pp. 2607-2614
Author(s):  
Fulya Sudur Zalluhoglu ◽  
Ezgi Melis Dogan ◽  
Naigambi Patience Namusuubo ◽  
Nese Orbey ◽  
Edwin Jahngen
Keyword(s):  
Hydrogen Peroxide ◽  
Metal Ions ◽  
Divalent Metal ◽  
Silica Matrix ◽  
Divalent Metal Ions

Influence of monovalent metal ions on metal binding and catalytic activity of the 10–23 DNAzyme

2020 ◽  
Vol 402 (1) ◽  
pp. 99-111
Author(s):  
Hannah Rosenbach ◽  
Jan Borggräfe ◽  
Julian Victor ◽  
Christine Wuebben ◽  
Olav Schiemann ◽  
...  
Keyword(s):  
Metal Ions ◽  
Metal Binding ◽  
Divalent Cations ◽  
Reaction Rates ◽  
Divalent Metal ◽  
Divalent Metal Ions ◽  
Monovalent Metal ◽  
Biophysical Techniques ◽  
Target Rna

AbstractDeoxyribozymes (DNAzymes) are single-stranded DNA molecules that catalyze a broad range of chemical reactions. The 10–23 DNAzyme catalyzes the cleavage of RNA strands and can be designed to cleave essentially any target RNA, which makes it particularly interesting for therapeutic and biosensing applications. The activity of this DNAzyme in vitro is considerably higher than in cells, which was suggested to be a result of the low intracellular concentration of bioavailable divalent cations. While the interaction of the 10–23 DNAzyme with divalent metal ions was studied extensively, the influence of monovalent metal ions on its activity remains poorly understood. Here, we characterize the influence of monovalent and divalent cations on the 10–23 DNAzyme utilizing functional and biophysical techniques. Our results show that Na+ and K+ affect the binding of divalent metal ions to the DNAzyme:RNA complex and considerably modulate the reaction rates of RNA cleavage. We observe an opposite effect of high levels of Na+ and K+ concentrations on Mg2+- and Mn2+-induced reactions, revealing a different interplay of these metals in catalysis. Based on these findings, we propose a model for the interaction of metal ions with the DNAzyme:RNA complex.

Interaction of divalent metal ions with the NADP+-malic enzyme from maize leaves

1991 ◽  
Vol 81 (4) ◽  
pp. 462-466 ◽  
Author(s):  
Maria Fabiana Drincovich ◽  
Alberto A. Iglesias ◽  
Carlos S. Andreo
Keyword(s):  
Metal Ions ◽  
Malic Enzyme ◽  
Divalent Metal ◽  
Divalent Metal Ions ◽  
Maize Leaves

scholarly journals Regulation of divalent metal ions to the aggregation and membrane damage of human islet amyloid polypeptide oligomers

RSC Advances ◽  
2021 ◽  
Vol 11 (21) ◽  
pp. 12815-12825
Author(s):  
Yajie Wang ◽  
Feihong Meng ◽  
Tong Lu ◽  
Chunyun Wang ◽  
Fei Li
Keyword(s):  
Metal Ions ◽  
Metal Binding ◽  
Membrane Damage ◽  
Islet Amyloid Polypeptide ◽  
Divalent Metal ◽  
Human Islet ◽  
Divalent Metal Ions ◽  
Islet Amyloid ◽  
Induced Membrane ◽  
Human Islet Amyloid Polypeptide

Their is a counteraction between a decrease in the disruptive ability of metal-associated oligomer species and an increase in the quantity of oligomers promoted by the metal binding in the activity of hIAPP induced membrane damage.

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