Gene expression and functional characterization of serum amyloid P component 2 in rock bream, Oplegnathus fasciatus

2015 ◽  
Vol 47 (1) ◽  
pp. 521-527 ◽  
Author(s):  
Seong Don Hwang ◽  
Jin-Sol Bae ◽  
Dong Hee Jo ◽  
Kwang Il Kim ◽  
Mi Young Cho ◽  
...  
Keyword(s):  
Gene Expression ◽  
Functional Characterization ◽  
Serum Amyloid ◽  
Oplegnathus Fasciatus ◽  
Amyloid P Component ◽  
Serum Amyloid P ◽  
Serum Amyloid P Component ◽  
Rock Bream ◽  
Amyloid P

Proteomic characterization of novel serum amyloid P component variants from human plasma and urine

PROTEOMICS ◽  
2004 ◽  
Vol 4 (6) ◽  
pp. 1825-1829 ◽  
Author(s):  
Urban A. Kiernan ◽  
Dobrin Nedelkov ◽  
Kemmons A. Tubbs ◽  
Eric E. Niederkofler ◽  
Randball W. Nelson
Keyword(s):  
Human Plasma ◽  
Serum Amyloid ◽  
Amyloid P Component ◽  
Serum Amyloid P ◽  
Serum Amyloid P Component ◽  
Human Plasma And Urine ◽  
Amyloid P

scholarly journals The Impact of Serum Amyloid P-Component on Gene Expression in RAW264.7 Mouse Macrophages

2016 ◽  
Vol 2016 ◽  
pp. 1-9 ◽  
Author(s):  
Dan Xi ◽  
Jinzhen Zhao ◽  
Jichen Liu ◽  
Haowei Xiong ◽  
Wenshuai He ◽  
...  
Keyword(s):  
Gene Expression ◽  
Differentially Expressed Genes ◽  
Serum Amyloid ◽  
Differentially Expressed ◽  
Dependent Manner ◽  
Amyloid P Component ◽  
Serum Amyloid P ◽  
Serum Amyloid P Component ◽  
The Impact ◽  
Amyloid P

Serum amyloid P-component (SAP) contributes to host defense and prevents fibrosis. Macrophages are the most abundant inflammatory cell type in atherosclerotic plaques. In the present study, using3H-cholesterol-labeled counting radioactivity assay, we demonstrated that the apoAI-mediated cholesterol efflux in RAW264.7 macrophages was increased by SAP treatment in a time- and dose-dependent manner. We analyzed global gene expression changes upon SAP treatment using RNA sequencing. As a result, a total of 175 differentially expressed genes were identified, of which 134 genes were downregulated and 41 genes were upregulated in SAP treated cells compared to control cells. Quantitative RT-PCR analysis confirmed decreased expression of 5 genes and an increase in expression of 1 gene upon SAP treatment. Gene ontology analysis showed that genes involved in response to stimulus were significantly enriched in differentially expressed genes. Beyond protein-coding genes, we also identified 8 differentially expressed long noncoding RNAs. Our study may provide new insights into mechanisms underlying the functional role of SAP in macrophages.

scholarly journals Isolation and characterization of C-reactive protein and serum amyloid P component from bovine serum.

1989 ◽  
Vol 51 (4) ◽  
pp. 723-732 ◽  
Author(s):  
Masami MORIMATSU ◽  
Hirofumi SAKAI ◽  
Kumiko YOSHIMATSU ◽  
Osamu MINOWA ◽  
Shizuo YAMAMOTO ◽  
...  
Keyword(s):  
Bovine Serum ◽  
Serum Amyloid ◽  
C Reactive Protein ◽  
Amyloid P Component ◽  
Reactive Protein ◽  
Serum Amyloid P ◽  
Isolation And Characterization ◽  
Serum Amyloid P Component ◽  
Amyloid P

scholarly journals Characterization of Serum Amyloid P Component From Human Aortic Atherosclerotic Lesions

1995 ◽  
Vol 15 (2) ◽  
pp. 252-257 ◽  
Author(s):  
X. A. Li ◽  
K. Hatanaka ◽  
H. Ishibashi-Ueda ◽  
C. Yutani ◽  
A. Yamamoto
Keyword(s):  
Serum Amyloid ◽  
Amyloid P Component ◽  
Serum Amyloid P ◽  
Atherosclerotic Lesions ◽  
Serum Amyloid P Component ◽  
Amyloid P
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